Predictors of Atrial Fibrillation After Coronary Artery Bypass Grafting: A Bayesian Analysis

Perrier, Stéphanie; Meyer, Nicolás; Minh, Tam Hoang; Announe, Tarek; Bentz, Jonathan; Billaud, Philippe; Mommerot, Arnaud; Mazzucotelli, Jean‐Philippe; Kindo, Michel

doi:10.1016/j.athoracsur.2016.05.115

Cited by 68 publications

(61 citation statements)

References 40 publications

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“…Forest plot of weighted mean difference (WMD) for association between postoperative white blood cell count and recurrence of postoperative atrial fibrillation; CI -confidence interval; Pub -publication more clinical value than previously thought [4][5][6]. CBC test is one of the most common tests performed in patients hospitalised in cardiac care unit, ICU, and cardiac surgery wards, with multiple examinations before and after surgery [5][6][7][8]. It was recently reported that haematological parameters in CBC test, as well as coagulation and endothelial markers, may be reliable predictors of paroxysmal, persistent, and permanent AF in patients receiving pharmacotherapy, cardioversion, and catheter ablation [9].…”

Section: Discussionmentioning

confidence: 99%

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Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis

Weymann¹,

Ali-Hasan-Al-Saegh²,

Popov³

et al. 2018

Kardiol Pol

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Section: Discussionmentioning

confidence: 99%

“…Conventionally, diagnosis and management of AF have been focused on the patient's medical history, examination, and detection of AF through cardiac monitoring [6,7]. Complete blood count (CBC) is an imperative blood test in clinical practice routinely used in the examination of cardiovascular diseases [8,9].…”

Section: Introductionmentioning

confidence: 99%

Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis

Weymann¹,

Ali-Hasan-Al-Saegh²,

Popov³

et al. 2018

Kardiol Pol

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show abstract

“…Such events are known to impact healthcare costs, morbidity and mortality, postoperative discomfort, and tachycardia, necessitating rhythm reversal and prolonging ICU stays or forcing readmission. Hence, perioperative strategies to minimize occurrences of POAF are of great importance and are constantly under study [4, 5]. …”

Section: Introductionmentioning

confidence: 99%

Preoperative carbohydrate load and intraoperatively infused omega-3 polyunsaturated fatty acids positively impact nosocomial morbidity after coronary artery bypass grafting: a double-blind controlled randomized trial

Feguri

Lima

Borges

et al. 2017

Nutr J

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BackgroundA strategy of limited preoperative fasting, with carbohydrate (CHO) loading and intraoperative infusion of omega-3 polyunsaturated fatty acids (ω-3 PUFA), has seldom been tried in cardiovascular surgery. Brief fasting, followed by CHO intake 2 h before anesthesia, may improve recovery from CABG procedures and lower perioperative vasoactive drug requirements. Infusion of ω-3 PUFA may reduce occurrences of postoperative atrial fibrillation (POAF) and shorten hospital stays. The aim of this study was to assess morbidity (especially POAF) in ICU patients after coronary artery bypass grafting (CABG)/cardiopulmonary bypass (CPB) in combination, if preoperative fasts are curtailed in favor of CHO loading, and ω-3 PUFA are infused intraoperatively.MethodsFifty-seven patients undergoing CABG were randomly assigned to receive 12.5% maltodextrin (200 ml, 2 h before anesthesia), without infusing ω-3 PUFA (CHO, n = 14); water (200 ml, 2 h before anesthesia), without infusing ω-3 PUFA (controls, n = 14); 12.5% maltodextrin (200 ml, 2 h before anesthesia) plus intraoperative ω-3 PUFA (0.2 mcg/kg) (CHO + W3, n = 15); or water (200 ml, 2 h before anesthesia) plus intraoperative ω-3 PUFA (0.2 mcg/kg) (W3, n = 14). Perioperative clinical variables and mortality were analyzed, examining the incidence of POAF, as well as the need for inotropic vasoactive drugs during surgery and in ICU.ResultsTwo deaths occurred (3.5%), but there were no instances of bronchoaspiration and mediastinitis. Neither ICU stays nor total postoperative stays differed by group (P > 0.05). Patients given preoperative CHO loads (CHO and CHO + W3 groups) experienced fewer instances of hospital infection (RR = 0.29, 95%CI 0.09–0.94; P = 0.023) and were less reliant on vasoactive amines during surgery (RR = 0.60, 95% CI 0.38–0.94; P = 0.020). Similarly, the number of patients requiring vasoactive drugs while recovering in ICU differed significantly by group (P = 0.008), showing benefits in patients given CHO loads. The overall incidence of POAF was 29.8% (17/57), differing significantly by group (P = 0.009). Groups given ω-3 PUFA (W3 and CHO + W3 groups) experienced significantly fewer instances of POAF (RR = 4.83, 95% CI 1.56–15.02; P = 0.001).ConclusionPreoperative curtailment of fasting was safe in this cohort. When implemented in conjunction with CHO loading and infusion of ω-3 PUFA during surgery, expedited recovery from CABG with CPB was observed.Trial registrationNCT: 03017001

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“…The Framingham Heart Study demonstrated that greater pericardial fat deposition is associated with increased risk of AF incidence [16]. Severe obese defined as BMI of 35 kg/m 2 or higher was as a risk factor for postoperative AF following isolated coronary artery bypass grafting [17]. Nesfatin-1 regulates feeding behavior and appetite.…”

Section: Discussionmentioning

confidence: 99%

Association of serum nesfatin‐1 concentrations with atrial fibrillation

Duan

2018

The Kaohsiung J of Med Scie

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Nesfatin‐1, a newly discovered adipokine, inhibits inflammatory response. Inflammation is involved in the mechanism of atrial fibrillation (AF). We aim to determine the association between serum nesfatin‐1 concentrations and AF. A population of 200 patients with AF and 108 patients without AF were enrolled in this study. These patients were divided into three subgroups of paroxysmal AF, persistent AF, and permanent AF. Serum nesfatin‐1 concentrations were lower in AF patients than in controls. Logistic regression analysis showed that serum nesfatin‐1 concentrations were inversely associated with AF. Serum nesfatin‐1 concentrations in permanent AF patients decreased compared with those in persistent and paroxysmal AF groups. In addition, persistent AF patients showed reduced serum nesfatin‐1 concentrations compared with paroxysmal AF subjects. Serum nesfatin‐1 concentrations were negatively correlated with left atrial diameter. In conclusion, serum nesfatin‐1 concentrations were inversely correlated with AF development.

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Predictors of Atrial Fibrillation After Coronary Artery Bypass Grafting: A Bayesian Analysis

Cited by 68 publications

References 40 publications

Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis

Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis

Preoperative carbohydrate load and intraoperatively infused omega-3 polyunsaturated fatty acids positively impact nosocomial morbidity after coronary artery bypass grafting: a double-blind controlled randomized trial

Association of serum nesfatin‐1 concentrations with atrial fibrillation

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