Predictors of Mortality in Patients Undergoing Mitral Valve Replacement

Abstract

Objective:Although mitral valve replacement is frequently performed in patients of all age groups, there are few studies available which determine the causes of operative mortality in mitral valve replacement especially in our region. Therefore, the objective of this study was to identify factors that are significantly associated with operative mortality in mitral valve replacement.Methods:From August 2012 to March 2013, 80 consecutive patients undergoing mitral valve replacement in a single tertiary hospital were included. Patients with a history of previous coronary artery bypass graft surgery or congenital heart problems were excluded from the sample. The included patients were observed for a period of 30 days. Pre and post-operative variables were used to identify significant predictors of mortality.Results:The overall hospital mortality (30 days) was 15%. High post-perative creatinine (P =0.05), high ASO titre (P=0.03), young age (P=0.011), low cardiac output (P=0.0001), small mitral valve size (P=0.002) and new onset of atrial fibrillation (P=0.007) were the significant independent predictors of operative morality.Conclusion:Mitral valve replacement can be performed in third world countries with limited resources with low mortality. However, optimal selection of mitral valve size can help to improve operative mortality.

Morbidity and Mortality in Patients Undergoing Mitral Valve Replacement at a Cardiovascular Surgery Referral Service: a Retrospective Analysis

“…Age, for example, has already been identified as an important predictor numerous times [ 4 , 7 , 8 , 12 - 14 , 18 - 21 ] , in agreement with what was found here. On the other hand, a number of other studies did not show its relationship with worse outcome [ 11 ] or even identified the inverse relationship [ 22 ] .…”

Predictors of Short-Term Mortality after Heart Valve Surgery: A Single-Center Study; Retrospective analysis

“…Previous studies have identi ed predictors of mortality in different patient populations undergoing valve surgery. In those undergoing mitral valve replacement, postoperative higher creatinine, low cardiac output, small mitral valve size, and new-onset atrial brillation were signi cant independent predictors of morality [9].…”

Common Predisposing Factors in Mortality of Patients After Undergoing Mitral Valve Surgery at a Tertiary Care Hospital in Karachi

“…Mitral valve dysfunction (MVD) due to rheumatic heart disease (RHD) is the most frequently encountered surgical disorder in the developing world [1,2]. With the help of medical treatment, patients experiencing symptoms attain improvement, but the therapy of choice is surgical intervention, either mitral valve repair or replacement (MVR/r) [3].…”

“…Patients with untreated degenerative MVD have substandard projection, with annual death rates reaching up to 34% [5]. While the untreated rheumatic MVD (rMVD) mortality rate and predictors of outcome after rMVD surgery are yet to be explored, one study from the same region has reported operative mortality of 15% in 80 patients undergoing MVR [2].…”