Predictors of Willingness of the General Public to Receive a Second COVID-19 Booster Dose or a New COVID-19 Vaccine: A Cross-Sectional Study in Greece

Galanis, Petros; Vraka, Irène; Katsiroumpa, Aglaia; Σίσκου, Όλγα; Konstantakopoulou, Olympia; Κατσούλας, Θεόδωρος; Mariolis‐Sapsakos, Theodoros; Kaitelidou, Daphne

doi:10.3390/vaccines10071061

Cited by 25 publications

(39 citation statements)

References 46 publications

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“…In addition, vaccination status was a significant predictor of fear of vaccination in the regression analysis. These results are consistent with previous studies, showing that fear of vaccination-related harm and side effects is the crucial reason to refuse vaccination [ 4 , 6 , 7 , 8 , 9 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ]. Alzubaidi et al [ 59 ] recommended reducing fears about the adverse effects of vaccination as a prevention or intervention strategy to increase COVID-19 vaccination uptake.…”

Section: Discussionsupporting

confidence: 93%

“…For example, on 9 June 2021 (when the data were collected in the current study), there were 24–25% of fully vaccinated people in Germany, Poland, and Slovenia, whereas 56% in Israel [ 12 ]. The main barrier to vaccination is distrust in the effectiveness of vaccination and fear of vaccination side effects, including infertility, harm, severe disability, or even death [ 4 , 6 , 7 , 8 , 9 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…The main barrier to research seems to be a lack of reliable tools to measure the fear of vaccination. Previous studies have assessed fear, worry, or concerns about vaccination using self-developed single questions, which were never examined regarding reliability or validity e.g., [ 7 , 8 , 9 , 15 , 16 , 17 , 19 ]. Hamilton and Hagger [ 20 ] developed the Vaccination Concerns in COVID-19 Scale (VaCCS), but instead of fear, this tool measures beliefs and concerns about COVID-19 vaccines on 35 items included in eight subscales (socio-political, health beliefs and outcomes, trait measures, intentions to receive the COVID-19 vaccine).…”

Section: Introductionmentioning

confidence: 99%

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Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, Israeli, Slovenian, and German Adults during the COVID-19 Pandemic

Ochnik

Rogowska

Benatov

et al. 2022

IJERPH

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Although concerns about harm and side effects are among the most important factors determining vaccine hesitancy, research on the fear of vaccination is sparse. The purpose of this study is a validation the Fear of Coronavirus Vaccination Scale (FoCVVS), adapted from the Fear of COVID-19 Scale. A representative sample of 1723 young adults aged 20–40 from Poland, Israel, Slovenia, and Germany participated during two time-points of the third COVID-19 pandemic wave. The online survey included demographic variables and several well-being dimensions, including gender, vaccination status, fear of coronavirus (FoCV-19S), physical health (GSRH), life satisfaction (SWLS), and perceived stress (PSS-10), anxiety (GAD-7), and depression (PHQ-9). Exploratory factor analysis (EFA) was performed at T1, and confirmatory analysis (CFA) at T2. The second-order two-factor structure demonstrated the best fit and very good discriminant and convergent validation. The general factor of the FoCVVS included two subscales assessing the emotional and physiological symptoms of fear of vaccination. Unvaccinated people showed higher levels of fear of vaccination than those vaccinated. A vaccination status, fear of vaccination T1, and fear of COVID-19 T1 were significant predictors of fear of vaccination T2. Vaccination-promoting programs should be focused on decreasing fear and enhancing the beneficial effects of vaccination.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, Israeli, Slovenian, and German Adults during the COVID-19 Pandemic

Ochnik

Rogowska

Benatov

et al. 2022

IJERPH

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“…The pooled acceptance of booster dose COVID-19 vaccination in the European region was 86% (95% CI: 81–90%, I 2 = 99%), ranging from 97% (95% CI: 95–99%) [ 37 ] to 62% (95% CI: 59–65%) [ 28 ] ( Figure 8 ).…”

Section: Resultsmentioning

confidence: 99%

“…It has been shown that the prevalence of the behavioral intention to receive a COVID-19 booster dose among the general population is variable in different countries with a range of 62–67% in the U.S., 67–71% in Poland, and 94% in China [ 25 , 26 , 27 ]. Multiple factors are associated with the acceptance of booster doses of COVID-19 vaccination, including high levels of fear of COVID-19 (low complacency) and trust in COVID-19 vaccination (high confidence), as well as low levels of fear of a booster dose or a new COVID-19 vaccine [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

