We sought to determine the effects of classroom loudspeaker position, model of loudspeaker, and talker accent on mental effort or cognitive load, word clarity, sound quality, and word recognition. Thirty-one typically-developed university students whose native language is English rated and transcribed recorded sentences produced by a native English talker and a native Dutch talker speaking English. The listeners were seated in acoustically pre-calibrated locations in a classroom and were presented 10 sentences at conversational level in each of four randomized conditions: from a conventional classroom loudspeaker in front or mounted above them, and from a loudspeaker optimized for speech reproduction placed in front or mounted above them. At the front of the classroom was a muted video recording of one of the talkers delivering an online lecture. Results showed front-located speakers yielded less cognitive effort, better sound quality, and better word clarity—showing importance of congruence of loudspeaker/talker position.