Predictive models of syncope causes in an outpatient clinic

Graf, Denis; Schlaepfer, J.; Gollut, Elisabeth; Melle, Guy van; Mischler, Corinne; Fromer, Martin; Kappenberger, Lukas; Pruvot, Étienne

doi:10.1016/j.ijcard.2006.12.007

Cited by 16 publications

(19 citation statements)

References 41 publications

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“…According to the literature, prodromal symptoms of nausea/vomiting are more common with neurogenic syncope [10, 12]; however, we did not observe such a difference in our patients. Similarly chest pain, sweating and palpitation, which point towards a cardiac aetiology, were found to be equally distributed in both neurogenic and cardiac aetiologies.…”

Section: Discussioncontrasting

confidence: 84%

“…Calkins et al [13] also observed that symptoms such as palpitation, nausea and diaphoresis are not significantly helpful in ascertaining the diagnosis of syncope. Similarly De Graf et al [10] concluded that specific symptoms cannot predict the cause of neurogenic syncope, rather it is the number of prodromal symptoms. Dizziness was prevalent in our patients, and more common in patients with neurogenic and syncope of unknown aetiology.…”

Section: Discussionmentioning

confidence: 99%

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Syncope: experience at a tertiary care hospital in Karachi, Pakistan

et al. 2008

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IntroductionOur aim was to determine the characteristics of patients presenting with syncope at a tertiary care hospital in Karachi, Pakistan.MethodsA review of medical records was conducted retrospectively at the Department of Medicine, Aga Khan University Hospital, Karachi. Patients aged 16 and above, admitted from January 2000 to December 2005 with the diagnosis of syncope made by the attending physician were included.ResultsA total of 269 patients were included (75% males, mean age: 57.4 years). Neurogenic (vasovagal) syncope was the most common cause (47%), followed by cardiogenic syncope (18%) and orthostatic syncope (9%). A total of 24% were discharged undiagnosed. Twenty patients (7.4%) did not have any prodrome. Common prodromal symptoms included dizziness (61%), sweating (25%), palpitations (19%), nausea/vomiting (19%) and visual symptoms (17%). The distribution of symptoms according to cause of syncope revealed only breathlessness to be significantly associated with cardiogenic syncope (p = 0.002). Most patients with cardiogenic syncope were aged above 40 (98%, p < 0.001), had coronary artery disease (72%, p < 0.001) and abnormal electrocardiogram at presentation (92%, p < 0.001).ConclusionDespite differences in burden of diseases, our findings were similar to those of published syncope literature. Further studies are needed to develop a protocol to expedite the evaluation and limit the work-up and admission in low-risk patients.

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Section: Discussioncontrasting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Syncope: experience at a tertiary care hospital in Karachi, Pakistan

et al. 2008

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“…On the other side, it is important to detect cardiac syncope because of its potentially fatal complications. When an underlying structural heart disease is suspected, work-up should include at least 12-lead EKG and echocardiography [3,4].…”

Section: Commentmentioning

confidence: 99%

Ictal bradycardia and asystole: An uncommon cause of syncope

Nový

Carruzzo

Pascale

et al. 2009

International Journal of Cardiology

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“…Syncopes remain unexplained in about 40% of the cases [1][2][3]. Very few predictive variables are associated with syncope recurrence [4].…”

Section: Introductionmentioning

confidence: 99%

“…Very few predictive variables are associated with syncope recurrence [4]. The yield of screening tests in neurally-mediated syncope (NMS) varies widely [2,[5][6][7][8]. In this context, a positive ATP-test identifies a subgroup of patients suffering from syncope or presyncope of unknown origin (SUO) likely to benefit from pacemaker therapy [9,10].…”

Section: Introductionmentioning

confidence: 99%