Prediction of Pre-Eclampsia by a Combination of Maternal History, Uterine Artery Doppler, and Mean Arterial Pressure (A Prospective Study of 200 Cases)

Prajapati, Saloni; Maitra, Nandita

doi:10.1007/s13224-012-0239-4

Cited by 17 publications

(17 citation statements)

References 13 publications

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“…[11][12][13][14][15] The factors that have been postulated to influence the risk of pre-eclampsia in various studies include Diabetes and Gestational Diabetes, 12-14-16-18 Obesity, 19 Multiple pregnancy. 17,18 Personal and family history of pre-eclampsia, 20 chronic infections, 21 UTI, 2 First pregnancy and Older maternal age or Younger than 20 years age, 2 Renal disease and autoimmune disorder, 16,17 prolonged interval between pregnancies [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] and History of abortion 8 and maternal diet. 22 Rationale: Knowledge and identification of sociodemographic and clinical risk factors for PE will help in estimating each woman's individualized risk and allow antenatal surveillance to be directed at these women and guide the healthcare providers for counseling of such women and possibly reduce the recurrence risk of PE if some modifiable risk factors (like obesity) are present.…”

Section: Introductionmentioning

confidence: 99%

Risk Factor Assessment for Preeclampsia: A Case Control Study

Verma¹,

Kapoor²,

Rajeev³

et al. 2017

IJMEDPH

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Background: Knowledge and identification of risk factors for preeclampsia will help in estimating each woman's individualized risk and possibly reduce the recurrence risk of preeclampsia. So this study was conducted to assess and compare the socio-demographic profile of women with and without preeclampsia and to determine the risk factors associated with preeclampsia. Methodology: This Hospital based Case control analytical study was conducted among 180 preeclampsia case and 180 control subjects at Mahila chikitsalaya, Jaipur, from June 2014 to May 2015. Results: Bivariate analysis found that preeclampsia was significantly associated with rural residence (p=0.033), joint family type (p=0.025), low education of head of family(p=0.007), young age at menarche (11-12years) (p<0.001) Anemia (P=0.034) and primiparity (p<0.001), Family history of preeclampsia (p<0.001) and hypertension (p=0.007) and Non veg. diet (p=0.042). Preeclampsia was not found to be significantly associated with history of previous abortion, inter pregnancy period and sex of last child of multiparous women and ANC characteristics, TT immunization, IFA tablets, twin pregnancy or gestational diabetes. In the multiple regression analysis, Age >30 years, Preobese (BMI=25-29.9), obese (BMI≥30 Kg/ m2), Primiparity, age of menarche at 12 years and rural residence were found to be independent risk factors associated with Preeclampsia. Conclusion: Age>30 years, Preobese, Obese, Primiparity, early age of menarche (12 years) and Rural residence were found as significant predictor for development of Preeclampsia. Most of these factors are non modifiable, but can be used to screen women during antenatal visits to identify those at higher risk of Preeclampsia.

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Section: Introductionmentioning

confidence: 99%

Risk Factor Assessment for Preeclampsia: A Case Control Study

Verma¹,

Kapoor²,

Rajeev³

et al. 2017

IJMEDPH

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“…In the mentioned study the mean of uterine arteries in pregnancy with adverse outcomes was 1.27 compared with 0.99 in normal pregnancies (p<0.001) [2]. Another study, by Saloni et al reported mean PI in normal pregnancies as 0.7 and 0.8 in women with adverse pregnancy outcome (preeclampsia, SGA, gestational hypertension) [9].…”

Section: Discussionmentioning

confidence: 80%

An Introduction to Determination of Mean Uterine Artery Doppler Pulsatility Index during Pregnancy for Predicting Adverse Pregnancy Outcome

