Pregnancy complicating systemic lupus erythematosus: a series of 86 cases

Abstract

Planned pregnancy during stable stage, appropriate treatment in pregnancy and close monitoring can improve the security of pregnancy complicating SLE. In situations that the drug treatment is ineffective and the mother and infant are threatened, or the fetus is mature, the pregnancy should be terminated promptly, thereby reducing the complications, and increasing the success rate of pregnancy and perinatal survival rate.

Systemic Lupus Erythematosus and Outcomes in First and Subsequent Births Based on Data From a National Birth Registry

“…SLE patients were more often diagnosed with renal disease before pregnancy. Renal disease is a concern because it has been associated with pregnancy complications, such as hypertension, early-onset preeclampsia, renal flare, fetal loss, preterm births, and low BW (5,(25)(26)(27)(28)(29). However, the rates of renal disease diagnosed before pregnancy in the present study (5% in the first pregnancy and 2.7% in subsequent pregnancies) were lower than those in a previous report (11%) (7).…”

A comprehensive review of the clinical approach to pregnancy and systemic lupus erythematosus

“…Observational studies and every day clinical practice showed that planned pregnancies are associated with lower risk of flare during pregnancy, as compared to unintended pregnancies [44,45]. The EULAR recommendations for women's health and the management of family planning/pregnancy in SLE and/or APS women [46] have proposed a useful 'check-list' of factors to be considered for preconception counselling and risk stratification (synthesized and adapted in Table 1).…”

Pregnancy outcomes in patients with systemic autoimmunity

“…The rate of live and healthy newborns in SLE ranges from 66% to 85% [2]. Pregnancy outcome is strictly related to the disease activity at conception [3].…”