Prediabetes diagnosis criteria, type 2 diabetes risk and dietary modulation: The CORDIOPREV study

Roncero-Ramos, Irene; Alcalá‐Díaz, Juan F.; Rangel‐Zúñiga, Oriol A.; Gómez-Delgado, Francisco; Jiménez-Lucena, Rosa; García‐Rios, Antonio; Vals-Delgado, Cristina; Romero-Baldonado, Cristina; Luque, Raúl M.; Ordovás, José M.; Pérez‐Martínez, Pablo; Camargo, Antonio; López‐Miranda, José

doi:10.1016/j.clnu.2019.02.027

Cited by 21 publications

(27 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Both studies reported no improvement in glucose regulation. In contrast, Roncero-Ramos et al [ 49 ] found that the Mediterranean diet increased the rate of progression to T2DM compared to a low-fat diet. This study also pointed out that both hepatic insulin resistance and HOMA-IR were not improved.…”

Section: Resultsmentioning

confidence: 94%

“…Twelve studies reported other dietary strategies studied among people with prediabetes. The Mediterranean diet was studied in two trials, which involved 564 participants [ 49 , 106 ]. Both studies reported no improvement in glucose regulation.…”

Section: Resultsmentioning

confidence: 99%

“…Understandably, the most assessed parameter was plasma glucose, often interpreted as FPG and/or two-hour postprandial glucose (2hPG) measured via an oral glucose tolerance test (OGTT). Of 79 studies investigating plasma glucose levels, 48 (60.8%) found significant improvements in one or more of the following categories: FPG, 2hPG and area under the postprandial curve (AUC) over variable timeframes up to 180 min [ 17 , 18 , 19 , 20 , 21 , 23 , 24 , 25 , 26 , 27 , 28 , 31 , 32 , 33 , 37 , 38 , 40 , 41 , 44 , 49 , 50 , 52 , 57 , 58 , 59 , 60 , 61 , 62 , 64 , 65 , 74 , 76 , 78 , 79 , 81 , 85 , 88 , 90 , 93 , 98 , 102 , 103 , 105 , 107 , 108 , 109 , 110 , 111 ]. Likewi...…”

Section: Resultsmentioning

confidence: 99%

“…Among computed values derived from glucose and insulin measurements, the homeostatic model assessment of insulin resistance (HOMA-IR score) was most frequently reported with 41 studies, of which 26 (63.4%) demonstrated significant improvement with intervention [ 17 , 18 , 19 , 21 , 23 , 24 , 28 , 31 , 33 , 36 , 44 , 49 , 53 , 58 , 59 , 62 , 76 , 85 , 86 , 87 , 89 , 93 , 101 , 103 , 109 , 110 ]. A variety of methods were employed by 29 studies to measure insulin sensitivity, namely the Matsuda index, insulin sensitivity index (ISI), quantitative insulin sensitivity check index (QUICKI) and the Cederholm index, and 20 (69.0%) signaled improvement [ 17 , 25 , 27 , 29 , 37 , 49 , 52 , 56 , 58 , 72 , 73 , 74 , 86 , 93 , 94 , 96 , 98 , 99 , 100 , 101 ]. Additionally, significantly better pancreatic β-cell funct...…”

Section: Resultsmentioning

confidence: 99%

“…A variety of methods were employed by 29 studies to measure insulin sensitivity, namely the Matsuda index, insulin sensitivity index (ISI), quantitative insulin sensitivity check index (QUICKI) and the Cederholm index, and 20 (69.0%) signaled improvement [ 17 , 25 , 27 , 29 , 37 , 49 , 52 , 56 , 58 , 72 , 73 , 74 , 86 , 93 , 94 , 96 , 98 , 99 , 100 , 101 ]. Additionally, significantly better pancreatic β-cell function determined via the HOMA-B score as well as the insulinogenic and disposition indices were identified in 12 of 20 studies (60%) [ 17 , 33 , 42 , 49 , 53 , 56 , 74 , 77 , 86 , 89 , 92 , 101 ].…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Nutritional Strategies in Prediabetes: A Scoping Review of Recent Evidence

