“…Capillary volume and skeletal muscle [Mb] likely remain constant from rest to exercise. However, capillary hematocrit has been observed to be less than that of the systemic circulation at rest (Kindig and Poole, 2001, Russell et al, 2003, Kindig and Poole, 1998, Barbee and Cokelet, 1971, Klitzman and Duling, 1979 and increases towards systemic hematocrit with increased flow, such as seen with muscle contractions Poole, 2001 andDesjardins andDuling, 1990). Thus, these factors may have a drastic affect on the relative contributions of Mb and Hb to NIRS.…”