Pre-breeding beef heifer management and season affect mid to late gestation uterine artery hemodynamics

Cain, A. J.; Lemley, Caleb O; Walters, Field; Christiansen, David L.; King, E. H.; Hopper, Richard M.

doi:10.1016/j.theriogenology.2016.07.031

Cited by 6 publications

(2 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Seasonality appears to affect female reproduction in several ways, including cyclicity, conception, uterine blood flow, and offspring performance, which may be due to photoperiod, weather, or a combination of these environmental factors. In a study by Cain et al [18], spring calving beef heifers had increased uterine blood flow during gestation and heavier calves at birth compared to fall calving heifers. Conversely, in a study by King and Macleod [19], postpartum fall calving cows returned to cyclicity and became pregnant earlier than spring calving cows.…”

Section: Discussionmentioning

confidence: 98%

Melatonin Supplementation Alters Maternal and Fetal Amino Acid Concentrations and Placental Nutrient Transporters in a Nutrient Restriction Bovine Model

et al. 2022

View full text Add to dashboard Cite

Melatonin rescues uterine blood flow and fetal body weight in a seasonal dependent manner within a nutrient restriction bovine model. We sought to identify the effects of nutrient restriction, melatonin, and sampling time on maternal and fetal amino acids, and placental nutrient transporters. Pregnant heifers received adequate or restricted nutrition, and 20 mg of melatonin or placebo from gestational days 160–240 over two seasons. On day 240 maternal and fetal blood, amnion, and placentomes were collected. Amino acid concentrations were determined by gas chromatography-mass spectrometry. Caruncle and cotyledon tissues were assessed for nutrient transporter density by qPCR. Data were analyzed using the MIXED procedure of SAS for fixed effects. In fall, melatonin rescued effects of nutrient restriction on System N, Anion, and total maternal amino acids. Furthermore, melatonin rescued effects of nutrient restriction on Systems A, N, Br, Bo, and essential amnion amino acids. In summer, melatonin rescued effects of nutrient restriction in Systems Br and Bo maternal amino acids. Furthermore, melatonin rescued effects of nutrient restriction on caruncle SLC38A10 and SLC38A2. Melatonin rescued effects of nutrient restriction in a seasonal dependent manner. These data align with previous studies suggesting melatonin is a more effective therapeutic in summer months.

show abstract

Section: Discussionmentioning

confidence: 98%

Melatonin Supplementation Alters Maternal and Fetal Amino Acid Concentrations and Placental Nutrient Transporters in a Nutrient Restriction Bovine Model

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In comparison to sheep, the developing bovine fetus is more susceptible to alterations in myogenesis and adipogenesis when subjected to maternal nutrient restriction during mid- to late-gestation ( Greenwood and Café, 2007 ) whereas nutritional restrictions during early pregnancy can have subtle effects on organogenesis, causing long-term health complications ( Greenwood and Bell, 2003 ; Bell et al ., 2005 ). Pre-breeding management of heifers influenced uterine hemodynamics as low input (fed to 45 to 55% of mature body weight at breeding) females had increased uterine blood flow (adjusted for maternal body weight) compared to conventionally fed heifers, with authors hypothesizing the increased uterine blood flow compensated for inadequate heifer body reserves ( Cain et al ., 2017 ; Table 2 ).…”

Section: Nutrient Restriction In the Beef Cowmentioning

confidence: 99%

Effect of maternal diet on placental development, uteroplacental blood flow, and offspring development in beef cattle

Vonnahme¹,

Tanner²,

Hildago³

2018

Anim Reprod

View full text Add to dashboard Cite

Considerable effort has been made to understand how nutrition influences livestock health and productivity during the postnatal period. Moreover, while efforts have been made to understand how nutrition impacts many different aspects of female reproduction, there is a growing body of literature that focuses on how maternal nutrition impacts the developing fetus. Providing adequate nutrition during pregnancy is important for maternal health and wellbeing, as well as conceptus development. Proper establishment of the placenta is important for fetal survival. However, placental adaptations to inadequate maternal nutrition, or other stressors, are imperative for fetal growth to be optimal. By understanding how the maternal environment impacts uterine and umbilical blood flows and other uteroplacental hemodynamic parameters, we can better implement supplementation strategies to protect the developing offspring. This review focuses on how maternal nutrition affects conceptus growth in sheep and beef cattle and offspring performance after birth.

show abstract

Fetal Programming

Lemley¹,

Littlejohn²,

Burnett³

2021

Bovine Reproduction

View full text Add to dashboard Cite

Pre-breeding beef heifer management and season affect mid to late gestation uterine artery hemodynamics

Cited by 6 publications

References 39 publications

Melatonin Supplementation Alters Maternal and Fetal Amino Acid Concentrations and Placental Nutrient Transporters in a Nutrient Restriction Bovine Model

Melatonin Supplementation Alters Maternal and Fetal Amino Acid Concentrations and Placental Nutrient Transporters in a Nutrient Restriction Bovine Model

Effect of maternal diet on placental development, uteroplacental blood flow, and offspring development in beef cattle

Fetal Programming

Contact Info

Product

Resources

About