Precision of Raman depolarization and optical attenuation measurements of sound tooth enamel

Sowa, Michael G.; Popescu, Dan P.; Werner, J.; Hewko, Mark; Ko, Alex C.‐T.; Payette, Jeri R.; Dong, Cecilia C.S.; Cleghorn, Blaine; Choo-Smith, Lin-P’ing

doi:10.1007/s00216-006-0856-9

Cited by 36 publications

(32 citation statements)

References 10 publications

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“…[9 -15] Recently, polarized Raman spectroscopy was used to detect early caries in dental enamel. Co and coworkers [16,17] have shown that sound tooth enamel exhibited strong Raman polarization anisotropy, whereas early caries consistently showed a lower degree of Raman polarization anisotropy. Such decrease in the Raman polarization anisotropy detected in the spectra of carious lesions is believed to be due to structural changes in the enamel rods and/or increased photon scattering resulting from the larger pores within the caries lesions.…”

Section: Introductionmentioning

confidence: 99%

FT‐Raman investigation of human dental enamel surfaces

Mihály

Gombás

Alias

et al. 2009

J Raman Spectroscopy

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FT-Raman spectra of human enamel surfaces from sound, affected (with 1 cavity) and highly affected (with at least 3 cavities) tooth samples were analyzed by principal component analysis (PCA). Major differences between the unaffected and affected tooth samples seem to arise from the structural changes along the c-axis of hydroxyapatite, the chief crystalline component of human dental enamel. Based on Fisher index calculations, the most discriminative value was obtained for the intensity of the only Raman active ν 2 PO 4 3− (E 1 ) symmetric deformation mode at 428 cm −1 . Moreover, these changes can be observed through the whole tooth enamel surface, establishing a predisposition to caries correlated to chemical and structural composition of tooth enamel. No spectral changes regarding the CO 3 2− substitution were detected by both nondestructive FT-Raman and FTIR (Fourier transform infrared) spectroscopy of the powdered teeth samples.

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Section: Introductionmentioning

confidence: 99%

FT‐Raman investigation of human dental enamel surfaces

Mihály

Gombás

Alias

et al. 2009

J Raman Spectroscopy

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“…Consequently, it is highly probable the that signal intensity and signal attenuation coefficient from the sagittal scan can be utilized as objective parameters for the detection of enamel and dentin demineralization. 23,24 This result is relevant in clinical situations, where an occlusal or facial surface can be sagittally imaged by SS-OCT.…”

Section: Discussionmentioning

confidence: 95%

“…Since the signal intensity and attenuation patterns of SS-OCT images are influenced by the presence of caries, attempts were made to utilize the signal intensity and attenuation coefficient as quantitative parameters for the detection of carious. [20][21][22][23][24] However, limited information is available on the potential use of OCT signals. It was suggested that demineralized enamel resulted in a quick and exponential decline of backscatter signal with depth, due to the increased porosity of the tissue.…”

Section: Introductionmentioning

confidence: 99%

Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography

et al. 2016

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, "Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography," J. Med. Imag. 3(3), 035507 (2016), doi: 10.1117/1.JMI.3.3.035507.Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography Abstract. The aim of this study was to evaluate the signal intensity and signal attenuation of swept source optical coherence tomography (SS-OCT) for dental caries in relation to the variation of mineral density. SS-OCT observation was performed on the enamel and dentin artificial demineralization and on natural caries. The artificial caries model on enamel and dentin surfaces was created using Streptococcus mutans biofilms incubated in an oral biofilm reactor. The lesions were centrally cross sectioned and SS-OCT scans were obtained in two directions to construct a three-dimensional data set, from the lesion surface (sagittal scan) and parallel to the lesion surface (horizontal scan). The integrated signal up to 200 μm in depth (IS200) and the attenuation coefficient (μ) of the enamel and dentin lesions were calculated from the SS-OCT signal in horizontal scans at five locations of lesion depth. The values were compared with the mineral density obtained from transverse microradiography. Both enamel and dentin demineralization showed significantly higher IS200 and μ than the sound tooth substrate from the sagittal scan. Enamel demineralization showed significantly higher IS200 than sound enamel, even with low levels of demineralization. In demineralized dentin, the μ from the horizontal scan consistently trended downward compared to the sound dentin.

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“…These models are based on the assumption that the absorption coefficient is very low compared to the scattering coefficient, otherwise their contributions to the signal attenuation cannot be separated, easily. However, the total attenuation coefficient can also contain sufficient information for diagnostic purposes [135][136][137][138].…”

Section: Measurement Of Bulk Optical Propertiesmentioning

confidence: 99%

Optical coherence tomography—current technology and applications in clinical and biomedical research

et al. 2011

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Optical coherence tomography (OCT) is a non-invasive imaging technique providing real-time twoand three-dimensional images of scattering samples with micrometer resolution. Mapping the local reflectivity, OCT visualizes the morphology of the sample. In addition, functional properties such as birefringence, motion or the distribution of certain substances can be detected with high spatial resolution. The main field of application is bio-medical imaging and diagnostics. In ophthalmology, OCT is accepted as a clinical standard for diagnosing and monitoring treatment of a number of retinal diseases, and OCT is becoming an important instrument for clinical cardiology. New applications are emerging in various medical fields, e. g. early-stage cancer detection, surgical guidance, and early diagnosis of musculoskeletal diseases. OCT has also proven its value as a tool for developmental biology. The number of companies involved in manufacturing OCT systems has increased substantially during the last years-especially due to its success in opthalmology-and this technology can be expected to continue to spread into various fields of application.

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Precision of Raman depolarization and optical attenuation measurements of sound tooth enamel

Cited by 36 publications

References 10 publications

FT‐Raman investigation of human dental enamel surfaces

FT‐Raman investigation of human dental enamel surfaces

Optical analysis of enamel and dentin caries in relation to mineral density using swept-source optical coherence tomography

Optical coherence tomography—current technology and applications in clinical and biomedical research

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