Precision Target Guide Strategy for Applying SERS into Environmental Monitoring

Ouyang, Lei; Li, Dingyi; Zhu, Lihua; Tang, Heqing

doi:10.5772/64813

Cited by 5 publications

(6 citation statements)

References 93 publications

(110 reference statements)

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“…When the quantity goes over a particular level of fluorescence, this confirms that the virus is present While SERS is using ramen scattering technique that needs single molecule only by selecting the SERS laser on it which gives us a high intensity signals that can be analyzed within minutes as it doesn't need any amplification of the RNA or DNA. [12][13][14][15][16][17][18][19][20][21][22][23] Figure 5 Electromagnetic and chemical enhancement.…”

Section: Resultsmentioning

confidence: 99%

COVID-19 detection using SERS technique

Magdy¹,

Issam²,

Amir³

et al. 2020

MOJABB

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Using Surface-enhanced Raman spectroscopy (SERS) can be a more promising choice for obtaining a faster detection of COVID-19 than the PCR. PCR protocol amplifies the single segment of DNA to 100 billion copies after 40 doubling cycles to provide sufficient intensities of fluorescent signals for virus detection, which takes hours. In this paper, we proposed that the enhanced signals of SERS, which can identify single nucleotide polymorphisms and unique gene sequences, can provide a more economic and accurate detection that does not require the long time needed for DNA amplification of COVID-19. Our proposed diagnostic tool is based on technology of single molecule SERS which checks if the Raman shift of the sample signal matches with the recorded one of COVID-19. In addition, its portability property provides the allowance of its usage in places other than labs and healthcare facilities. Therefore, the superiority of using SERS over fluorescence is manifested in the acquirement of a few-minute detection of coronavirus by the action of a SERS laser rather than the long and expensive measures taken in PCR.

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Section: Resultsmentioning

confidence: 99%

COVID-19 detection using SERS technique

Magdy¹,

Issam²,

Amir³

et al. 2020

MOJABB

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“…The alarming rate of release of these toxic, chemical, and biological wastes thus poses a serious threat to human health and the ecosystem such that waterbodies, soil, air, aquatic species, and the food chain have all come under siege in recent times [2]. Due to the devastating impact of environmental pollutants on human health and the ecosystem, it is imperative and dire to develop rapid and sensitive analytical techniques to aid detection and assessment of the impact of these pollutants [3]. These rapid detection mechanisms could thus serve as and provide an early warning signal to support finding lasting solutions to mitigate and address this menace.…”

Section: Introductionmentioning

confidence: 99%

“…These rapid detection mechanisms could thus serve as and provide an early warning signal to support finding lasting solutions to mitigate and address this menace. Environmental monitoring employing rapid detection requires an effective approach to evaluating pollutants at extremely trace levels by employing highly efficient, sensitive, simple, and rapid analytical tools that can be used for real-life applications [1,3]. Although the gold standard approach and the most widely diverse analytical techniques used for environmental analysis include mass spectroscopy and chromatographic methods, their use for infield applications is hindered due to some drawbacks such as their expensive nature and complex instrumentation systems [4].…”

Section: Introductionmentioning

confidence: 99%

“…The advent of nanomaterials for environmental monitoring processes has broken several limitations of the conventional methods of detecting environmental contaminants as reported in numerous studies. Nanomaterial-based concepts that have been generally explored with promising potential for environmental monitoring include electrochemical sensors, surface plasmon resonance (SPR), and surface-enhanced Raman spectroscopy (SERS) sensing techniques [1][2][3]5].…”

Section: Introductionmentioning

confidence: 99%

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Molecularly Imprinted Plasmonic Sensors as Nano-Transducers: An Effective Approach for Environmental Monitoring Applications

et al. 2023

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Molecularly imprinted plasmonic nanosensors are robust devices capable of selective target interaction, and in some cases reaction catalysis. Recent advances in control of nanoscale structure have opened the door for development of a wide range of chemosensors for environmental monitoring. The soaring rate of environmental pollution through human activities and its negative impact on the ecosystem demands an urgent interest in developing rapid and efficient techniques that can easily be deployed for in-field assessment and environmental monitoring purposes. Organophosphate pesticides (OPPs) play a significant role for agricultural use; however, they also present environmental threats to human health due to their chemical toxicity. Plasmonic sensors are thus vital analytical detection tools that have been explored for many environmental applications and OPP detection due to their excellent properties such as high sensitivity, selectivity, and rapid recognition capability. Molecularly imprinted polymers (MIPs) have also significantly been recognized as a highly efficient, low-cost, and sensitive synthetic sensing technique that has been adopted for environmental monitoring of a wide array of environmental contaminants, specifically for very small molecule detection. In this review, the general concept of MIPs and their synthesis, a summary of OPPs and environmental pollution, plasmonic sensing with MIPs, surface plasmon resonance (SPR), surface-enhanced Raman spectroscopy (SERS) MIP sensors, and nanomaterial-based sensors for environmental monitoring applications and OPP detection have been elucidated according to the recent literature. In addition, a conclusion and future perspectives section at the end summarizes the scope of molecularly imprinted plasmonic sensors for environmental applications.

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“…Compared with fluorescence, IR and other traditional technologies, SERS has many significant advantages, such as its resistance to photo bleaching, high stability and weak Raman signal of water. Therefore, SERS spectroscopy can be widely used in biomedical and chemical analytical science fields, including the detection of protein [6], nucleic acid [7], drugs [8], environmental pollutants [9], and cancer biomarkers [10].…”

Section: Introductionmentioning

confidence: 99%

A Highly Sensitive and Rapid SERS Detection of GSH Based on Hollow Urchin-like Gold Nanoparticles

Zhang¹,

Qian²

2018

dtbh

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Abstract. Glutathione (GSH) plays a key role in many biochemical pathways and the detection of it is of great importance. In this paper, a highly sensitive and rapid detection based on surface-enhanced Raman scattering (SERS) was developed, using the competitive substitution between GSH and p-nitrobenzothiol (PNTP) via the Au-S bond on hollow urchin-like gold nanoparticles (HU-GNPs) surface. By Au-S bond, PNTP could easily connect on HU-GNPs surface, where many branches and edges existed and generated a multitude of "hot spots". Besides, the benzene ring of PNTP also magnified SERS signals. The SERS intensity of PNTP changes was related to the GSH added into the reaction system and there existed linear relationship between SERS intensity and GSH concentrations from 1-10 nM. Owing to its high sensitivity, this method would help to promote the GSH research in biological systems.

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Precision Target Guide Strategy for Applying SERS into Environmental Monitoring

Cited by 5 publications

References 93 publications

COVID-19 detection using SERS technique

COVID-19 detection using SERS technique

Molecularly Imprinted Plasmonic Sensors as Nano-Transducers: An Effective Approach for Environmental Monitoring Applications

A Highly Sensitive and Rapid SERS Detection of GSH Based on Hollow Urchin-like Gold Nanoparticles

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