Pregnancy as a Fundamental Determinant of Child Health: a Review

Tette, Edem M. A.; Intiful, Freda Dzifa; Asare, Anita Ago; Enos, Juliana Yartey

doi:10.1007/s13668-022-00416-1

Cited by 8 publications

(9 citation statements)

References 71 publications

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“…and microbiota can modulate the immune response [ 195 ]. Many studies have shown that children exposed early in life to microbiota present in farming/rural environments develop fewer allergic conditions than children living in the inner-city [ 204 , 205 ]. During pregnancy, the maternal and fetal immune system communicate in a bidirectional manner ( Figure 5 ).…”

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

“…The development and maturation of the immune system starts early in fetal life and continues throughout infancy and early childhood. In contrast, as a reduction in microbial diversity, dysbiosis induces intestinal inflammation and quantitative and/or qualitative abnormalities of the microbiota that may be associated with systemic immune, allergic, metabolic, and infectious disorders [ 195 , 204 , 205 ] as shown in Figure 5 .…”

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

“…For example, cesarean-born infants typically have a gut microbiome, with lower levels of Escherichia coli , Bifidobacterium and Bacteroides species compared with those delivered vaginally [ 206 ], and increased levels of Staphylococcus and Streptococcus , comparable with the maternal skin microbiome [ 207 ]. The infant gut microbiota is significantly affected by factors such as perinatal exposure to maternal and child nutrition, antibiotic use and contact with older siblings while prebiotic intake as fibers and oligosaccharides can improve immunity and metabolism [ 200 , 204 , 205 , 206 , 207 , 208 , 209 , 210 ] and promote a long-term protective effect against food allergies in the offspring. For example, early inoculation with spore-forming Clostridium class IV and XIV species and other bacteria has been shown to lead to decreased levels of circulating IgE in adulthood while colonization of H. influenzae, S. pneumoniae , or M. catarrhalis within the first month of life increases the risk of asthma, leading to high counts of atopic markers, such as eosinophils and serum IgE [ 209 , 210 , 211 ].…”

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

“…Prebiotics are substrates, typically indigestible carbohydrates, in foods that selectively stimulate the growth and metabolic activity of beneficial intestinal microbes and are used by the microorganisms, providing health benefits to the host. Fiber and oligosaccharides can improve immunity and metabolism [ 200 , 204 , 205 , 206 , 207 , 208 , 209 , 210 ], and their intake in pregnant and lactating mice increases the effect of Lactobacillus and Clostridium leptum and promotes a long-term protective effect against food allergies (FA) in the offspring [ 204 , 205 , 206 , 207 , 208 , 209 , 210 ]. Therefore, it is important to enrich the diet with substances that promote the growth of lactic acid bacteria, which are important in maintaining human health.…”

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

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Allergic Inflammation: Effect of Propolis and Its Flavonoids

Oršolić

2022

Molecules

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The incidence of allergic diseases and their complications are increasing worldwide. Today, people increasingly use natural products, which has been termed a “return to nature”. Natural products with healing properties, especially those obtained from plants and bees, have been used in the prevention and treatment of numerous chronic diseases, including allergy and/or inflammation. Propolis is a multi-component resin rich in flavonoids, collected and transformed by honeybees from buds and plant wounds for the construction and adaptation of their nests. This article describes the current views regarding the possible mechanisms and multiple benefits of flavonoids in combating allergy and allergy-related complications. These benefits arise from flavonoid anti-allergic, anti-inflammatory, antioxidative, and wound healing activities and their effects on microbe-immune system interactions in developing host responses to different allergens. Finally, this article presents various aspects of allergy pathobiology and possible molecular approaches in their treatment. Possible mechanisms regarding the antiallergic action of propolis on the microbiota of the digestive and respiratory tracts and skin diseases as a method to selectively remove allergenic molecules by the process of bacterial biotransformation are also reported.

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Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

Section: Role Of Propolis and Its Components In Allergymentioning

confidence: 99%

See 2 more Smart Citations

Allergic Inflammation: Effect of Propolis and Its Flavonoids

Oršolić

2022

Molecules

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“…A well-established relationship exists between fetal malnutrition and obesity and overweight risk later in life [ 3 , 4 ]. For instance, young men exposed to famine during the first half of their mothers’ pregnancy, as during the Dutch famine of 1944–1945, were found to have a higher obesity risk [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of prenatal maternal dietary exclusion on childhood obesity and overweight risk

Horne,

Kabir,

Alam

2024

PLoS ONE

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Background Child birthweight is a measure of fetal nutrition that is primarily determined by prenatal maternal (PM) diet. Child birthweight and child obesity/overweight risk are well established to be linked. Nevertheless, no studies have investigated the impact of PM dietary exclusion on child obesity/overweight risk or body mass index z-score (BMIz). Objectives The study aimed to determine whether PM dietary exclusion affected the child’s BMIz, obesity/overweight risk, whether child birthweight serves as a mediator of this, and whether PM use of dietary supplements can protect against this. Methods Waves within the years 2004–2019 from the Longitudinal Study of Australian Children, a population-based cohort study, were analyzed. The participants were aged 0 to 15 years during these waves of the study. Analysis was conducted using logistic and linear models. A total of 5,107 participants were involved in the first wave of the study. Results The PM exclusion of fish was associated with a higher risk of being underweight at age 14 or 15 years and mild-to-moderate obesity at age 6 or 7 years. The PM exclusion of egg was associated with a higher risk of being overweight at age 14 or 15 years. The exclusion of dairy was associated with more mixed effects. Mediation effects did not reach statistical significance. Moderation effects involving PM dietary supplement use, when they did occur, were associated with higher child BMIz and usually a higher risk of obesity/overweight. Conclusions Fish and eggs are likely important parts of PM diets for preventing childhood obesity and overweight. Further studies will be needed to determine reasons for this and the apparent adverse effects of dietary supplements on overweight/obesity risk.

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