Predicting risk of suicidal ideation in youth using a multigene panel for impulsive aggression

Koyama, Emiko; Zai, Clement C.; Bryushkova, Lyubov; Kennedy, James L.; Beitchman, Joseph H.

doi:10.1016/j.psychres.2019.112726

Cited by 18 publications

(12 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Impulsiveness in motivational-volitional model is not among the risk factors for suicidal ideation ( 5 ). This theoretical hypothesis was verified in model-based studies in which depression was included ( 13 , 14 ), which might be due to the strong mediating effect. Therefore, conclusion can be drawn that impulsiveness is an indirect risk factor for suicidal ideation.…”

Section: Discussionmentioning

confidence: 66%

“…In some studies, impulsiveness and depression are two independent variables related to suicidal ideation ( 10 – 12 ). Another study constructed a linear regression model ( 13 ), finding that depression independently predicted suicidal ideation and that impulsiveness affected suicidal ideation through interacting with traumatic experience. It is inconsistent about whether impulsiveness can independently lead to suicidal ideation and not clear whether impulsiveness can interact with depression in predicting suicidal ideation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model

Zhang

Zhang²,

Yang³

et al. 2022

Front. Psychiatry

View full text Add to dashboard Cite

ObjectiveThis study aims to investigate the indirect effect of impulsiveness on suicidal ideation through depression and the moderating effect of impulsiveness on the indirect effect in an integrated path model.MethodsSelf-rating depression scale (SDS), Barratt impulsiveness scale-11th version (BIS-11), and self-rating idea of suicide scale (SIOSS) were applied. A moderated mediation path model was established including impulsiveness, depression, and suicidal ideation as observed variables.ResultsThe main results revealed that the moderated mediation path model fit well in describing the relationships among impulsiveness, depression, and suicidal ideation. The indirect effect of impulsiveness mediated by depression and the moderating effect of impulsiveness on suicidal ideation was significant. Multiple comparisons showed that the indirect effects under different conditions of impulsiveness had statistical differences. The higher the impulsiveness was, the stronger the predictive effect of depression on suicidal ideation was.ConclusionsThe present study confirms that people who have impulsive traits are riskier to generate suicidal thoughts because they are more likely to suffer from depression and that people who are depressive have even higher risk to develop suicidal thoughts when they simultaneously have impulsive traits. In clinical and health care work, when considering depression to prevent suicidal ideation, impulsiveness needs to be monitored throughout the process of premorbid and onset stages of depression.

show abstract

Section: Discussionmentioning

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model

Zhang

Zhang²,

Yang³

et al. 2022

Front. Psychiatry

View full text Add to dashboard Cite

show abstract

“…In this article, we have considered self-harm more broadly by not distinguishing between suicidal and non-suicidal behaviours, or different methods of self-harm. Additionally, research has shown an association between self-harm/suicidal ideation and aggression (Hill et al, 2020;Koyama et al, 2020). It may be important to differentiate between NSSI, suicidal behaviours and ideation in order to identify their distinct and shared causal mechanisms in dual-harm.…”

Section: Limitationsmentioning

confidence: 99%

The Co-occurrence of Self-Harm and Aggression: A Cognitive-Emotional Model of Dual-Harm

et al. 2021

View full text Add to dashboard Cite

There is growing evidence that some individuals engage in both self-harm and aggression during the course of their lifetime. The co-occurrence of self-harm and aggression is termed dual-harm. Individuals who engage in dual-harm may represent a high-risk group with unique characteristics and pattern of harmful behaviours. Nevertheless, there is an absence of clinical guidelines for the treatment and prevention of dual-harm and a lack of agreed theoretical framework that accounts for why people may engage in this behaviour. The present work aimed to address this gap in the literature by providing a narrative review of previous research of self-harm, aggression and dual-harm, and through doing so, presenting an evidence-based theory of dual-harm – the cognitive-emotional model of dual-harm. This model draws from previous studies and theories, including the General Aggression Model, diathesis-stress models and emotional dysregulation theories. The cognitive-emotional model highlights the potential distal, proximal and feedback processes of dual-harm, the role of personality style and the possible emotional regulation and interpersonal functions of this behaviour. In line with our theory, various clinical and research implications for dual-harm are suggested, including hypotheses to be tested by future studies.

show abstract

“…One of the reasons for the low number of MAs among our patients with no chronic disease might be related to the patterns of suicidal behaviour seen in adolescents. Childhood traumatic experiences and impulsive behaviour are powerful determinants of suicidal ideation in teenagers (Koyama et al, 2020), therefore adolescents with no underlying disease may make a single attempt secondary to impulsive behaviour.…”

Section: Discussionmentioning

confidence: 99%

Youth suicide and hospital-presenting suicide attempts: Examination of risk factors for multiple suicide attempts in adolescence

Tubaş

Esen

Gündüz

et al. 2022

Int J Soc Psychiatry

View full text Add to dashboard Cite

Background: The suicide rate among adolescents around the world has increased rapidly. There are many risk factors for attempting suicide, but not all have been clarified yet. Therefore, it is very important to identify risk factors. This study evaluated adolescents with a history of suicide attempts and their association with chronic diseases. Besides, to check whether they attempted suicide multiple times. Other clinical features related to multiple suicide attempts were investigated. Method: This study used a multicentre, retrospective cross-sectional design; 253 adolescents admitted to emergency departments in 2019 for suicide attempts were evaluated. Results: Adolescents with chronic disease were at greater risk for both single and multiple suicide attempts and patients had a 6.14 times higher risk of multiple attempts ( p = .013). The likelihood of multiple attempts did not differ according to the presence of somatic or psychiatric disease. Multiple attempters were more likely to poison themselves with their therapeutic drugs ( p = .002). Conclusion: When adolescents with a chronic disease present to the emergency services after a single suicide attempt using their therapeutic drugs, families should be informed regarding the potential for further attempts.

show abstract

Predicting risk of suicidal ideation in youth using a multigene panel for impulsive aggression

Cited by 18 publications

References 33 publications

Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model

Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model

The Co-occurrence of Self-Harm and Aggression: A Cognitive-Emotional Model of Dual-Harm

Youth suicide and hospital-presenting suicide attempts: Examination of risk factors for multiple suicide attempts in adolescence

Contact Info

Product

Resources

About