Predicting risk for seroma development after axillary or inguinal sentinel lymph node biopsy in melanoma patients

Abstract

Male sex, inguinal localization, and smoking are risk factors for the development of seroma.

Risk factors for recurrence of malignant melanoma in patients with negative sentinel lymph node biopsy

“…Risk factors for recurrence of malignant melanoma in patients with negative sentinel lymph node biopsy Dear Editors, Sentinel lymph node biopsy (SLNB) is a standard procedure in the staging of cutaneous malignant melanoma, and guides decisions regarding adjuvant therapy [1,2]. Sentinel lymph node biopsy is generally associated with few complications [3,4] and was initially implemented to avoid the increased morbidity associated with radical dissection, which, in the current era of adjuvant programmed cell death protein 1 inhibitor (PD-1-inhibitor) and targeted therapies is performed mostly for macrometastasis [5]. The value of SLNB as a prognostic marker [6,7] may be reduced by the existence of false negative results, which have been reported in 2.0-18.4 % of patients [8][9][10][11][12].…”

“…Patients with a follow-up of less than six months were excluded. The SLNB procedure, indications for SLNB as well as histological examination of SLNs were described previously [2,3]. Comparisons between the clinicopathologic characteristics of the patient groups were performed using Student's t-test and chi-square analysis.…”

Az őrszemnyirokcsomó-áttét kimutatása 4 mm-nél vastagabb melanomában esélyt ad ígéretes adjuváns kezelésre

“…Vizsgálatukban a betegek 20,4%-ánál volt észlelhető valamilyen szövődmény. A leggyakoribb, SNB-hez társu-ló morbiditás esetükben a posztoperatív seromaképződés volt, az esetek 19,6%-ában fordult elő, és szignifikánsan gyakrabban fordult elő a lágyékhajlatban, valamint férfiak esetében [28].…”

The effect of smoking in melanoma outcome still remains an enigma

“…As the general role of smoking regarding melanoma prognosis is unclear, smoking is associated in general with many types of postoperative complications in various types of surgery. In a recently published paper by Ona‐Diana Persa et al . in a cohort of 615 patients, they identified smoking as an independent risk factor for seroma formation following sentinel node biopsy for the first time.…”