Precipitation of the Specific Polysaccharide of Cryptococcus neoformans A by Types II and XIV Antipneumococcal Sera¹

Long-lasting, specific immunologic unresponsiveness associated with cryptococcal meningitis.

“…Both the patients and the controls significantly elevated IgA, IgG, and IgM titers against SSSIII (Fig. 3) (6,14,15). Similar experience has been encountered with normal humans having antibody to dextran (16), to melibiose (17), and to certain microbial polysaccharides (18).…”

The Use of Fluorescein-Labelled Lectins in the Detection and Identification of Fungi Pathogenic for Man: A Preliminary Study

“…The serological type of the organism used here was not known. In types A and B a little galactose is present (Drouhet, Segretain and Aubert, 1950;Evans and Kessel, 1951;Evans and Mehl, 1951;Evans and Theriault, 1953;Rebers et al, 1958;Blandamer and Danishefsky, 1966), but if it were not terminal it would not react with FL-RCA; this might explain the lack of staining with FL-RCA.…”

Chemical Characterization of Capsular Polysaccharide from Cryptococcus neoformans Serotype A‐D

“…After partial hydrolysis of the polysaccharide with 0.5 M TFA, the acidic fraction was separated from the neutral proposed the chemical structure of a polysaccharide composed of mannose, xylose, and glucuronic acid. On the other hand, Rebers et al (27) reported that C. neoformans possesses at least two polysaccharides at the cell surface on the basis of differential precipitation of a polysaccharide moiety with a higher galactose to mannose ratio with anti-type XIV pneumococcal antiserum. Recently, Turner et al (31) showed that C. neoformans serotype D polysaccharide could be separated into glucuronoxylomannan and galactoxylomannan.…”