Drug use in primary open angle glaucoma: A prospective study at a tertiary care teaching hospital

Yadav, Arvind Kumar; Patel, Varsha J.

doi:10.4103/0253-7613.108279

Cited by 20 publications

(39 citation statements)

References 15 publications

(17 reference statements)

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“…10 Most common variant of glaucoma in this study is Primary open angle glaucoma and this result is consistent with similar kind of study. 11 Average number of drugs per prescription was 2 (45%) in our study, justifying on basis of such recommendation. 12 Majority of patients in this study were treated with Fixed Dose Combination of Brimonidine+Timolol and most common drug as monotherapy was Tab.…”

Section: Discussionsupporting

confidence: 72%

A drug utilization study in glaucoma patients in ophthalmology out patient department in a tertiary care hospital

Patel

Dumra

Singh

et al. 2017

Int J Basic Clin Pharmacol

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Background: According to World Health Organization (WHO) studies Glaucoma is a chronic progressive symptomatic disease that damages retinal cells and is one of the leading cause of preventable blindness worldwide. Availability of newer topical agents has modernized the management of glaucoma.Methods: A prospective observational study was carried out from August 2016 to December 2016 at ophthalmology Out Patient Department of L.G General Hospital, Ahmedabad by authours after the approval of the Institutional Ethics Committee.Results: Out of total 101 patients, 71 were males and 30 were females. Average age of patient is 54 years. Common variant of Glaucoma was Primary Open Angle Glaucoma in 57.4% of patients. Average number of drugs per prescription was 2 (45%). Most commonly used Fixed Dose Combination was Brimonidine +Timolol Drops which was used in 87 (86.1%) patients. Most commonly used adjuvant drug was Tab. Acetazolamide (60% of patients).Conclusions: Common variant of Glaucoma was Primary Open Angle Glaucoma in 57.4% of patients. Most commonly used Fixed Dose Combination was Brimonidine+Timolol Drops which was used in 87 (86.1%) patients and commonly used Single drug therapy is Tab. Acetazolamide in (60% of patients).

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Section: Discussionsupporting

confidence: 72%

A drug utilization study in glaucoma patients in ophthalmology out patient department in a tertiary care hospital

Patel

Dumra

Singh

et al. 2017

Int J Basic Clin Pharmacol

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“…The predominance reliance on monotherapy and particularly the use of Timolol is uncommon in similar studies [12, 24]. In this study, this can be attributed to a preference for low-priced medication, its availability on the NHIS medication list, and prescriber preference which perhaps is due to the uncomplicated nature of administering it alone or in combination with other class of glaucoma medications [14, 25–28].…”

Section: Discussionmentioning

confidence: 74%

Cost of the medical management and prescription pattern for primary open angle glaucoma (POAG) in Ghana–a retrospective cross-sectional study from three referral facilities

Ocansey

Kyei

Diafo

et al. 2016

BMC Health Serv Res

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BackgroundGlaucoma is the leading cause of irreversible blindness globally, and treatment involves considerable cost to stakeholders in healthcare. However, there is infrequent availability of cost information and patterns of management, especially in developing countries. This study determined the cost of the medical management of POAG, adherence, and pattern of medication prescription in Ghana.MethodsA retrospective cross-sectional study involving 891 Primary Open Angle Glaucoma (POAG) cases seen in the year 2012 at three referral facilities. Demographics, ocular history, resource consumption, medication, test, surgery and other related cost were extracted from 84 patients who had fully complied with their treatment to calculate total cost (TC) based on 2012 estimates. Glaucoma drugs prescribed to patients who had adhered to all their review visits within the period evident from case folders were recorded and analysed for the prescription pattern.ResultsOut of 891 POAG cases seen in 2012, 351(39.4 %) attended all the required review visits, but only 84 (9.4) had fully and continually adhered to all their treatment regimes. They comprised 41(48.8 %) males and 43(51.2 %) females with a mean age of 65 ± 14.8. Majority of the respondents were elderly above 60 year of age (65.5 %). The total estimated cost for the 84 cases in the year was GH¢ 81,237 ($40,619), comprising GH¢ 72,193 ($36,097) direct medication cost and GH¢9,045 ($4,523) direct non-medication cost (surgery and test cost), and an average of GH¢ 967 ($484) for a mean visit of 5.6 ± 1.1 in the year. A total of 673 glaucoma medications had been prescribed for 351 patients for the year, with timolol being the most prescribed (64.19 %) and monotherapy as the most adopted form of therapy (61.06 %). Age and income showed concurrent increase with cost (P ≤ 0.05).ConclusionsCost of managing glaucoma constitutes a substantial financial burden and influenced the pattern of medication prescription.

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“…Glaucoma is a condition that involves distinctive changes in the optic nerve and visual field [1]. It is marked by raised intraocular pressure (IOP) that compresses and damages the optic nerve.…”

Section: Introductionmentioning

confidence: 99%

To Study the Drug Use Pattern in Primary Open Angle Glaucoma in a Tertiary Care Teaching

Deepalatha¹,

Mb²

2017

Asian J Pharm Clin Res

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Objective: To study the drug utilization pattern in patients suffering from primary open-angle glaucoma (POAG) in a tertiary care teaching hospital. Methods:It is a prospective study done on 50 patients of POAG (comprising of individuals belonging to any age group). This study was carried for a period of 2-month, and the data included patient's demographic details and the drugs prescribed. Data were analyzed for drug use pattern.Results: After screening the prescriptions of patients, it was found out that out of total 50 prescriptions, 30 were males, and 20 were females. Out of 50 prescriptions, prostaglandins (58%) were most commonly prescribed. β-blockers (16%) were also prescribed. Fixed dose combination constituted 60% of the prescriptions. Instructions about the route, frequency, and duration of treatment were present in all prescriptions. Drugs prescribed by their generic names were 18.75% and about 81.25% of the drugs were prescribed by their brand names. Conclusions:Fixed drug combination of timolol and dorzolamide was the most frequently prescribed combination. Prescribers must be aware of importance of prescribing drugs with generic names.

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Drug use in primary open angle glaucoma: A prospective study at a tertiary care teaching hospital

Cited by 20 publications

References 15 publications

A drug utilization study in glaucoma patients in ophthalmology out patient department in a tertiary care hospital

A drug utilization study in glaucoma patients in ophthalmology out patient department in a tertiary care hospital

Cost of the medical management and prescription pattern for primary open angle glaucoma (POAG) in Ghana–a retrospective cross-sectional study from three referral facilities

To Study the Drug Use Pattern in Primary Open Angle Glaucoma in a Tertiary Care Teaching

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