Pre-launch performance characterization of EOS-C camera

Choi, Young‐Wan; Kang, Shaozhong; Yun, Ji-Ho; Jongun, Kim; Kang, Minho; Jeong, Sung-Keun; Kim, Hyun-Gu; Song, Jaehun; Kim, Ee-Eul

doi:10.1117/12.794873

Cited by 1 publication

(2 citation statements)

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“…Recently, several reports have demonstrated that BLT2 is critical for NOX upregulation. For example, the induced expression of BLT2 by oncogenic H-Ras results in the generation of ROS via NOX1 upregulation (Choi et al, 2008). Previous studies have also demonstrated that the LTB 4 -BLT2-NOX1-linked cascade plays a critical role in the invasive and metastatic activity that is associated with oncogenic H-Ras (Choi et al, 2008;Kim et al, 2010a).…”

Section: Blt1/blt2 and Noxmentioning

confidence: 99%

“…For example, the induced expression of BLT2 by oncogenic H-Ras results in the generation of ROS via NOX1 upregulation (Choi et al, 2008). Previous studies have also demonstrated that the LTB 4 -BLT2-NOX1-linked cascade plays a critical role in the invasive and metastatic activity that is associated with oncogenic H-Ras (Choi et al, 2008;Kim et al, 2010a). In addition, increased ROS generation appears to play an important role in maintaining cancer phenotypes due to the stimulating effects of ROS on cell growth and proliferation (Hu et al, 2005).…”

Section: Blt1/blt2 and Noxmentioning

confidence: 99%

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Bioactive Lipoxygenase Metabolites Stimulation of NADPH Oxidases and Reactive Oxygen Species

Cho

Seo

Kim

2011

Molecules and Cells

155

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In mammalian cells, reactive oxygen species (ROS) are produced via a variety of cellular oxidative processes, including the activity of NADPH oxidases (NOX), the activity of xanthine oxidases, the metabolism of arachidonic acid (AA) by lipoxygenases (LOX) and cyclooxygenases (COX), and the mitochondrial respiratory chain. Although NOX-generated ROS are the best characterized examples of ROS in mammalian cells, ROS are also generated by the oxidative metabolism (e.g., via LOX and COX) of AA that is released from the membrane phospholipids via the activity of cytosolic phospholipase A 2 (cPLA 2 ). Recently, growing evidence suggests that LOX-and COX-generated AA metabolites can induce ROS generation by stimulating NOX and that a potential signaling connection exits between the LOX/COX metabolites and NOX. In this review, we discuss the results of recent studies that report the generation of ROS by LOX metabolites, especially 5-LOX metabolites, via NOX stimulation. In particular, we have focused on the contribution of leukotriene B 4 (LTB 4 ), a potent bioactive eicosanoid that is derived from 5-LOX, and its receptors, BLT1 and BLT2, to NOX stimulation through a signaling mechanism that leads to ROS generation.

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Section: Blt1/blt2 and Noxmentioning

confidence: 99%