Predictors of complications associated with extracorporeal membrane oxygenation

Nakasato, Gislaine Rodrigues; Lopes, Juliana de Lima; Lopes, Camila Takáo

doi:10.1590/0034-7167-2018-0666

Cited by 4 publications

(3 citation statements)

References 32 publications

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“…In this study, the average ECMO duration and the ratio of long-term ECMO were higher in the life-threatening mechanical complication group than in the no mechanical complication group. Since long-term ECMO support can increase the chances of complications, 14,15 we normalized the rate of each complication and survival by the duration of ECMO (Table, Supplemental Digital Content 1, http://links.lww.com/ASAIO/ A589). It did not impact the incidence of hemorrhage and thrombotic complications; however, survival rates were significantly lower in the life-threatening mechanical complication group.…”

Section: Discussionmentioning

confidence: 99%

Catastrophic Mechanical Complications of Extracorporeal Membrane Oxygenation

et al. 2021

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Technical advances in extracorporeal membrane oxygenation (ECMO) have increased the number of cases that maintain longer duration. Long-term use of ECMO results in ECMO-related complications. Anticipation of the life-threatening mechanical complications and their management are critical for safe ECMO. In this study, we analyzed the incidence, nature, and risk factors of life-threatening mechanical complications during ECMO support. Furthermore, we presented our bedside algorithms to manage catastrophic ECMO complications. Data from 549 patients who underwent ECMO between December 2008 and December 2018 were retrospectively analyzed. The incidence of all lifethreatening mechanical complications was 4.0%. Accidental decannulation (1.3%) was most common, followed by abrupt falling circuit flows (1.1%), pump failure (1.1%), circuit rupture (0.4%), and air in circuit (0.2%). Most (90.9%) of life-threatening events required circuit and cannula change, while 9.1% required vein collapse relief procedure. There was no death related to the event; however, six (27.3%) died during ECMO due to the underlying disease for which ECMO was required, and three (13.6%) died after weaning from ECMO. Multivariate regression analysis showed that awake ECMO and long-term ECMO support were significantly associated with life-threatening mechanical complications (p < 0.01). Our algorithm safely managed catastrophic ECMO problems without event-related deaths.

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Section: Discussionmentioning

confidence: 99%

Catastrophic Mechanical Complications of Extracorporeal Membrane Oxygenation

et al. 2021

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“…Table 5 shows the recommended daily intake values 36 for the analytes Ca, Cu, Fe, K, Mg, Na, and Zn and the calculated values for conventional chicken, country chicken, turkey and Christmas chicken considering the recommended daily requirement of meat for an adult individual of 100 g per day. [36][37][38][39] The calculated values for all samples are below the recommended daily intake limit for the investigated metals, which shows that chicken's meat are a complementary part of a healthy diet and that there is a need for other sources providing the nutrients of these analytes, considered essential for the functioning of cellular metabolism. For Christmas chicken (spiced), Na presented a high intake value (403.60 mg per 100 g).…”

Section: Figures Of Merit For the Determination Of The Analytesmentioning

confidence: 99%

Development of an Analytical Method for the Determination of Metals in Chicken Breast by Microwave Induced Plasma Optical Emission Spectrometry (MIP-OES)

Pinto

Boeira

Lisboa

et al. 2019

J. Braz. Chem. Soc.

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An analytical method for the determination of Al, Ca, Cd, Cr, Cu, Fe, Hg, K, Mg, Na and Zn in breast of conventional, country and Christmas chicken and turkey samples using microwave induced plasma optical emission spectrometry (MIP-OES) technique was developed. Samples were decomposed in a digester block with a reflux system under conditions optimized using a central composite design as it follows: 2 g of sample, in 7.5 mL of HNO 3 during 180 min at 160 °C. The accuracy was evaluated by the analysis of standard reference material SRM 1546 meat homogenate (94 to 108%) and also by addition and recovery tests (80 to 121%). The highest concentrations, in mg kg -1 , of Al (2.77), Ca (88.3), Cu (1.99), Fe (3.65), K (3236), Mg (292.62) and Na (312.03) were found in the breast of conventional chicken sample. Zinc presented high value in the breast of turkey sample (10.6 mg kg -1 ). However, the found concentrations were lower than the daily consumption limit established by supervisory agencies and reference limits from Brazilian legislation. Cadmium, Cr and Hg presented values below limit of quantification. In this way, it is evident that chicken breast should be consumed in a complementary way in a healthy diet.

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“…Neurologic complications occur during or immediately after ECMO and are associated with poor survival [ 4 , 5 , 6 ]. Acute ischemic stroke, intracranial hemorrhage, seizures, cognitive decline, and brain death are a few of the short-term complications [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Cerebral Neural Changes in Venous–Arterial Extracorporeal Membrane Oxygenation Survivors

Yan

Fang

et al. 2023

Brain Sciences

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Background: Extracorporeal membrane oxygenation (ECMO) is used as temporary cardiorespiratory support in patients with critical ailments, but very little is known about the functional cerebral changes in ECMO survivors. Degree centrality (DC), a graph-based assessment of network organization, was performed to explore the neural connectivity changes in ECMO survivors compared to controls and their correlation with cognitive and neurological measures. Methods: This exploratory observational study was conducted from August 2020 to May 2022. ECMO survivors and controls underwent functional magnetic resonance imaging (fMRI) of the brain. We performed DC analysis to identify voxels that showed changes in whole-brain functional connectivity with other voxels. DC was measured by the fMRI graph method and comparisons between the two groups were performed. All participants underwent neuropsychological assessment (Montreal Cognitive Assessment, MoCA). Blood serum neuron-specific enolase and the Glasgow Coma Scale (GCS) were assessed in ECMO survivors. Results: DC values in the right insula and right precuneus gyrus were lower in ECMO survivors and higher in the right medial superior frontal gyrus compared to controls (all p < 0.001). Decreased connectivity in the right insular and right precuneus gyrus correlated with total MoCA scores, delayed recollection, and calculation (all p < 0.05). Increased serum NSE levels, GCS score, and GCS–motor response correlated with decreased connectivity in the right insular and right precuneus gyrus and increased connectivity in the right medial superior frontal gyrus (all p < 0.05). Conclusions: We showed that both functional impairment and adaptation were observed in survivors of ECMO, suggesting that neural connectivity changes may provide insights into the mechanisms that may potentially link ECMO survivors to neurological and cognitive disorders.

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Predictors of complications associated with extracorporeal membrane oxygenation

Cited by 4 publications

References 32 publications

Catastrophic Mechanical Complications of Extracorporeal Membrane Oxygenation

Catastrophic Mechanical Complications of Extracorporeal Membrane Oxygenation

Development of an Analytical Method for the Determination of Metals in Chicken Breast by Microwave Induced Plasma Optical Emission Spectrometry (MIP-OES)

Cerebral Neural Changes in Venous–Arterial Extracorporeal Membrane Oxygenation Survivors

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