Predisposing factors for primary acquired nasolacrimal duct obstruction

Bülbül

Invest. Ophthalmol. Vis. Sci.

et al. 2015

Section: Resultsmentioning

confidence: 85%

“…It is associated with chronic inflammation and fibrosis of the nasolacrimal duct. 3 It is possible that delayed tear clearance in PANDO patients may result in decreased neural discharge from the ocular surface, and decreased lacrimal gland stimulation and involution.…”

mentioning

confidence: 99%

Lacrimal Gland Volume Changes in Unilateral Primary Acquired Nasolacrimal Obstruction

Bülbül

Invest. Ophthalmol. Vis. Sci.

et al. 2015

“…Primary acquired nasolacrimal duct obstruction (PANDO) usually affects women older than 40 years and presents with epiphora. Although its etiology is unclear, many predisposing factors such as previous conjunctival infections, nasal diseases, sinusitis, topical timolol or chloramid exposure are thought to be predisposing factors ( 1 2 3 ). Some authors consider morphology of bony nasolacrimal duct (BNLD) as a causative factor ( 4 5 6 ); among these studies, a narrower BNLD transverse diameter (TD) in PANDO patients than the control group is reported ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Morphometric Evaluation of Bony Nasolacrimal Canal in a Caucasian Population with Primary Acquired Nasolacrimal Duct Obstruction: A Multidetector Computed Tomography Study

et al. 2016

ObjectiveThe bony nasolacrimal duct (BNLD) morphology as a contributory factor in primary acquired nasolacrimal duct obstruction (PANDO) is still controversial. The objectives of this study were to evaluate the morphometric differences of BNLDs in unilateral PANDO patients between PANDO and non-PANDO sides, as compared with the control group using multidetector computed tomography (CT).Materials and MethodsBilateral BNLDs in 39 unilateral PANDO patients and 36 control subjects were retrospectively reviewed. CT images with 0.5-mm thickness were obtained with a 64-slice scanner. The length, volume, coronal orientation type, sagittal orientation angle of BNLD, and relative lacrimal sac-BNLD angle were assessed. The entrance, minimum and distal end transverse diameters (TD) of BNLD was investigated.ResultsThe mean minimum and distal end BNLD TDs measurements were significantly narrower in PANDO patients, both in PANDO and non-PANDO sides, as compared with the control group (p < 0.001 and p = 0.040, respectively); however, there were no significant differences between PANDO and non-PANDO sides within PANDO patients. The length, entrance TD, volume, coronal orientation type, sagittal orientation angle of BNLD, and relative lacrimal sac-BNLD angle were not significantly different between PANDO patients and control subjects, as well as between PANDO and non-PANDO sides within PANDO patients.ConclusionThe narrow mean minimum and distal end BNLD TD in PANDO patients, in both PANDO and non-PANDO sides, may be associated with PANDO development. The lack of difference between PANDO and non-PANDO sides within PANDO patients and some overlap between PANDO patients and control subjects suggest that narrow BNLD is not the sole factor.

“…It has been reported that the patients’ history of infectious conjunctivitis was one of the predisposing factors for the primary acquired nasolacrimal duct obstruction. 19 Patients with postoperative drug residues may have relatively narrow nasolacrimal ducts. For them, DCR or silicone intubation may be more suitable than the PIO surgery.…”

Section: Discussionmentioning

confidence: 99%

Combined Lacrimal Passage Probing and Tobramycin/Dexamethasone Ophthalmic Ointment Infiltration

Hong

Sun

et al. 2015

Medicine