Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms

Majid, Shahid; Salih, Mohammad; Wasaya, Rozina; Jafri, Wasim

doi:10.1186/1471-230x-8-52

Cited by 48 publications

(54 citation statements)

References 25 publications

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“…Allerdings wird bei Eisenmangelanämie nicht nur nach Karzinomen, sondern auch anderen Blutungsquellen gesucht, die ebenfalls behandelt werden sollen. In einer Studie war der FOBT ein unabhängiger Prädiktor einer GI Blutungsursache bei Patienten mit Eisenmangelanämie ohne GI Symptome [75]. In einer ähnlichen Studie wurden bei Patienten mit Eisenmangelanämie und positivem iFOBT GI Blutungsursachen (inklusive Karzinomen) häufiger gefunden [76].…”

Section: Diagnostischer Algorithmus Bei Eisenmangelanämieunclassified

Algorithmus zur Diagnose von Eisenmangelanämie

Jimenez

Lang

2016

Wien Med Wochenschr

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Section: Diagnostischer Algorithmus Bei Eisenmangelanämieunclassified

Algorithmus zur Diagnose von Eisenmangelanämie

Jimenez

Lang

2016

Wien Med Wochenschr

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“…Za Cameronove lezije se smatra da su jedan od uzroka hroničnog, ali nevidljivog -okultnog gubitka krvi ili, što je reĎe, vidljivog -manifestnog gastrointestinalnog krvarenja [9]. Neki autori su saopštili da u starijih bolesnika MCV < 60fl i pozitivan test na okultno krvarenje ukazuju na potencijalne krvareće lezije i u odsustvu gastrointestinalnih simptoma [10]. Druge studije su ustanovile da 36% bolesnika starijih od 65 godina, koji su anemični, imaju nedostatak gvožĎa [11].…”

Section: Wwwtmgorgrsunclassified

Iron deficiency anaemia: Single center study

Sretenovic¹,

Necin-Jovanovic²,

Stojanović³

et al. 2014

Tim Med Glas

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Sažetak:Uvod: Anemija je termin koji u kliničkoj praksi označava stanje koje karakterišu snižena koncentracija hemoglobina, smanjenje broja eritrocita i snižen hematokrit. Uzrok deficita gvožĎa, izolovanog ili u sklopu anemije, treba uvek ispitati jer može biti posledica ozbiljnih bolesti. Ispitivanjem je obuhvaćeno 110 odraslih bolesnika sa verifikovanom anemijom, a ciljevi ispitivanja su bili: 1.Utvrditi prosečnu starost ispitanika i raspodelu anemija po polu. 2. Utvrditi raspodelu vrednosti gvožĎa i feritina u serumu ispitanika sa anemijom, uz poseban osvrt na anemije sa deficitom gvožĎa. 3. Utvrditi sistem organa čije oboljevanje je najčešći uzrok nastanka anemije. 4. Odrediti distribuciju anemija prema morfološkoj klasifikaciji (MCV-u) u ispitivanom uzorku, i transfuzionu zavisnost na prezentaciji. Metod: Učinjena je prospektivna analiza 110 odraslih bolesnika sa anemijom u periodu od 15.10.2010. godine do 15.04.2011. godine, tj. tokom šest meseci. Isključujući faktor je bila trudnoća. Kod svih ispitanika uraĎeni su odreĎeni pregledi (endoskopija, gornja i donja, ultrazvučni pregled gornjeg abdomena, pregled urologa, kod oba pola i pregled ginekologa sa ginekološkim ultrazvukom, kod žena). UraĎene su laboratorijske analize: kompletne krvne slike, odreĎene vrednosti gvožĎa, feritina, TIBC, hepatogram, Coombsov test, direktni i indirektni, kao i analiza sedimenta urina i fekalnog okultnog krvarenja. Statistička obrada podataka učinjena je deskriptivnim i analitičkim metodama. Rezultati su prikazani tabelarno i grafički. Rezultati: Prosečna starost ispitanika bila je 59,71 godina, a dominirale su pripadnice ženskog pola. Anemija usled deficita gvožĎa potvrĎena je u 64,55% ispitanika, dok su snižene vrednosti feritina utvrĎene u 40,9% ispitanika. Najčešći uzrok anemije je bio lociran u sistemu organa za varenje verifikovan kao ulcus ventriculi, erosio ventriculi, erosio hitus haerniae, ulcus bulbi duodeni, nodduli haemoroidales sanqunans ili colitis ulcerosa. Transfuziono zavisnih bilo je 60%, od toga 41% sa hiposideremičnom anemijom. Zaključak: Neophodna je prevencija i rano prepoznavanje anemija uz adekvatno ispitivanje, čime se verifikuje osnovna bolest tj, uzrok anemije. Anemija usled deficita gvožĎa se leči supstitucijom preparatima gvožĎa u adekvatnoj dozi i dovoljno dugo, do normalizacije hemoglobina, nivoa gvožĎa u serumu i feritina dok transfuzije eritrocita treba maksimalno izbegavati. Ključne reči:anemija, deficit gvožĎa, dijagnoza, tretman, transfuzija. Summary:Introduction: Anaemia is a term used in clinical practice for decreased haemoglobin concentration, a decrease in number of erythrocytes and a low level of haematocrit. The cause of iron deficiency, isolated or in anaemia, should always be examined, since it can be a consequence of severe diseases. The examination included 110 adult patients with verified anaemia. The aims of this examination were: 1. To determine the average age of the examinees and anaemia distribution in males and females. 2. To determine the distribution of iron and ferrit...

