Predictors of Pleural Adhesion Formation and Success of Pleurodesis in Patients With Pleural Effusion

Diagnostic and Prognostic Implications of Pleural Adhesions in Malignant Effusions

“…In one series of 26 patients with symptomatic MPE who underwent thoracentesis with drainage of 500 ml of PF per day for 3 consecutive days, pleural fibrin strands were detected by ultrasonography in 11 patients (42%) on day 6, suggesting an association between the number of thoracentesis and pleural adhesion formation. 12 However, Wolff et al 13 were unable to find such a relationship in 74 patients with MPE submitted to medical thoracoscopy. Half of these patients had some degree of pleural adhesions, duration of the effusion more than 5 months being the only significant predictor of the presence and extent of pleural adhesions.…”

“…The primary tumors are shown in Table 1. Analysis of histologic types indicated that the great majority of these malignancies were adenocarcinomas, (326) followed by mesotheliomas, (79) lymphomas,(47) epidermoid carcinomas,(33) small-cell carcinomas, ( 14) undifferentiated carcinomas (13), and sarcomas, (28) among others.…”

Predictors of septation in malignant pleural effusions: a retrospective cohort study

“…6 In two retrospective studies of patients with MPE who underwent thoracoscopy, adhesions (which may share some similarities in pathogenesis with pleural septations) 6,12 , were associated with lower pleural uid pH, higher pleural tumour burden 7 , and higher duration of effusion. 13 Apart from this, however, studies assessing clinical risk factors for development of pleural uid septations in MPE are lacking. Given that the incidence of MPE in the United States is estimated to be over 150 000 per year 3 , septated MPE represent a major cause of morbidity and a signi cant therapeutic challenge encountered by respirologists, oncologists, and thoracic surgeons.…”