Prediction of acute encephalopathy with biphasic seizures and late reduced diffusion in patients with febrile status epilepticus

Yokochi, Takaoki; Takeuchi, Takahito; Mukai, Jumpei; Akita, Yukihiro; Nagai, Kojiro; Obu, Keizo; Kakuma, Tatsuyuki; Matsuishi, Toyojiro

doi:10.1016/j.braindev.2015.07.007

Cited by 33 publications

(28 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the variables in which significant differences were observed in univariate analysis, AST, ALT, and LDH levels were strongly correlated with one another, in accordance with the findings of previous studies [6,7] (Suppl. Fig.…”

Section: Multivariate Analysis (Table 4)supporting

confidence: 91%

“…Although some previous studies have investigated risk factors associated with the morbidity or specific syndromic diagnosis of AE [5][6][7][8], to the best of our knowledge, no studies have aimed to identify acute-phase risk factors associated with mortality in children with SICF. In previous studies, we revealed that risk factors for morbidity could be obtained within 6 h of onset in patients with SICF [5,8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Early risk factors for mortality in children with seizure and/or impaired consciousness accompanied by fever without known etiology

Tomioka

Nagase

Tanaka

et al. 2018

Brain and Development

View full text Add to dashboard Cite

show abstract

Section: Multivariate Analysis (Table 4)supporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Early risk factors for mortality in children with seizure and/or impaired consciousness accompanied by fever without known etiology

Tomioka

Nagase

Tanaka

et al. 2018

Brain and Development

View full text Add to dashboard Cite

show abstract

“…AESD was established as a distinct type of acute encephalopathy in the 1990s 6) . An over whelming number of cases of AESD occur in Japan compared with other countries, and most reports are from Japan 7) . In Korea, a case of mild influenzaassociated AESD was reported in 2015 5) .…”

Section: Case Reportmentioning

confidence: 99%

Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion (AESD): Case Report and Review of the Literature

박선영¹,

홍재범²,

김세윤³

et al. 2016

journalofthekoreanchildneurologysociety

View full text Add to dashboard Cite

Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is a recently established subtype of encephalopathy syndrome. AESD is characterized by febrile status epilepticus on the first day, followed by transient recovery of conscious ness. A secondary cluster of complex seizures follows on day three to six, and reduced diffusion in the subcortical white matter can be observed by magnetic resonance imaging (MRI). Affected children have neurological sequelae of varying severity. The exact pathogenesis of AESD is unclear and clinicians often empirically manage patients with steroid pulse therapy and intravenous immunoglobulin. We herein report a case of a 13-month-old girl who was transferred to our hospital because of a secondary episode of afebrile seizures five days after a brief febrile convulsion. On day seven, diffusion-weighted MRI and the calculated apparent diffusion coefficient map indicated restricted diffusion in the subcortical white matter of both frontal lobes, the posterior cingulate gyrus, and the genu of the corpus callosum. Because the patient had no neurologic abnormalities after the second cluster of seizures, she underwent close observation with no medical treatment. She recovered completely without neurological sequelae and follow-up MRI on day 36 showed resolution of the restricted diffusion.

show abstract

“…Until now, AESD has been reported almost exclusively in the Japanese population. [ 3 – 6 ] In the literature, AESD has never been reported in the Chinese population. Herein, we report a rare case of AESD in China.…”

Section: Introductionmentioning

confidence: 99%

Acute encephalopathy with biphasic seizures and late reduced diffusion

Ma¹,

Xu²,

Chen³

et al. 2020

Medicine

View full text Add to dashboard Cite

Rationale: Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) has been reported almost exclusively in the Japanese population. Patient concerns: A 17-month-old male patient presented with fever and seizures, and subsequently fell into a coma. On the second day, he recovered consciousness. On the fourth day, he developed complex partial seizures and fell into a coma again. On day 10, the fever and seizures subsided. Head computed tomography on the first day showed no abnormalities. Brain diffusion-weighted images on the fourth day revealed reduced diffusion in the bilateral subcortical white matter. Diagnosis: A diagnosis of AESD was made. Interventions: The patient was treated with corticosteroids and intravenous immunoglobulin. Outcomes: At the 4-month follow-up, the patient was able to walk independently, and the epileptic seizures were well controlled. Lessons: AESD is a rare entity, and treatment with corticosteroids and intravenous immunoglobulin can lead to a favorable prognosis. Clinicians should be aware of this condition, and clinicoradiological features can suggest the diagnosis.

show abstract

Prediction of acute encephalopathy with biphasic seizures and late reduced diffusion in patients with febrile status epilepticus

Cited by 33 publications

References 23 publications

Early risk factors for mortality in children with seizure and/or impaired consciousness accompanied by fever without known etiology

Early risk factors for mortality in children with seizure and/or impaired consciousness accompanied by fever without known etiology

Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion (AESD): Case Report and Review of the Literature

Acute encephalopathy with biphasic seizures and late reduced diffusion

Contact Info

Product

Resources

About