Predicted creatinine clearance to evaluate glomerular filtration rate in black Caribbean subjects

Abstract

The C-G formula for estimating GFR yields similar clinical values in black Caribbeans and in Caucasians, but the same limitations were observed in both ethnic groups.

Plasma Homocysteine Levels in Hyperthyroid Patients

“…The apparent close relation between the plasma homocysteine and thyroid hormone levels indicates a hormone effect on homocysteine metabolism, distribution, or clearence. A similar argument can be made for the creatinine and cholesterol responses [8][9][10][11][12][13][14].…”

“…Since measurement of creatinine clearance requires the collection of urine over a 24-hour period, which is inconvenient for patients and often leads to inaccurate collections we preferred the Cockcroft and Gault formula. This formula has been shown to have a significant correlation to GFR in the literature [2,9]. Plasma FT 3 , FT 4 and TSH were measured by chemiluminescent method.…”

Performance of the Cockcroft-Gault and MDRD equations in adult Nigerians with chronic kidney disease

“…This recommendation has been validated in several Caucasian and African-American patient populations [13][14][15][16][17][18][19][20][21][22]. Few reports exist among native Africans validating prediction equations in the prediction of the GFR [23][24][25].…”

Estimating Glomerular Filtration Rate

“…One data set was compiled from two publications (16,17), and another one was derived from three publications (18)(19)(20). One author provided two data sets, comprising published (21) and unpublished data. Because one study used a different protocol for mGFR (i.e., single-dose injection instead of continuous infusion of inulin), these data were not accepted for further analysis (15).…”

“…All SCr values were measured by the Jaffé method (alkaline picrate reaction) using Technicon (12,21), Express Plus (13,14), Hitachi 747 (16,17), and Hitachi 704 and 717 (18)(19)(20) autoanalyzers. No information on calibration of the creatinine assays between the laboratories was available.…”