Prediction of albuminuria by different blood pressure measurement methods in type 1 diabetes: a pilot study

Stergiou, George S.; Alamara, Christina; Drakatos, Antonis; Stefanidis, Constantinos J.; Vazeou, A.

doi:10.1038/hr.2009.82

Cited by 15 publications

(11 citation statements)

References 32 publications

(57 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In agreement with previous studies, we found that hypertensive individuals were at high risk for MAU, with blood pressure linearly associated with MAU [ 12 , 24 , 28 , 29 ]. A recent national hypertension survey in China found that blood pressure was controlled under 140/90 mmHg in 9.3% of hypertensive individuals [ 30 ].…”

Section: Discussionsupporting

confidence: 93%

Urinary albumin excretion and prevalence of microalbuminuria in a general Chinese population: a cross-sectional study

Yan

Guo

et al. 2014

BMC Nephrol

View full text Add to dashboard Cite

BackgroundMicroalbuminuria has been shown to be a risk factor for cardiovascular and renal disease in patients with hypertension and diabetes as well as in the general population. Urinary albumin excretion over 24 h is considered a ‘gold standard’ to detect microalbuminuria. Few studies have used 24-h urinary albumin excretion to analyze the prevalence of and related factors for microalbuminuira in a general Chinese population.MethodsThis study included 1980 adults aged 18–69 years from the Shandong-Ministry of Health Action on Salt and Hypertension (SMASH) Project 2011 survey. Blood pressure, height, weight and waist circumference were measured, and a venous blood and timed 24-h urine samples were collected from each participant. Linear and logistic regression analyses were used to test associations between established cardiovascular risk factors and microalbuminuria.ResultsThe median (25th–75th percentile) of 24-h urinary albumin excretion was 6.1 mg/d (4.5–8.7 mg/d) for all adults, 6.0 mg/d (4.4–8.5 mg/d) for men and 6.2 mg/d (4.6–8.9 mg/d) for women. The overall prevalence of microalbuminuria was 4.1% (95% confidence interval [CI]: 3.2–5.0%), 3.7% (95% CI: 2.9–4.5%) for men and 4.6% (95% CI: 3.7–5.5%) for women. Microalbuminuria was present in 8.1% (95% CI: 6.9–9.3%) of individuals with hypertension, 11.4% (95% CI: 10.0–12.8%) of those with diabetes and 15.6% (95% CI: 14.0–17.2%) of those with both. Multiple logistic regression analysis indicated that systolic blood pressure (odds ratio [OR] 1.02; 95% CI: 1.01–1.03) and fasting blood glucose (OR 1.19; 95% CI: 1.05–1.35) were the independent risk factors for microalbuminuria.ConclusionsAdults in the general population of Shandong Province have a moderate prevalence of microalbuminuria. Those with hypertension and diabetes are at high risk of having microalbuminuria, suggesting the need for screening and early intervention for microalbuminuria among these individuals.

show abstract

Section: Discussionsupporting

confidence: 93%

Urinary albumin excretion and prevalence of microalbuminuria in a general Chinese population: a cross-sectional study

Yan

Guo

et al. 2014

BMC Nephrol

View full text Add to dashboard Cite

show abstract

“…In diabetic hypertensive patients, concentric and eccentric left ventricular hypertrophy, increase in left ventricular muscle mass have been documented . In DM, the relationship between ABPM measurements and target organ damage has been showed in studies performed especially in adults . In this study, we planned to examine the relationship between elevated BP in diabetic children and early cardiac dysfunction.…”

Section: Discussionmentioning

confidence: 99%

“…Mobilograph (I.E.M., Stolberg, Germany) was programmed to measure BP at 20‐min intervals from 08:00 to 23:00 hours and at 30‐min intervals from 23:00 to 08:00 hours . ABPM data with less than 30 valid daytime BP measurements and/or less than 12 valid nighttime measurements were not included .…”

Section: Methodsmentioning

confidence: 99%

Can ambulatory blood pressure monitoring detect early diastolic dysfunction in children with type 1 diabetes mellitus: correlations with B-type natriuretic peptide and tissue Doppler findings

et al. 2014

View full text Add to dashboard Cite

show abstract

“…SBP has been demonstrated to independently determine cIMT in both children and adolescents . Changes in vascular function also occur at higher levels of childhood BP, including reduced brachial artery distensibility, higher PWV, and increased AIx, all of which indicate increasing arterial stiffness.…”

Section: Discussionmentioning

confidence: 99%

“…37 SBP has been demonstrated to independently determine cIMT in both children 38 and adolescents. 39 Changes in vascular function also occur at higher levels of childhood BP, including reduced brachial artery distensibility, 40,41 higher PWV, 42,43 and increased AIx, 44 all of which indicate increasing arterial stiffness. This is relevant to future cardiovascular disease, because increased vascular thickness 45 and stiffness 46 are associated with higher LVM in adolescents, a risk factor for future adult cardiovascular disease.…”

Section: Discussionmentioning

confidence: 99%

Is Daytime Systolic Load an Important Risk Factor for Target Organ Damage in Pediatric Hypertension?

Çonkar

Hacıkara

Bozabali

et al. 2015

J of Clinical Hypertension

View full text Add to dashboard Cite

The aim of this study was to compare ambulatory blood pressure (BP) monitoring (ABPM) data and determine which hypertension type is a risk factor in target organ damage. A total of 82 children (47 boys) with suspected hypertension based on office BP measurements and considered hypertensive by ABPM were studied. Target organ damage included the following: 35.3% hypertensive retinopathy, 25.6% microalbuminuria, 15.8% increased left ventricular mass index, 29.2% increased carotid intima-media thickness (cIMT), 24.3% high augmentation index (AIx), and 19.5% high pulse wave velocity (PWV). The association between BP load, PWV, and cIMT was statistically significant. There were significant correlations between daytime systolic BP load, PWV, AIx, and cIMT. A statistically significant difference was also detected between nighttime systolic BP load, PWV, and cIMT values and nighttime diastolic BP load levels and values of AIx and cIMT. There was also a statistically significant difference between the high level of nighttime diastolic BP load and cIMT. The authors found that target organ damage was seen more often in children with primary hypertension who had systolic loads.

show abstract

Prediction of albuminuria by different blood pressure measurement methods in type 1 diabetes: a pilot study

Cited by 15 publications

References 32 publications

Urinary albumin excretion and prevalence of microalbuminuria in a general Chinese population: a cross-sectional study

Urinary albumin excretion and prevalence of microalbuminuria in a general Chinese population: a cross-sectional study

Can ambulatory blood pressure monitoring detect early diastolic dysfunction in children with type 1 diabetes mellitus: correlations with B-type natriuretic peptide and tissue Doppler findings

Is Daytime Systolic Load an Important Risk Factor for Target Organ Damage in Pediatric Hypertension?

Contact Info

Product

Resources

About