Preeclampsia Risk in Relation to Maternal Mood and Anxiety Disorders Diagnosed Before or During Early Pregnancy

Qiu, Chunfang; Williams, Michelle A.; Calderon‐Margalit, Ronit; Cripe, Swee May; Sorensen, Tanya K.

doi:10.1038/ajh.2008.366

Cited by 118 publications

(98 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…(14) The use of street drugs showed no significant association with mental disorders, however, the quantity of drug users can be considered high, when taking into consideration the fact that these women were pregnant. This aspect is relevant, since in addition to being related to a higher predisposition to the development of mental disorders, (2) the use of street drugs can also bring physical consequences both to the pregnant women (premature labor, placental abruption, neurological alterations, among others) and to their babies (cognitive and motor deficits).…”

Section: Discussionmentioning

confidence: 99%

Prevalência de transtornos mentais e fatores associados em gestantes

et al. 2015

View full text Add to dashboard Cite

Objective: To identify the prevalence of mental disorders and associated factors in pregnant women. Methods: Cross-sectional study with 394 pregnant women, randomly and proportionally selected. Data were collected during home visits, using a semi-structured questionnaire. Bivariate logistic regression was used for the analysis. Results: A total of 51 pregnant women (12.94%) were diagnosed with mental disorder and this number was significantly higher among those between 19 and 30 years of age, unmarried, white skin colored, who were in the second trimester of pregnancy, had a chronic disease associated and had been hospitalized during the current pregnancy. Nine of them were taking psychotropic drugs, and antidepressants were the most commonly used drug. Conclusion: The prevalence of self-reported mental disorders was 12.94% and the associated variables were: age, marital status, skin color, pregnancy trimester, hospitalization during pregnancy and chronic disease. ResumoObjetivo: Identificar a prevalência de transtornos mentais e fatores associados em gestantes. Métodos: Estudo transversal realizado com 394 gestantes, selecionadas de forma aleatória e proporcional. Os dados foram coletados nos domicílios, com aplicação de questionário semiestruturado. Para a análise foi utilizada a regressão logística bivariada. Resultados: Referiram diagnóstico de transtorno mental 51 gestantes (12,94%) e isto foi significativamente maior entre aquelas com idade entre 19 e 30 anos, sem companheiro, de cor branca, que estavam no segundo trimestre de gestação, tinha alguma doença crônica associada e foi internada na gestação atual. Nove delas faziam uso de psicofármacos, sendo os antidepressivos os mais utilizados. Conclusão: A prevalência de transtornos mentais auto-referido foi de 12,94% e as variáveis associadas foram: idade, situação conjugal, cor, trimestre de gestação, internação durante a gestação e doença crônica.

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalência de transtornos mentais e fatores associados em gestantes

et al. 2015

View full text Add to dashboard Cite

show abstract

“…1 Approximately 15%-30% of women experience mood and anxiety disorders during pregnancy. 2,3 Self-reported symptoms of antenatal mood disorders are associated with risk behaviors (e.g., smoking 4 and substance use during pregnancy 5 ), pregnancy complications (e.g., preeclampsia 6,7,8 and low birth weight 9 ), and long term adverse outcomes in the mother (e.g. poor postpartum mental health 5 ) and her offspring (e.g.…”

mentioning

confidence: 99%

Association of Serum Vitamin D with Symptoms of Depression and Anxiety in Early Pregnancy

Huang

Arnold

Qiu

et al. 2014

Journal of Women's Health

119

View full text Add to dashboard Cite

Objective: To evaluate associations between early pregnancy 25-hydroxyvitamin D (25[OH]D) concentrations and antepartum depression and anxiety symptoms and potential modifiers thereof. Materials and Methods: In a pregnancy cohort (N = 498), we examined cross-sectional associations of early pregnancy (mean = 15.4 weeks gestation) serum 25[OH]D concentrations and depression and anxiety symptoms. Symptoms were measured using Depression, Anxiety, and Stress Scales (DASS-21) and Patient Health Questionnaire Depression Module (PHQ-9) instruments. Regression models were fit and effect modification by prepregnancy body mass index and leisure-time physical activity (LTPA) were assessed using interaction terms and stratified analyses. ( < 28.9 ng/mL) had 1.11 higher PHQ-9 scores than those in the highest quartile ( ‡ 39.5 ng/mL, p < 0.05). However, associations were attenuated and statistically insignificant in fully adjusted models. Inverse associations of 25[OH]D with depression symptoms were significant among participants who reported no LTPA, but not among women who reported any LTPA (interaction p = 0.018). Conclusions: Our study provides modest evidence for inverse cross-sectional associations of early pregnancy maternal vitamin D concentrations with antepartum depression symptoms. We also observed that these associations may be modified by physical activity.

