“…Evidence suggests that an excessive amount of ROS initiates oxidative damage and many other fatal diseases such as CVS diseases, cancers, aging, diabetes, atherosclerosis, and depression ( Ansari et al., 2017 ; Maria Michel et al., 2012 ; Nigri et al., 2004 ; Schetter et al., 2010 ). Because of the elevated amount of oxygen consumption and insufficient antioxidant protection against ROS, nerve cells become more vulnerable to oxidative damage ( Halliwell, 2006 ; Reza et al., 2018a ; Sharmin et al., 2020 ). However, natural antioxidants from traditional medicinal plants, vegetables, and fruits have received significant attention due to their aptitude to scavenge free radicals as well as enhance the body's own antioxidant system to prevent various disorders ( Akter et al., 2020 ; Hossain et al., 2018 ; Mamun et al., 2020 ).…”