Abstract:Primary open angle glaucoma (POAG) is usually a chronic, slowly progressive disease. At present, all
resources are directed towards reduction of intraocular pressure (IOP), the only known causal and treatable
risk factor for glaucoma, and medical management is frequently the first choice in most cases. With the
introduction of innovative tools for early diagnosis and newer medications for treatment, decision-making in
diagnosis and treatment of glaucoma has become more complex. The philosophy of glaucoma manag… Show more
“…A study that evaluated these QOL issues categorized patients mainly into two groups based on their main priorities as “reading and seeing detail” and “outdoor mobility”, the latter changing to the former with increasing visual field loss and an increased willingness to trade time off for therapy thus resulting in a situation of forced compliance (Aspinall et al 2008). Considering this, it is remarkable how, the entire viewpoint of treating glaucoma has gradually changed to preserving “visual function” while ensuring minimal effects on QOL in terms of cost, treatment regime, follow-up schedules as well as socio economic burden (Janz et al 2001; Parikh et al 2008). …”
Section: Treatment Decisions and Effects On Quality Of Lifementioning
Primary open angle glaucoma is a chronic optic neuropathy often requiring lifelong treatment. Patient compliance, adherence and persistence with therapy play a vital role in improved outcomes by reducing morbidity and the economic consequences that are associated with disease progression. A literature review including searches of The Cochrane Library, MEDLINE, PubMed, conference proceedings, and bibliographies of identified articles reveals the enormous public health burden in various populations due to the impact of glaucoma associated visual impairment on the overall quality of life eg, fear of blindness, inability to work in certain occupations, driving restrictions, motor vehicle accidents, falls, and general health status. Providing specific definitions for the frequently misunderstood terms “compliance, persistence and adherence” with reference to medication use is central not only for monitoring patients’ drug dosing histories and clinical outcomes but also for subsequent research. In this review article, a summary of the advantages/disadvantages including cost-effectiveness of various medical approaches to glaucoma treatment, techniques employed for measuring patient compliance and actual patient preferences for therapy are outlined. We conclude by identifying the key barriers to ongoing treatment and suggest some best practices to enhance compliance and persistence.
“…A study that evaluated these QOL issues categorized patients mainly into two groups based on their main priorities as “reading and seeing detail” and “outdoor mobility”, the latter changing to the former with increasing visual field loss and an increased willingness to trade time off for therapy thus resulting in a situation of forced compliance (Aspinall et al 2008). Considering this, it is remarkable how, the entire viewpoint of treating glaucoma has gradually changed to preserving “visual function” while ensuring minimal effects on QOL in terms of cost, treatment regime, follow-up schedules as well as socio economic burden (Janz et al 2001; Parikh et al 2008). …”
Section: Treatment Decisions and Effects On Quality Of Lifementioning
Primary open angle glaucoma is a chronic optic neuropathy often requiring lifelong treatment. Patient compliance, adherence and persistence with therapy play a vital role in improved outcomes by reducing morbidity and the economic consequences that are associated with disease progression. A literature review including searches of The Cochrane Library, MEDLINE, PubMed, conference proceedings, and bibliographies of identified articles reveals the enormous public health burden in various populations due to the impact of glaucoma associated visual impairment on the overall quality of life eg, fear of blindness, inability to work in certain occupations, driving restrictions, motor vehicle accidents, falls, and general health status. Providing specific definitions for the frequently misunderstood terms “compliance, persistence and adherence” with reference to medication use is central not only for monitoring patients’ drug dosing histories and clinical outcomes but also for subsequent research. In this review article, a summary of the advantages/disadvantages including cost-effectiveness of various medical approaches to glaucoma treatment, techniques employed for measuring patient compliance and actual patient preferences for therapy are outlined. We conclude by identifying the key barriers to ongoing treatment and suggest some best practices to enhance compliance and persistence.
“…[5] With the introduction of innovative tools for early diagnosis and newer medications for treatment, diagnosis and treatment of glaucoma has became more complex. [6] The newer glaucoma medications have advantages like increased efficacy, reduced dosing frequency, and improved side effect profile. Studies related to drug utilization in glaucoma reported from India are scarce.…”
Objective:To study drug use pattern in patients of primary open angle glaucoma (POAG) and to analyze the cost of different anti-glaucoma medications.Materials and Methods:This prospective study was carried in the glaucoma clinic of a tertiary care teaching hospital over a period of 9 months. The data collected for patients with POAG included the patient's demographic details and the drugs prescribed. Data were analyzed for drug use pattern and cost drugs used.Results:In a total 180 prescriptions (297 drugs) analyzed, most drugs (83.83%) were prescribed by topical route as eye drops. β blockers (93.88%) were found to be the most frequently prescribed for POAG. Timolol (82.22%) was the most frequently prescribed drug and timolol with acetazolamide (17.22%) was the most commonly prescribed drug combination. Fixed dose combinations constituted 26.66% of prescriptions. β blockers were found to be cheaper than other anti-glaucoma drugs while prostaglandins analogs were the costliest. Instructions about the route, frequency and duration of treatment were present in all prescriptions. However, instructions regarding instillation of eye drops were missing in all prescriptions.
“…In our own clinical routine: we use the "Overview" and glaucoma progression analysis (GPA) programs. 3 Eyeballing the overview we get a feel for whether field deterioration is due to generalized sinking of the hill of vision or whether it is due to glaucoma. GPA is based on the pattern deviation plot and is better option to diagnose progression.…”
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