Predictive Value of Cardiac Cachexia in Chronic Heart Failure

Дробышева, Елена Сергеевна; Tokmachev, Roman; Будневский, А. В.; Кравченко, А Я

doi:10.15829/1728-8800-2016-4-80-83

Cited by 2 publications

(2 citation statements)

References 25 publications

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“…There is an increasing number of studies indicating that the development of СHF (especially in patients with preserved ejection fraction) begins with a phase of systemic and cardiac inflammation, leading to an increase in the deposition of extracellular matrix and the accumulation of collagen in the interstitial and perivascular spaces [3,4]. This process is associated with increased left ventricular (LV) stiffness, diastolic and systolic dysfunction, and is also associated with a higher risk of hospitalization and cardiovascular death [5,6].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic and Prognostic Role of Cardiotrophin-1 in Patients with Heart Failure

Tokmachev¹,

Budnevsky²,

Podoprigora³

et al. 2021

PJMHS

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The review is devoted to the diagnostic and prognostic role of cardiotrophin-1 (CT-1) in patients with acute and chronic heart failure (CHF). The article provides information on the main regulatory effect of CT-1 in relation to the processes of cardiovascular remodeling. We considered the prospects of monitoring the plasma concentration of CT-1for the individualization of the assessment of cardiovascular risk in patients with CHF at various stages of the cardiovascular continuum. MeSH words: heart failure, cardiotrophin-1, hypertrophy, fibrosis, cytokines.

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Section: Introductionmentioning

confidence: 99%

Diagnostic and Prognostic Role of Cardiotrophin-1 in Patients with Heart Failure

Tokmachev¹,

Budnevsky²,

Podoprigora³

et al. 2021

PJMHS

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“…Atrial fibrosis triggers are the activation of the renin-angiotensinaldosterone system, inflammation, and oxidative stress. (5)(6)(7)(8) Furthermore, with an increase in the severity of symptoms of heart failure, the incidence and severity of AF increases.…”

Section: Introductionmentioning

confidence: 99%

Predictive Markers of Atrial Fibrillation Progression in Heart Failure

Tokmachev¹,

Kravchenko²,

Budnevsky³

et al. 2020

IJBM

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Atrial fibrillation (AF) is one of the most common arrhythmias encountered in clinical practice. It has been found that the presence of chronic heart failure increases the risk of AF by 5 times. Furthermore, with an increase in the severity of symptoms of heart failure, the incidence and severity of AF increases. To date, markers of AF progression are not clearly defined. In this regard, it is relevant and reasonable to identify such markers in patients with heart failure. The aim of this research was to study the prognostic value of the 6-minute walk test (6MWT), NT-proBNP level, and left ventricular diastolic dysfunction for AF progression in patients with chronic heart failure (CHF). The study involved 96 participants with stable Class II and III CHF (the NYHA Functional Classification), who were included in the regional registry of CHF patients in September-November 2014. The data obtained showed that in patients with CHF, an increase in the level of Nt-proBNP, impaired myocardial relaxation, and a decrease in 6MWT distance may serve as predictors of AF progression with the transition of arrhythmias to stable forms.

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Predictive Value of Cardiac Cachexia in Chronic Heart Failure

Cited by 2 publications

References 25 publications

Diagnostic and Prognostic Role of Cardiotrophin-1 in Patients with Heart Failure

Diagnostic and Prognostic Role of Cardiotrophin-1 in Patients with Heart Failure

Predictive Markers of Atrial Fibrillation Progression in Heart Failure

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