Precise Measurement of Vertebral Mineral Content Using Computed Tomography

Cann, Christopher E.; Genant, Harry K.

doi:10.1097/00004728-198008000-00018

Cited by 517 publications

(178 citation statements)

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“…Hounsfield unit (CTHU)-based QCT technique has been utilized over the last three decades [3,6]. Lumbar QCT was the only method initially [6].…”

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

“…Lumbar QCT was the only method initially [6]. With this technique, the CT image was obtained using routine scan parameters in the lumbar spine with a calibration phantom under the patient's back.…”

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

“…With this technique, the CT image was obtained using routine scan parameters in the lumbar spine with a calibration phantom under the patient's back. Lower radiation dose protocol was used in most studies, such as 80kVp/140 mAs or 140 kVp/80 mAs with 5 mm image thickness or greater [6,15]. The calibration phantom technique has two functions, translating the CTHU to the bone units (mg/mm 3 ) and calibrating CTHU within location, patients and scanners made by many manufacturers.…”

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

“…The calibration phantom technique has two functions, translating the CTHU to the bone units (mg/mm 3 ) and calibrating CTHU within location, patients and scanners made by many manufacturers. The calibration standard was originally designed by Cann et al [6] (Mindway, South San Francisco, CA, USA). Subsequently, two standard phantoms were also used commonly, developed by the Image analysis, (Columbia, KY, USA) [16] and Siemens Medical System [17] (Erlangen, Germany).…”

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

“…Since then, DXA has been widely used for the epidemiological studies, clinical research and treatment strategies of osteoporosis [4,5]. Lumbar QCT had been employed in the 1980s [6], is also recommended as an acceptable method in the diagnosing osteoporosis by the WHO. A certain number of new technologies have been developed for assessing bone mineral density until now, including peripheral QCT (pQCT) [7], μCT (microCT) [8], magnetic resonance imaging (MRI) [9,10] and quantitative ultrasound (QUS) [11].…”

Section: Introductionmentioning

confidence: 99%

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Application of quantitative computed tomography for assessment of trabecular bone mineral density, microarchitecture and mechanical property

et al. 2016

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a b s t r a c t a r t i c l e i n f oOsteoporosis is a common metabolic bone disease, causing increased skeletal fragility characterized by a low bone mass and trabecular microarchitectural deterioration. Assessment of the bone mineral density (BMD) is the primary determinant of skeletal fragility. Computed tomography (CT)-based trabecular microarchitectural and mechanical assessments are important methods to evaluate the skeletal strength. In this review, we focus the feasibility of QCT BMD measurement using a calibration phantom or phantomless. The application of QCT could extend the bone mineral density assessment to all patients who underwent a heart, lung, whole-body, and as well as all routine clinical implications of CT scan.

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“…Hounsfield unit (CTHU)-based QCT technique has been utilized over the last three decades [3,6]. Lumbar QCT was the only method initially [6].…”

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%

Section: Qct Technique In the Lumbar Spinementioning

confidence: 99%