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“…GIS bleeding result from primary GIS disease including benign or malignant neoplasm, ulceration, esophageal variceal, inflammatory bowel diseases, parasitic infections, arteriovenous malformations, bezoar, drugs such as nonsteroidal anti-inflammatory agents and steroids. Coagulopathy due to renal and hepatic diseases and inherited bleeding disorders are frequently associated with IDA [16][17][18][19]. IDA can be induced iatrogenically through excessive phlebotomies of blood donor, as a regular blood donation of 450 ml removes approximately 200 mg of iron from the body [20].…”

Section: Causesmentioning

confidence: 99%

“…In some cases, the serum total protein values are also low due to the concomitant loss of plasma. Abdominal imaging and endoscopy are recommended to visualize intestinal organs and to assess the gastrointestinal tract for evidence of ulceration, masses or vascular malformation [18,19].…”

Section: Tests For Blood Lossmentioning

confidence: 99%

Iron deficiency anemia: current strategies for the diagnosis and management

Kaya

2013

RHC

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Iron deficiency is one of the commonest nutritional deficiencies in the world. It is multifactorial and may be caused by lack of intake, blood loss and intestinal causes. Clinical features are highly variable, and most patients are asymptomatic. Typical laboratory features of iron deficiency anemia (IDA) include a hypochromic microcytic anemia, low serum iron level, high total iron binding capacity, low serum ferritin level. Usefulness of monitoring serum transferrin receptor level (sTfR) and hepcidin for identifying IDA have been examined in a few studies. Available data suggest that sTfR can potentially become a valuable tool for regular testing of patients in the future. Despite IDA is easily corrected with iron therapy, establishing the cause can be difficult, particularly in cases caused by disorders of iron transport. Education for clinician needs to focus on increasing awareness of the importance of failure respond to iron supplementation. The aim of this review was to outline the current strategies for the diagnosis and management of IDA in the light of the latest reports.

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Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms

Cited by 48 publications

References 25 publications

Algorithmus zur Diagnose von Eisenmangelanämie

Algorithmus zur Diagnose von Eisenmangelanämie

Iron deficiency anaemia: Single center study

Iron deficiency anemia: current strategies for the diagnosis and management

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