Pregnancy-Related Acute Kidney Injury: Experience of the Nephrology Unit at the University Hospital of Fez, Morocco

Abstract

Introduction. Acute kidney injury (PRAKI) continues to be common in developing countries. The aim of this paper is to study AKI characteristics in pregnancy and identify the factors related to the unfavorable evolution. Methods. This prospective study was conducted in the University Hospital Hassan II of Fez, Morocco, from February 01, 2011 to January 31, 2012. All patients presenting PRAKI were included. Results. 37 cases of PRAKI were listed. Their ages varied from 20 to 41 years old, with an average of 29.03 ± 6.3 years and an average parity of 1.83. High blood pressure was the most common symptom (55.6%). Thirty-nine percent were oliguric. PRAKI occurred during the 3rd trimester in 66.6% of the cases and 25% of the cases in the postpartum. Hemodialysis was necessary in 16.2% of cases. The main causes were preeclampsia, hemorrhagic shocks, and functional, respectively, in 66.6%, 25%, and 8.3% of the cases. The outcome was favorable, with a complete renal function recovery for 28 patients. Poor prognosis was related to two factors: age over 38 years and advanced stage of AKI according to RIFLE classification. Conclusion. Prevention of PRAKI requires an improvement of the sanitary infrastructures with the implementation of an obligatory prenatal consultation.

Pregnancy Related Acute Kidney Injury at a Tertiary Care Center in Nepal

“…10,11 There was one (6.6%) maternal mortality in our study compared to 2.7% in the Moroccan study and 20% in the study by Najar et al 10,11 …”

“…10 In our series, PRAKI was more frequent in the postpartum period (93.3%). This is probably a reflection of reduction in cases in early pregnancy due to legalization of abortion and improving antenatal care.…”

Acute Kidney Injury in Pregnancy—A Single Centre Retrospective Study

“…8 In our study, the average age was 29.03±6.3 years, ranging from 18 to 40 years. The mean serum creatinine was 34.8mg/L±25.4 with a maximum value of 105mg/L and a minimum value of 14mg/L.…”

“…Caring for women diagnosed with acute kidney injury is a real challenge for nephrologists and all the medical team. 8 AKI usually occurs in the third trimester of pregnancy. Puerperal sepsis and thrombotic microangiopathy are seen in the postpartum period.…”

Acute Kidney Injury Epidemiological Aspects in Gravido-Puerperal Period in Parakou

“…In United States, Solomon et al indicated that a diet rich in fruits and vegetables would be as effective as the intake of specific food supplements to fight the metabolic acidosis responsible for exposure to kidney disease [9]. About 5.26% of the patients had HBP.…”