Gitia¹,

Marsoosi²,

Moshfeghi³

2018

ME-JFM

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Objective: Preeclampsia and IUGR are known as the main causes of two adverse complications of pregnancies. Recently, uterine artery Doppler evaluation in first and second trimester has been used for screening of the above pregnancy-related complications. Study design: The goal of this study was to determine the most effective reference range value of mean PI in first, second and third trimesters in order to predict the adverse outcomes. This study was conducted in "Shariati" Hospital; Tehran medical University in the course of January 2014 and November 2017. Participants underwent ultrasound Doppler scans by a perinatalogist and were followed up until delivery. Mean PI (as compared between preeclampsia and IUGR groups) and the reference range value of PI (Pulsatility Index) for predicting adverse outcomes were determined. Three hundred and fifty pregnant women were included in this study. Result: Preeclampsia was detected in 132 (37.7%) and IUGR was seen in 134 (38.2%). Mean PI was significantly higher in preeclampsia and IUGR groups. Conclusion: The reference range for mean PI for predicting IUGR was found to be 1.82 with sensitivity and specificity of 53.4% and 87.5% (AUC=0.804 P<0.0001). The reference range for mean PI for predicting Preeclampsia was found to be 1.77 with sensitivity and specificity of 61.1% and 87.6% (AUC=0.761 P<0.0001). Application of uterine artery Doppler could be helpful in prediction of adverse pregnancy outcome.

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“…The combination of Doppler and the mother's positive history increased the rate of detection of early preeclampsia to 90.9% and 100%, with a false-positive rate of 5 and 10%, respectively. Prajapati et al 22 also asserted that Doppler of the uterine arteries in the second trimester of pregnancy is a useful method for identification of preeclampsia.…”

Section: Discussionmentioning

confidence: 99%

Doppler Sonography of Uterine Arteries in Pregnancy as a Marker of Preeclampsia

Medjedović¹,

Suljevic²,

Iglica³

et al. 2018

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Introduction: Preeclampsia is the cause of increased morbidity in mothers, and mortality and morbidity of both mothers and fetuses and newborns. The pathological process is already complete when the symptoms occur, and nothing concrete can be done to stop the process. Early identification of women at risk of developing preeclampsia is a key goal of antenatal care. Alongside chemical tests, Doppler sonography of the uterine arteries plays a major role in the prediction of preeclampsia. Aims: To establish the probability of resistance to blood flow in the uterine arteries and the existence of notching in the control and test groups. Materials and methods: The study comprised 60 subjects in the second trimester of pregnancy who were going for checkups during their pregnancy or had been hospitalized at the Maternity Clinic of Sarajevo UCC. All the subjects were divided into two groups, a control and a test group, in relation to the presence of pathological blood flow in the uterine arteries. As well as ultrasound results, the patients also provided an exhaustive history about their previous pregnancies, if any, and any relevant laboratory results. Results: A statistically significant difference was found in the average values of systolic and diastolic pressure during pregnancy between the control and the test group (p = 0.001). From an analysis of the resistance to blood flow in the uterine arteries in the control and test groups, we concluded that the flow on the side with the placenta and on the side without the placenta were physiological over five measurements in the control group of subjects. In the test group the largest number of cases of pathological flow were recorded, and there was also notching. Of the 21 subjects with a diagnosis of preeclampsia, there was notching in 10. Conclusion: Doppler sonography in the second trimester of pregnancy is a good prognostic marker for early discovery of preeclampsia.

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Prediction of Pre-Eclampsia by a Combination of Maternal History, Uterine Artery Doppler, and Mean Arterial Pressure (A Prospective Study of 200 Cases)

Cited by 17 publications

References 13 publications

Risk Factor Assessment for Preeclampsia: A Case Control Study

Risk Factor Assessment for Preeclampsia: A Case Control Study

An Introduction to Determination of Mean Uterine Artery Doppler Pulsatility Index during Pregnancy for Predicting Adverse Pregnancy Outcome

Doppler Sonography of Uterine Arteries in Pregnancy as a Marker of Preeclampsia

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