Pravastatin treatment before coronary artery bypass grafting for reduction of postoperative atrial fibrillation

Abstract

Pravastatin treatment before CABG may decrease the incidence of postoperative AF.

Inflammation in new‐onset atrial fibrillation after cardiac surgery: a systematic review

“…Fifteen cohort studies [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] and six RCTs [42][43][44][45][46][47] evaluated the effect of preoperative and postoperative statins on preventing PNAF. Of the 15 cohort studies, ten studies found that statins prevented PNAF [24,27,31,33,36]. On the contrary, four studies showed no effect on PNAF [25,26,34,35].…”

Effect of Statins on the Incidence of Postoperative Atrial Fibrillation after Cardiac Valve Surgery

“…Similar to statin dose, the specific statin medication was not recorded in our institution's database. One trial found a beneficial effect on POAF with pravastatin but not with atorvastatin. Other studies, however, have not found a difference between specific statin medications and the incidence of POAF .…”

Statin therapy in the prevention of atrial fibrillation in the early postoperative period after coronary artery bypass grafting: A meta-analysis

“…Among them, 5598 (59.75%) patients were taking statins and 3771 (40.25%) patients were not taking statins. The characteristics of studies included in the meta-analysis are presented in Table 1 [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31].…”