Precision of a new ocular biometer in children and comparison with IOLMaster

Abstract

To assess the repeatability and reproducibility of AL-Scan in agreement with those by the IOLMaster in healthy children, two skilled operators measured ocular parameters in 58 children. The parameters included keratometry (K) values, anterior chamber depth (ACD), axial length (AL), central corneal thickness (CCT), pupil diameter (PD), and corneal diameter (CD). The cohort comprised of 32 boys and 26 girls. The AL-Scan measurements showed high repeatability, as the test-retest repeatability (TRT) values of AL, CCT, ACD, Kf, Ks, Km, CD, and PD were 0.09 mm, 5.1 μm, 0.04 mm, 0.28 D, 0.24 D, 0.21 D, 0.39 mm, and 0.22 mm, respectively. The within-subject coefficient of variation (CoV) was low (<0.35%) and the intraclass correlation coefficients (ICC) of all parameters were >0.85. The interobserver reproducibility was excellent with low values of TRT and ICC > 0.95. The CoV of AL, CCT, ACD, and K was <0.22%. The 95% limits of agreement between the AL-Scan and the IOLMaster were narrow for all parameters except for CD. The repeatability and reproducibility of the new biometer, Al-Scan, was excellent for all parameters and can be routinely used in children to measure the biometric values.

Comparison of a New Optical Biometer That Combines Scheimpflug Imaging With Partial Coherence Interferometry With That of an Optical Biometer Based on Swept-Source Optical Coherence Tomography and Placido-Disk Topography

“…To our knowledge, the current study was the first to assess interobserver reproducibility of this new biometer. Our results showed high reproducibility for AL measurements (CoV = 0.09%, ICC=1.000), and was similar to the study using another optical biometer performed by Yu et al ( 21 ) (CoV = 0.09%, ICC = 1.000). Agreement between PCI and SS-OCT for AL was high, with a mean difference of only −0.03 ± 0.03 mm, which was not clinically significant.…”

Clinical Validation of a New Optical Biometer for Myopia Control in a Healthy Pediatric Population

“…These values of Sw found for the keratometry are similar to those reported using the Lenstar LS900 (Haag-Streit AG, Koeniz, Switzerland) biometer in children, around 0.02 mm for both main corneal meridians [ 12 ]. Likewise, the Sw values for the corneal radius reported for the AL-Scan (Nidek Co., Ltd., Gamagori, Japan) and the IOL Master 700 (Carl Zeiss Meditec AG, Jena, Germany) devices were between 0.08 D and 0.11 D in children [ 13 , 14 ]. In the present study, the Sw for the keratometry (K1 and K2), calculated in terms of refractive power, would be of 0.10 D, approximately, a value comparable to that reported using the IOL Master 700 device.…”

Comparison of axial length using a new swept-source optical coherence tomography-based biometer - ARGOS with partial coherence interferometry- based biometer -IOLMaster among school children

“…All of the above mentioned studies were done on adults and to the best of our knowledge this is the first study to look at the agreement of these two non contact biometers among children. Among the pediatric population, a recent study by Chen et al [18] compared axial length, anterior corneal curvature and anterior chamber depth measurements between IOL Master and AL- Scan (Nidek Co.,). The mean difference in AL was close to zero (LoA -0.05 to 0.05) and the mean difference in keratometry was reported to be -0.13D (LoA -0.37 to 0.10).…”