Preliminary Assessment of Postoperative Adhesion Formation After Laser-Assisted Mesh Fixation to the Peritoneal Surface

Abstract

Further development of this technology is warranted.

Histologic assessment of mesh fixation following laser-assisted tissue soldering in a lapine model

“…Complete resorption had occurred by 6 weeks postoperatively. Laser assisted solder fixation caused minimal adhesion formation when mesh was covered by solder [39].…”

“…This preliminary study demonstrates that laser-assisted tissue soldering is feasible and is capable of achieving intraperitoneal mesh fixation without the use of staples or permanent means of mesh fixation to tissue. Previous work from our laboratory demonstrates that temperature controlled laser collagen soldering results in satisfactory acute tensile strengths after mesh fixation and demonstrates that adhesion formation is reduced in scenarios that cover the mesh material with the collagen solder [38,39]. Tensile strength measurements were conducted immediately following mesh fixation using the techniques and parameters of the current study.…”

Comparative Evaluation of Adhesions to Intraperitoneally Placed Fixation Materials: A Laparoscopic Study in Rats

“…Laparoscopic ventral hernia repair (LVHR) has become a standard method for repair of abdominal wall hernias [1][2][3]. In general, the technique consists of a reduction in the hernia contents, transabdominal insertion of an appropriate size and type of mesh, opening of the mesh intraperitoneally, and its fixation over the hernia defect on the posterior surface of the anterior abdominal wall [4][5][6][7].…”

Preliminary Assessment of Photoactivated Antimicrobial Collagen on Bioburden in a Murine Pressure Ulcer Model

“…[15][16][17][18] Previous work with derivatized collagen solder formulations demonstrated that high concentration preparations could be cast into films for subsequent sectioning into strips for application to the weld site. [19][20][21][22][23] Collagen is biocompatible and bioabsorbable, and can be used as a carrier for biologically relevant molecules and chromophores.…”

“…It is hydrophilic and behaves as a postoperative adhesion preventative when placed intraabdominally. 20,22,23 The material can be used as a carrier for biologically relevant molecules and FIG. 7.…”