Preconceptional and perinatal exposure to traffic-related air pollution and eczema in preschool children

The interactive effects between air pollution and meteorological factors on the hospital outpatient visits for atopic dermatitis in Beijing, China: a time‐series analysis

“…Although the exact pathogenesis of AD remains unknown, birth cohort studies have suggested that air pollutants such as PM, NO 2 or phthalate may play an important role in AD development . Air pollutants have also been revealed to contribute to the aggravating of pre‐existing AD .…”

“…7 Although the exact pathogenesis of AD remains unknown, birth cohort studies have suggested that air pollutants such as PM, NO 2 or phthalate may play an important role in AD development. [8][9][10][11] Air pollutants have also been revealed to contribute to the aggravating of pre-existing AD. 12,13 In addition, studies of biological mechanism suggested that dust particles and diesel exhaust particulates can exert toxicological effects on human skin.…”

Prenatal particulate matter exposure and wheeze in Mexican children

“…18, 36 In our study, we report associations only during the first trimester of pregnancy, which corresponds to the pseudo-glandular stage of fetal lung development. During this period budding and branching of the tracheobronchial tree is completed and further structural formation of the conducting airways such as vascular, smooth muscle and mucosal glands formation occurs.…”

Early life exposure to environmental pollution increases childhood asthma, allergy and infection

“…一个西班牙出 生队列研究 [40] 发现12~18个月的婴儿湿疹与孕期第 二与第三围产期交通排放污染物NO 2 暴露相关; Hsu 等人 [50] 发现孕期第二围产期PM 2.5 暴露与儿童哮喘显 著相关; 而中国台湾地区的一项近期研究则表明6个 月的婴儿湿疹与孕期第一围产期CO暴露相关 [49] . 本 课题组 [45,51] [31,33] , 还 能够直接导致儿童呼吸系统感染 [64,65] . 通过分析不 同室外空气污染物在不同暴露时期对低龄儿童(3~4 岁)的耳炎影响, 证明了儿童耳炎患病率与出生后空 气污染物暴露无关, 而仅与出生前(孕期)工业排放污 染物SO 2 暴露显著相关, 浓度每增加27 μg/m 3 导致的 耳炎风险OR(95% CI)=1.44(1.09~1.88)(图2) [65] .…”