“…Biochemical study of the rate of turnover of transseptal ligament components is not reported, possibly because of the difficulty in isolation of this ligament from gingiva for analysis. Skougaard et al (1970a,b), Kameyama (1975), Beertsen (19791, and Minkoff and Engstrom (1979), in autoradiographic studies utilizing 3H-proline, suggest that the rate of collagenous protein turnover is slower in the transseptal than in the periodontal ligament, a situation often cited as a factor in the relapse of orthodontically rotated teeth (Erikson et al, 1945;Huckaba, 1952;Thompson, 1955Thompson, , 1959Thompson et al, 1958;Reitan, 1959Reitan, , 1960Reitan, , 1967Edwards, 1968;Brain, 1969;Boese, 1969;Parker, 1972). Conversely, studies of intracellular collagen profiles by , Svoboda and Deporter (19811, and Deporter et al (19841, using electron microscopic stereology, suggest that the rate of collagenous protein turnover in gingiva and periodontal ligament may be very high.…”