et al. 2022

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The World Health Organization (WHO) recommended coronavirus disease 2019 (COVID-19) booster dose vaccination after completing the primary vaccination series for individuals ≥18 years and most-at-risk populations. This study aimed to estimate the pooled proportion of COVID-19 vaccine booster dose uptake and intention to get the booster dose among general populations and healthcare workers (HCWs). We searched PsycINFO, Scopus, EBSCO, MEDLINE Central/PubMed, ProQuest, SciELO, SAGE, Web of Science, Google Scholar, and ScienceDirect according to PRISMA guidelines. From a total of 1079 screened records, 50 studies were extracted. Meta-analysis was conducted using 48 high-quality studies according to the Newcastle-Ottawa Scale quality assessment tool. Using the 48 included studies, the pooled proportion of COVID-19 vaccine booster dose acceptance among 198,831 subjects was 81% (95% confidence interval (CI): 75–85%, I2 = 100%). The actual uptake of the booster dose in eight studies involving 12,995 subjects was 31% (95% CI: 19–46%, I2 = 100%), while the intention to have the booster dose of the vaccine was 79% (95% CI: 72–85%, I2 = 100%). The acceptance of the booster dose of COVID-19 vaccines among HCWs was 66% (95% CI: 58–74%), I2 = 99%). Meta-regression revealed that previous COVID-19 infection was associated with a lower intention to have the booster dose. Conversely, previous COVID-19 infection was associated with a significantly higher level of booster dose actual uptake. Subgroup analyses revealed that the pooled booster dose acceptance in the WHO region of the Americas, which did not include any actual vaccination, was 77% (95% CI: 66–85%, I2 = 100%). The pooled acceptance of the booster dose in the Western Pacific was 89% (95% CI: 84–92%, I2 = 100), followed by the European region: 86% (95% CI: 81–90%, I2 = 99%), the Eastern Mediterranean region: 59% (95% CI: 46–71%, I2 = 99%), and the Southeast Asian region: 52% (95% CI: 43–61%, I2 = 95). Having chronic disease and trust in the vaccine effectiveness were the significant predictors of booster dose COVID-19 vaccine acceptance. The global acceptance rate of COVID-19 booster vaccine is high, but the rates vary by region. To achieve herd immunity for the disease, a high level of vaccination acceptance is required. Intensive vaccination campaigns and programs are still needed around the world to raise public awareness regarding the importance of accepting COVID-19 vaccines needed for proper control of the pandemic.

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Willingness to receive COVID‐19 booster dose and its associated factors in Ghana: A cross‐sectional study

Storph

Essuman

Duku‐Takyi

et al. 2023

Health Science Reports

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Background and Aim The COVID‐19 booster dose has been cited as an important supplement for the control of the COVID‐19 pandemic due to reports of waning immunity among fully vaccinated persons. Determining factors that would affect its acceptability is necessary for initiating successful vaccination programs. In this study, we aimed to evaluate the factors associated with the acceptability of the COVID‐19 booster dose in Ghana. Methods We conducted an online cross‐sectional survey among the public. A self‐administered questionnaire was used to collect information on demographic characteristics, willingness to vaccinate, perceptions toward COVID‐19 vaccines, and trust in the government. Participants provided reasons and sources of advice that may affect their willingness to accept a booster dose. Using IBM SPSS and R Statistic; descriptive, univariate, and multivariate analyses were performed. Results Out of 812 respondents, 375 (46.2%) intended to accept the booster dose. Individuals who were males (adjusted odds ratio [aOR] 1.63, 95% confidence interval [CI] 1.07−2.48), had previously received other forms of vaccination twice (aOR 1.96, 95% CI 1.07−3.57) or in most years (aOR 2.51, 95% CI 1.38−4.57), tested positive for COVID‐19 (aOR 3.46, 95% CI 1.23−10.52), have high trust in government (aOR=1.77, 95% CI: 1.15‐2.74) and had positive perceptions regarding COVID‐19 vaccines (OR = 14.24, 95% CI: 9.28−22.44) were more likely to accept a booster dose. Experiencing side effects from the primer dose (aOR 0.12, 95% CI 0.08−0.18) was associated with reduced acceptance. Concerns about vaccine safety and efficacy were the common reasons impeding willingness, while advice from health professionals would be the most considered. Conclusion Low intention to accept the booster dose which is associated with a range of factors including the perception of vaccines and trust in the government, is a cause for concern. Thus, more effort would have to be taken through education and policy interventions to increase booster vaccine acceptability.

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Predictors of Willingness of the General Public to Receive a Second COVID-19 Booster Dose or a New COVID-19 Vaccine: A Cross-Sectional Study in Greece

Cited by 25 publications

References 46 publications

Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, Israeli, Slovenian, and German Adults during the COVID-19 Pandemic

Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, Israeli, Slovenian, and German Adults during the COVID-19 Pandemic

COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

Willingness to receive COVID‐19 booster dose and its associated factors in Ghana: A cross‐sectional study

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