show abstract

“…Kharaghani és mtsai kutatásában a középsúlyos, illetve súlyos depresszióval diagnosztizált nők 2,5-szer nagyobb valószí-nűséggel lettek praeeclampsiásak várandósságuk során [30]. Továbbá, az anya kór történetében szereplő koráb-bi pszichiátriai zavarok -különös tekintettel a depressziós és szorongásos kór képekre -szintén megnövelhetik a praeeclampsia kialakulásának esélyét [31].…”

Section: A Pszichés Faktorok Vizsgálata Praeeclampsiábanunclassified

A praeeclampsia pszichoszociális vonatkozásai

2015

View full text Add to dashboard Cite

A praeeclampsia kialakulásához egyes esetekben pszichés faktorok is hozzájárulhatnak neuroendokrin és immunoló-giai mechanizmusok közvetítése révén, amelyek közül kiemelhető a hypothalamus-hypophysis-mellékvesekéreg tengely aktivitásának fokozódása és a proinfl ammatorikus citokinek szérumszintjének emelkedése. A praeeclampsia egyes pszichés zavarok előfordulását is megnöveli, a hosszan tartó hospitalizáció, a kontrollvesztés érzése, a koraszülés vagy a magzat egészségkárosodása következtében. Emellett a kórkép tartósan fennálló neurokognitív panaszokat okozhat, amelyek szintén negatívan befolyásolhatják az életminőséget. Tekintettel arra, hogy az anya rossz mentális állapota a terhesség kimenetelét és a magzat fejlődését egyaránt károsan befolyásolhatja, a praeeclampsiás nők számára a pszichológiai segítségnyújtás előnyös lehet. Orv. Hetil., 2015, 156(50), 2028-2034. Kulcsszavak: praeeclampsia, terhesség, depresszió, hypothalamus-hypophysis-mellékvesekéreg tengely, pszichoterápia Psychosocial aspects of preeclampsiaDistress conditions during pregnancy may contribute to the development of preeclampsia by altering functions of the neuroendocrine and immune systems, e.g. activation of the hypothalamic-pituitary-adrenal axis and increase in plasma proinfl ammatory cytokines. Preeclampsia may also precipitate mental health problems due to long-term hospitalization or unpredictable and uncontrollable events such as preterm labor and newborn complications. Besides, preeclampsia may induce persistent neurocognitive complaints with a negative impact on patients' quality of life. As growing evidence indicates that poor maternal mental health has an adverse effect on pregnancy outcome and fetal development, psychosocial interventions may be benefi cial for women with preeclampsia. Rövidítések 11β-HSD2 = 11-béta-hidroxiszteroid-dehidrogenáz-2 izoenzim; ACTH = adrenokortikotrop hormon; CRH = corticotropin releasing hormon; EMDR = eye movement desensitization and reprocessing; HPA = hypothalamus-hypophysis-mellékve-sekéreg tengely; PPD = postpartum depresszió; PTSD = poszttraumás stressz zavar; SNRI = (selective serotonin-norepinephrine reuptake inhibitor) szelektív szerotonin-noradrenalin visszavételgátló; SSRI = (selective serotonin reuptake inhibitor) szelektív szerotoninvisszavétel-gátló A praeeclampsia a terhességek 5-8%-ában fellépő súlyos szövődmény, amely hypertoniában, vizeletfehérje-ürítés-ben nyilvánul meg. Jellemzően a terhesség második vagy harmadik trimeszterében jelentkezik, és az anyai és magzati mortalitás és morbiditás egyik vezető oka világ szerte. A kórkép patogenezise nem teljesen tisztázott. A praeeclampsia kialakulásában a placentáció zavara fontos szerepet játszik a terhesség korai szakaszában [1]. A rossz vérellátású, ezáltal hypoxiás placenta olyan faktorokat

show abstract

Preeclampsia Risk in Relation to Maternal Mood and Anxiety Disorders Diagnosed Before or During Early Pregnancy

Cited by 118 publications

References 31 publications

Prevalência de transtornos mentais e fatores associados em gestantes

Prevalência de transtornos mentais e fatores associados em gestantes

Association of Serum Vitamin D with Symptoms of Depression and Anxiety in Early Pregnancy

A praeeclampsia pszichoszociális vonatkozásai

Contact Info

Product

Resources

About