Prediction of Sudden Cardiac Arrest After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: ASA-SCARRE Risk Score

Veselka, Josef; Liebregts, Max; Cooper, Robert; Faber, Lothar; Januška, Jaroslav; Kashtanov, Maksim; Tesárková, Klára Hulíková; Hansen, Peter Riis; Seggewiß, Hubert; Shloydo, Eugene; Popov, Kirill; Hansvenclová, Eva; Poláková, Eva; Berg, Jurriën Ten; Stables, Rodney H; Jarkovský, Jiří; Bonaventura, Jiří

doi:10.1016/j.amjcard.2022.08.028

Cited by 9 publications

(2 citation statements)

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“…29 Secondly, the advances in the surgical septal myectomy technique (or alcohol ablation) and heart transplantation have further contributed to reducing the HCM-related mortality rate in younger patients. [30][31][32] Thirdly, young adults present less frequent HCM-related complications, such as heart failure and atrial fibrillation, as well as a lower competing risk of noncardiac death. 29…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the outcome for these patients has greatly improved following the use of ICDs for primary prevention of SCD, resulting in a greater proportion of younger patients surviving longer 29 . Secondly, the advances in the surgical septal myectomy technique (or alcohol ablation) and heart transplantation have further contributed to reducing the HCM-related mortality rate in younger patients 30–32 . Thirdly, young adults present less frequent HCM-related complications, such as heart failure and atrial fibrillation, as well as a lower competing risk of noncardiac death 29 …”

Section: Discussionmentioning

confidence: 99%

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Trends of hypertrophic cardiomyopathy-related mortality in United States young adults: a nationwide 20-year analysis

Zuin,

Porcari,

Rigatelli

et al. 2024

Journal of Cardiovascular Medicine

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Aims Data regarding hypertrophic cardiomyopathy (HCM)-related mortality in United States young adults, defined as those aged between 25 and 44 years, are lacking. We sought to assess the trends in HCM-related mortality among US young adults between 1999 and 2019 and determine differences by sex, race, ethnicity, urbanization and census region. Methods Mortality data were retrieved by the Centers for Disease Control and Prevention (CDC) Wide-Ranging Online Data for Epidemiologic Research (WONDER) dataset from January 1999 to December 2019. Age-adjusted mortality rates (AAMRs) were assessed using the Joinpoint regression modeling and expressed as estimated average annual percentage change (AAPC) with relative 95% confidence intervals (95% CIs). Results Over 20-year period, the AAMR from HCM in US young adults linearly decreased, with no differences between sexes [AAPC: −5.3% (95% CI −6.1 to −4.6), P < 0.001]. The AAMR decrease was more pronounced in Black patients [AAPC: −6.4% (95% CI −7.6 to −5.1), P < 0.001], Latinx/Hispanic patients [AAPC: −4.8% (95% CI −7.2 to −2.36), P < 0.001] and residents of urban areas [AAPC: −5.4% (95% CI −6.2 to −4.6), P < 0.001]. The higher percentages of HCM-related deaths occurred in the South of the country and at the patient's home. Conclusion HCM-related mortality in US young adults has decreased over the last two decades in the United States. Subgroup analyses by race, ethnicity, urbanization and census region showed ethnoracial and regional disparities that will require further investigation.

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