Predicting Glycemic Index and Glycemic Load from Macronutrients to Accelerate Development of Foods and Beverages with Lower Glucose Responses

Rytz, Andréas; Adeline, Dorothée; Lê, Kim-Anne; Tan, Denise; Lamothe, Lisa; Roger, Olivier; Macé, Katherine

doi:10.3390/nu11051172

Cited by 26 publications

(20 citation statements)

References 41 publications

(39 reference statements)

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“…As for the results of GI and GL, lower values have contributed to the reduced risk of cardiovascular disease and diabetes (15). They investigated lots of kinds of breakfast, and reported that the average GI was 68.0 ± 9.2, and GL was 14.7 ± 3.1 g/30g weight (15).…”

Section: Discussionmentioning

confidence: 99%

Response of Insulin Secretion to Small Amount of Meal on Low Carbohydrate Diet (LCD)

Hashimoto¹,

Ebe²,

Bando³

et al. 2020

Biomed Sci J

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Diabetic nutritional therapy has been changing from Calorie Restriction (CR) to a Low Carbohydrate diet (LCD). Authors et al. have developed LCD medically and socially through the Japan LCD promotion association (JLCDPA), and proposed meal tolerance test (MTT) using LCD breakfast. For our research protocol, healthy subjects (n=8, M/F=4/4, BMI 20.5kg/m 2 ) received 75g oral glucose tolerance test (OGTT) and MTT, and changes in blood glucose and immunoreactive insulin (IRI) were measured. LCD meal included energy 307kcal, protein 13.8g, fat 23.9g, and carbohydrate 5.7g. The results from 0-30 min in average showed: i) 75gOGTT; 87.3-124.6mg/dL, 4.9-41.4μU/mL, ii) LCD; 90.3-84.3mg/dL, 5.4-12.2μU/mL, respectively. Decreased glucose may be from enough ability to secrete insulin to a glucose stimulus. These results would become reference data for future diabetic research.

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Section: Discussionmentioning

confidence: 99%

Response of Insulin Secretion to Small Amount of Meal on Low Carbohydrate Diet (LCD)

Hashimoto¹,

Ebe²,

Bando³

et al. 2020

Biomed Sci J

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“…GI / GL was proposed by Jenkins et al, in which there are different carbohydrates for influencing potential metabolic responses with different glycemic responses (GR) [17]. The lower GI and GL have been beneficial for decreased risk of diabetes and cardiovascular disease (CVD) [18]. Among them, 42 breakfast cereals were investigated.…”

Section: Discussionmentioning

confidence: 99%

“…The factors included GI (in vivo versus predicted) and GL (g) for serving 30g (in vivo versus predicted). They showed that GI is 68 +/-9.2, GL (g) = 14.7 +/-3.1 g/30g, Sucrose = 20.1 +/-8.5g, Starch 51.1 +/-10.0 g [18].…”

Section: Discussionmentioning

confidence: 99%

Proposal of Meal Tolerance Test (MTT) For Investigating Ability of Insulin Secretion for Small Carbohydrate Load

Ebe

Hashimoto

Bando

et al. 2020

Diab Res Open Access

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Authors and collaborators have continued clinical practice and research on diabetes for long, and begun Low Carbohydrate Diet (LCD) at first in Japan. We have proposed super-, standard-, petite-LCD methods with 12%, 26%, 40% of carbohydrate, and developed medical and social LCD movement by Japanese LCD promotion association (JLCDPA). For research protocol, subjects were 10 healthy young medical staff. Two tests were 75gOGTT and meal tolerance test (MTT) of breakfast of super-LCD with 300kcal and 6g of carbohydrate. Blood glucose and immunoreactive insulin (IRI) were measured at 0 min and 30 min. Results of glucose and IRI in median value (0-30min) showed as follows: i) OGTT; 89.5 mg/dL to 130.5 mg/dL, 5.1 μU/mL to 40.6 μU/mL, ii) MTT; 93.5 mg/dL to 84.5 mg/dL, 4.9μU/mL to 10.6 μU/mL (significant increase, p<0.05). The increments of IRI for GTT (carbo-75g) and MTT (carbo-6g) were analyzed. There was a significant correlation between increments of IRI in GTT and MTT (p<0.05). Blood glucose in MTT tended to decrease from 0 min to 30 min. These results suggested that insulin secretion would be sufficient and relatively excessive for 6g of carbohydrate amount.

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“…The mechanism by which CGMs may be used to monitor diet is based on the fact that the evolution of blood glucose after a meal, also known as the postprandial glucose response (PPGR), depends on the macronutrients in the meal (e.g., carbohydrates, protein, fat, fiber). The major determinant of PPGRs is the amount of carbohydrates, but adding protein, fat, or fiber to a meal generally yields smaller spikes and lengthier responses [8,9]. This suggest that the shape of the PPGR can be used to recover the macronutrient composition of the meal.…”

Section: Introductionmentioning

confidence: 99%

A Sparse Coding Approach to Automatic Diet Monitoring with Continuous Glucose Monitors

Das

Sajjadi

Mortazavi

et al. 2021

ICASSP 2021 - 2021 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)

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Measuring dietary intake is a major challenge in the management of chronic diseases. Current methods rely on self-report measures, which are cumbersome to obtain and often unreliable. This article presents an approach to estimate dietary intake automatically by analyzing the post-prandial glucose response (PPGR) of a meal, as measured with continuous glucose monitors. In particular, we propose a sparse-coding technique that can be used to estimate the amounts of macronutrients (carbohydrates, protein, fat) in a meal from the meal's PPGR. We use Lasso regularization to represent the PPGR of a new meal as a sparse combination of PPGRs in a dictionary, then combine the sparse weights with the macronutrient amounts in the dictionary's meals to estimate the macronutrients in the new meal. We evaluate the approach on a dataset containing nine standardized meals and their corresponding PPGRs, consumed by fifteen participants. The proposed technique consistently outperforms two baseline systems based on ridge regression and nearest-neighbors, in terms of correlation and normalized root mean square error of the predictions.

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Predicting Glycemic Index and Glycemic Load from Macronutrients to Accelerate Development of Foods and Beverages with Lower Glucose Responses

Cited by 26 publications

References 41 publications

Response of Insulin Secretion to Small Amount of Meal on Low Carbohydrate Diet (LCD)

Response of Insulin Secretion to Small Amount of Meal on Low Carbohydrate Diet (LCD)

Proposal of Meal Tolerance Test (MTT) For Investigating Ability of Insulin Secretion for Small Carbohydrate Load

A Sparse Coding Approach to Automatic Diet Monitoring with Continuous Glucose Monitors

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