Pregnancy Rate After Myomectomy and Associated Factors Among Reproductive Age Women Who Had Myomectomy at Saint Paul’s Hospital Millennium Medical College, Addis Ababa: Retrospective Cross-sectional Study.

Abstract

Introduction: Uterine myoma occurs in 20-50% of reproductive age women. Uterine myomas may be associated with 5-10% of cases of infertility, but it is the sole cause or factor in only 2-3% of all infertility cases. Myomectomy is surgery done to remove myoma regardless of the methods.Objective: to assess impact of myomectomy on pregnancy rate and associated factors among reproductive age women who had myomectomy at St. Paul’s Hospital Millennium Medical College, in Addis Ababa. Methodology: Hospital based retrospective cross-sectional study was conducted to determine pregnancy rate after myomectomy & its associated factors. Patients who had myomectomy in SPHMMC from September, 2012 to September, 2017 were enrolled. Information was retrieved from hospital records & phone interviews with the patients. The strength of statistical association was measured by adjusted odds ratios and 95% confidence intervals. Statistical significance was declared at p-value < 0.05. Result: Among 180 females participated in this study, 52.2% got pregnant after myomectomy. The result showed that females with age >35 years were 0.31 times less likely to get pregnant after surgery than those ages 20-25 years [AOR=0.31(95%CI: 0.29-0.54)]. People with no infertility before surgery were 1.19 times more likely to be pregnant after surgery than those with unexplained infertility before the surgery [AOR=1.19(95%CI: 1.06-1.57)]. People with two uterine incisions were 0.06 times less likely [AOR=0.06(95%CI: 0.043-0.51)] while those with three or more than three incisions were 0.02 times less likely [AOR=0.02(95%CI: 0.002-0.22)] to get pregnant compared with those with one incision on uterine wallConclusion: Age, number of incision and infertility before surgery were significantly associated with rate of pregnancy after myomectomy.

Laparoscopic versus laparotomic myomectomy in infertility management and its pregnancy outcome in Nigeria

“…It is similar to the mean age of 35.8 ± 3.4 / 35.2 ± 3.6 years and 35.88 ± 3.57 / 32.36 ± 4.06 years obtained from previous comparative studies of these two groups [6,12]. The mean age of the women in our study was interestingly below 35 years which is known to be favourable to achieving pregnancy in post myomectomy patients with infertility [2,17,18].…”

“…Uterine leiomyoma is common among black women of reproductive age in Africa and it is associated with infertility [1]. Uterine leiomyoma is a benign tumour of the smooth muscle and connective tissues of the uterus [2,3].…”

Labour outcome following laparoscopic myomectomy in infertility patients in Port Harcourt Nigeria

“…This was comparable to similar studies with 35 years or below as the mean age of women who achieved pregnancy after laparoscopic myomectomy [2,11,17,18]. This finding supports previous studies showing that age was significantly associated with pregnancy rate after myomectomy [19]. Younger women have a higher pregnancy rate than older women as seen in a Senegalese study [11,18].…”