2008
DOI: 10.1097/jto.0b013e318189f53d
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Diagnostic and Prognostic Implications of Pleural Adhesions in Malignant Effusions

Abstract: MPE are often loculated. The higher the grade of pleural adhesions, the greater the tumor burden exists, and paradoxically the lower the PF cytologic yield. The presence of pleural adhesions in MPE implies a poor prognosis.

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Cited by 45 publications
(40 citation statements)
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“…Intrapleural adhesions and septated effusions remain a common and burdensome clinical entity. The presence of adhesions carries a poor prognostic factor in patients with exudative pleural effusions and may render the pleural fluid drainage difficulty [2]. In dealing with this problem, intrapleural fibrinolytics may be a safe, easy, cost effective management option.…”
Section: Introductionmentioning
confidence: 97%
“…Intrapleural adhesions and septated effusions remain a common and burdensome clinical entity. The presence of adhesions carries a poor prognostic factor in patients with exudative pleural effusions and may render the pleural fluid drainage difficulty [2]. In dealing with this problem, intrapleural fibrinolytics may be a safe, easy, cost effective management option.…”
Section: Introductionmentioning
confidence: 97%
“…Series examining the diagnostic rate for malignancy of pleural cytology have reported a mean sensitivity of about 60% (range 40-87%) [25,32]. Sensitivity of pleural effusion cytology is reduced to 20% in case of severe pleural adhesion [33]. Definitive diagnosis based on cytology alone is not recommended because of the high risk of diagnostic error [14,18].…”
Section: Concepts Of Early Mpm and Mesothelioma In Situmentioning
confidence: 95%
“…Medical thoracoscopy has a diagnostic yield of 85-100% for malignancy [48,49]. In addition, assessment of the extent of pleural adhesions during thoracoscopy provides prognostic information in patients with MPEs, with patients with minimal or no adhesions having a medial survival of 9 months compared with the 5 months achieved in those with high levels of adhesions [50]. Complications include empyema and pleural bleeding, however, mortality is extremely low.…”
Section: Pleural Biopsymentioning
confidence: 98%