2019
DOI: 10.18231/j.ijcaap.2019.004
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Pre-clinical evaluation of hepatoprotective activity of phytol in wistar albino rats

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Cited by 9 publications
(5 citation statements)
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“…demonstrated the hepatoprotective activity of phytol in the ethanol-induced liver injury in rats. These authors suggested that phytol can be used as hepatoprotective agent as an alternate to silymarin . Moreover, research findings indicated that coumarin and its derivatives exert protective effects which reduce oxidative stress and inhibit apoptotic cell death…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…demonstrated the hepatoprotective activity of phytol in the ethanol-induced liver injury in rats. These authors suggested that phytol can be used as hepatoprotective agent as an alternate to silymarin . Moreover, research findings indicated that coumarin and its derivatives exert protective effects which reduce oxidative stress and inhibit apoptotic cell death…”
Section: Discussionmentioning
confidence: 99%
“…These authors suggested that phytol can be used as hepatoprotective agent as an alternate to silymarin. 49 Moreover, research findings indicated that coumarin and its derivatives exert protective effects which reduce oxidative stress and inhibit apoptotic cell death. 50 In a similar fashion, Sivakrishnan and Muthu evaluated the hepatoprotective activity of squalene isolated from Albiziaprocera against paracetamol-induced hepatotoxicity in Wistar rats.…”
Section: Chemical Research In Toxicologymentioning
confidence: 99%
“…For instance, oleic acids ameliorated hepatocellular lipotoxicity both in vitro and in vivo by inhibiting endoplasmic reticulum stress and pyroptosis (Zeng et al 2020 ). Also, phytol showed significant hepatoprotective activity in the ethanol-induced pharmacological animal model (Gupta et al 2019 ).…”
Section: Discussionmentioning
confidence: 99%
“…Phytol is a natural linear diterpene fatty alcohol present in an integral part of chlorophyll. The possible mechanism behind the hepatoprotection of phytol was might be due to its antioxidant activity, free radical scavenging activity, and synergistic effect [20].…”
Section: Discussionmentioning
confidence: 99%