Yau¹,

Thor²,

Ramadas³

2020

Nutrients

View full text Add to dashboard Cite

Nutritional therapy has been conventionally recommended for people with prediabetes as a method to delay or halt progression to type 2 diabetes. However, recommended nutritional strategies evolve over time. Hence, we performed a scoping review on recently reported nutritional interventions for individuals with prediabetes. Ovid MEDLINE, PubMed, Embase, Scopus, CINAHL and PsycINFO databases were searched to identify relevant research articles published within the past 10 years. Ninety-five articles involving a total of 11,211 participants were included in this review. Nutritional strategies were broadly classified into four groups: low calorie diet, low glycemic index diet, specific foods, and a combination of diet and exercise. The most frequently assessed outcomes were plasma glucose, serum insulin, serum lipid profile, body mass index and body weight. More than 50% of reported interventions resulted in significant improvements in these parameters. Nutritional interventions have demonstrated feasibility and practicality as an effective option for prediabetes management. However, the intervention variability demonstrates the challenges of a ‘one-size-fits-all’ approach. Investigations in genetically diverse populations and objective assessment of progression rate to diabetes are necessary to better comprehend the impact of these nutritional strategies in prediabetes.

show abstract

Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Nutritional Strategies in Prediabetes: A Scoping Review of Recent Evidence

Yau¹,

Thor²,

Ramadas³

2020

Nutrients

View full text Add to dashboard Cite

show abstract

Effects of total fat intake on body fatness in adults

Hooper

Abdelhamid

Jimoh

et al. 2020

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

show abstract

Myricetin ameliorated prediabetes via immunomodulation and gut microbiota interaction

Gao

Gong

et al. 2022

Food Frontiers

View full text Add to dashboard Cite

The global prevalence of prediabetes is on the rise, and it is of value to manage prediabetes and predisposal to diabetes at an early stage. Myricetin is a natural polyhydroxyflavonoid, found in planta with several health benefits. This study aimed to evaluate the effects of myricetin on prediabetes. In vitro assay indicated that the cell viability, endocytosis and phagocytosis of macrophages were inhibited in RAW 264.7 cells under high glucose (HG) levels, concurrent with an increase in reactive oxygen species level. Administration of myricetin at a dose of 10 μM, restored the immunosuppressive effects mediated by HG. Moreover, the viability of Jurkat cells was also inhibited concurrent with inhibition of interleukin-2 (IL-2) and interferon-gamma (IFNγ) expression levels versus increase PD-1 after treated with myricetin at the dose of 10 μM. In a prediabetic mouse model fed with high fat diet, increase in body weight, fat mass, fasting blood glucose, Triglyceride (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were observed. Flow cytometry analysis revealed a significant decrease in CD8 + T cells in the spleen and blood, whereas the expression of PD-1 on CD3 + , CD4 + , and CD8 + T cells in the spleen and lymph was significantly elevated. Administration of myricetin showed a potential hypoglycemic and lipid-lowering effect in both prevention and treatment, in addition to restoration of innate and adaptive immune immunity in mice and confirmed by the in vitro immunomodulation effect. In addition, 16S rRNA showed that myricetin ameliorated prediabetes may be This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

show abstract

Prediabetes diagnosis criteria, type 2 diabetes risk and dietary modulation: The CORDIOPREV study

Cited by 21 publications

References 43 publications

Nutritional Strategies in Prediabetes: A Scoping Review of Recent Evidence

Nutritional Strategies in Prediabetes: A Scoping Review of Recent Evidence

Effects of total fat intake on body fatness in adults

Myricetin ameliorated prediabetes via immunomodulation and gut microbiota interaction

Contact Info

Product

Resources

About