Predictors of Major Morbidity and Mortality After Pneumonectomy Utilizing The Society for Thoracic Surgeons General Thoracic Surgery Database

Shapiro, Mark; Swanson, Scott J.; Wright, Cameron D.; Chin, Cynthia; Sheng, Shubin; Wisnivesky, Juan P.; Weiser, Todd S.

doi:10.1016/j.athoracsur.2010.05.041

Cited by 181 publications

(130 citation statements)

References 29 publications

Supporting

Mentioning

106

Contrasting

Unclassified

Order By: Relevance

“…Left pneumonectomy is usually better tolerated than right pneumonectomy and some authors went on to say that ''the right pneumonectomy was a disease in itself'' (J. Deslauriers). The mortality associated with pneumonectomy remains significant (5-10%) and the right pneumonectomy carries a higher risk of death or complications than the left pneumonectomy, mainly attributable to bronchopleural fistula [33,37,43].…”

Section: Types Of Procedures and Approachesmentioning

confidence: 99%

“…In hospital death after lobectomy for lung cancer in the UK was reported as 2.6% in 2003 [32] and has now reduced to 2.3%. The 30-day mortality for pneumonectomy in the National Lung Cancer Audit (UK) was 5.8% and the in-hospital mortality for pneumonectomy was 5.6% over the period [2002][2003][2004][2005][2006][2007] in the Society of Thoracic Surgeons (STS) database [33].…”

Section: Assessment Of the Risk For Surgerymentioning

confidence: 99%

See 1 more Smart Citation

Surgery for nonsmall cell lung cancer

Lang-Lazdunski

2013

European Respiratory Review

View full text Add to dashboard Cite

Surgery remains the best curative option in patients with early stage lung cancer (stage I and II). Developments in minimally invasive techniques now allow surgeons to perform lung resections on elderly patients, patients with poor pulmonary function or significant cardiopulmonary comorbidities. New techniques, such as stereotactic radiotherapy and ablative procedures, are being evaluated in early-stage lung cancer and may represent an alternative to surgery in patients unfit for lung resection. Perioperative mortality rates have dropped significantly at most institutions in the past two decades and complications are managed more efficiently. Progress in imaging and staging techniques have helped cut futile thoracotomy rates and offer patients the most adequate treatment options. Large randomised trials have helped clarify the role of neoadjuvant, induction and adjuvant chemotherapy, as well as radiotherapy. Surgery remains an essential step in the multimodality therapy of selected patients with advanced-stage lung cancer (stage III and IV). Interventional and endoscopic techniques have reduced the role of surgery in the diagnosis and staging of nonsmall cell lung cancer, but surgery remains an important tool in the palliation of advanced-stage lung cancer. Large national/international surgical databases have been developed and predictive risk-models for surgical mortality/morbidity published by learned surgical societies. Nonetheless, lung cancer overall survival rates remain deceptively low and it is hoped that early detection/screening, better understanding of tumour biology and development of biomarkers, and development of efficient targeted therapies will help improve the prognosis of lung cancer patients in the next decade. @ERSpublications Despite progress in surgical techniques, radiotherapy techniques and targeted therapy, lung cancer prognosis remains poor

show abstract

Section: Types Of Procedures and Approachesmentioning

confidence: 99%

Section: Assessment Of the Risk For Surgerymentioning

confidence: 99%

Surgery for nonsmall cell lung cancer

Lang-Lazdunski

2013

European Respiratory Review

View full text Add to dashboard Cite

show abstract

“…Adverse outcome measure selection is based on clinical judgment, literature review and preliminary data analysis. The postoperative endpoints selected for lung surgery are: mortality (in-hospital mortality regardless of timing or within 30 days of the procedure), tracheostomy, reintubation, initial ventilator support greater than 48 hours, adult respiratory distress syndrome, bronchopleural fistula, pulmonary embolus, pneumonia, bleeding requiring reoperation, and myocardial infarction [49,50]. The selected major outcomes for esophageal surgery consist of the following conditions: bleeding requiring reoperation, anastomotic leak requiring medical or surgical treatment, reintubation, initial ventilation greater than 48 hours, pneumonia, or in-hospital mortality (same hospitalization) regardless of timing [51].…”

Section: Development Of a Clinical Risk Modelmentioning

confidence: 99%

Risk Prediction and Outcome Analysis

Haan¹

2012

Current Concepts in General Thoracic Surgery

View full text Add to dashboard Cite

“…Because of the dense scar tissue and inflammation surrounding major vascular, the fused pleural surface and the medical comorbidities, the morbidity of the patients with benign lung disease after pneumonectomy was almost three times higher than that for lung cancer patients. 5) So, some authors believed that this procedure is one of exaggerated risks and advised to be cautious when deciding whenever to perform it. [5][6][7] However, some surgeons advocate that pneumonectomy for benign disease can be performed with acceptable morbidity and mortality.…”

Section: Introductionmentioning

confidence: 99%

“…5) So, some authors believed that this procedure is one of exaggerated risks and advised to be cautious when deciding whenever to perform it. [5][6][7] However, some surgeons advocate that pneumonectomy for benign disease can be performed with acceptable morbidity and mortality. 3,4,8) We retrospectively evaluated the patients who underwent pneumonectomy, pleuropneumonectomy and completion pneumonectomy for treating benign disease to show the factors influencing the outcomes.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Pneumonectomy for Benign Disease: A Single Institution Retrospective Study on 59 Patients

Yang

Ding

Chang

et al. 2015

ATCS

View full text Add to dashboard Cite

Introduction: Pneumonectomy is the only curative treatment for some benign diseases but the operation is a challenging procedure. Herein, we present our experiences of pneumonectomy for 59 patients. Methods: The medical records of 59 patients who undergone pneumonectomy for benign lung diseases from 2008 to 2013 at the Division of Thoracic Surgery in Beijing Chest Hospital were retrospectively reviewed. Results: There were 23 male and 36 female patients. Three procedures including pneumonectomy, pleuropneumonectomy and completion pneumonectomy were used. The operative time and intraoperative blood loss were statistically different in the patients who undergone different operations. The operative time of the patients with and without tuberculosis had no difference but the intraoperative blood loss was more in the patients with tuberculosis (P = 0.035). The operative type, age and operative blood loss were relevant with the morbidity, the P value were 0.024, 0.042 and 0.027 respectively. Conclusions: Pneumonectomy for patients with benign disease may be more difficult than for patients with lung cancer, mean while pleuropneumonectomy and completion pneumonectomy may be greater challenges. But with careful patient selection and operative technique, it is a satisfactory treatment method for benign lung disease. The morbidity is acceptable and associated with operative type, age and operative blood loss.

show abstract

Predictors of Major Morbidity and Mortality After Pneumonectomy Utilizing The Society for Thoracic Surgeons General Thoracic Surgery Database

Cited by 181 publications

References 29 publications

Surgery for nonsmall cell lung cancer

Surgery for nonsmall cell lung cancer

Risk Prediction and Outcome Analysis

Analysis of Pneumonectomy for Benign Disease: A Single Institution Retrospective Study on 59 Patients

Contact Info

Product

Resources

About