Potentially toxic elements in freshwater (Alburnus spp.) and marine (Sardina pilchardus) sardines from the Western Balkan Peninsula: An assessment of human health risk and management

Milošković, Aleksandra; Milošević, Đurađ; Radojković, Nataša; Radenković, Milena; Đuretanović, Simona; Veličković, Tijana; Simić, Vladica

doi:10.1016/j.scitotenv.2018.07.041

Cited by 15 publications

(8 citation statements)

References 30 publications

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“…Considering the low levels of contaminant elements in fish samples, developing sensitive analytical procedures able to accurately determine trace elements mass fractions is essential in order to ensure an effective seafood safety control. To date, many analytical techniques for trace elements determination in marine biota have been reported, including: Atomic Absorption Spectrometry (Metian et al 2013;Bandowe et al 2014;Burger et al 2014;Goutte et al 2015;Bay et al 2017;Chouvelon et al 2017;Łuczyńska et al 2018;Bilandžić et al 2018;Zuliani et al 2019;Plessl et al 2019), Inductively Coupled Plasma Optical Emission Spectrometry (Jooste et al 2015;Goutte et al 2015;Ourgaud et al 2017;Milošković et al 2018) and Inductively Coupled Plasma-Mass Spectrometry (Goutte et al 2015;Squadrone et al 2016;Chouvelon et al 2017;Ourgaud et al 2017;Bilandžić et al 2018;Sofoulaki et al 2019;Zuliani et al 2019).…”

Section: Introductionmentioning

confidence: 99%

Reference Measurements for Priority and Essential Trace Elements and Methyl Mercury with Isotope Dilution Inductively Coupled Plasma-Mass Spectrometry for Seafood Safety Assessment and CRM Production

et al. 2019

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The continuous release of anthropogenic pollutants into marine environment increase the needs for the development of analytical procedures for their accurate determination in many sample types. Sound strategies for seafood safety monitoring call for measurement systems capable of producing comparable analytical results with demonstrated quality. Method validation, traceability and uncertainty of analytical results are the three milestones to assess data quality. Some trace elements are essential for biological structures, but they can become toxic at concentrations beyond those necessary for their functions; others, are toxic even at very low levels. Their accurate determination in reference samples serves as an important step in seafood safety control and pollution monitoring.Isotope Dilution Inductively Coupled Plasma Mass Spectrometry (ID ICP-MS) has been applied for the determination of the total mass fractions of five trace elements (Cd, Cu, Hg, methyl mercury (MeHg), Pb, and Zn) in marine biota candidate reference material IAEA-476. Because of the complex matrix of the sample and the expected spectral interferences, special care was taken for the validation of the applied methodology, particularly for its measurement step. Reference isotopic measurements were carried out by Sector Field Inductively Coupled Plasma Mass Spectrometer (ICP-SFMS).The entire ID ICP-SFMS measurement procedure was described by mathematical modelling and the combined uncertainty of measurement results estimated. All factors influencing the final results and isotopic equilibrium were systematically investigated. This included the procedural blank, the moisture content in biota samples and all factors affecting the blend ratio measurements (i.e., instrumental background, spectral interferences, dead time, mass discrimination effects as well as the repeatability of measured isotope ratios).Modeling of the entire measurement procedure and the use of appropriate certified reference materials (CRM) enable to assure the traceability of obtained values to the International System of Units (SI).Finally, the developed procedure has been successfully applied in the process of the certification of the International Atomic Energy Agency (IAEA) certified reference material for trace elements and MeHg mass fractions in fish homogenate sample. The excellent agreement between obtained results in the present study and those derived from the IAEA certification campaign for trace elements and MeHg in the same sample matrix further validated the reference methods developed in the IAEA.

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Section: Introductionmentioning

confidence: 99%

Reference Measurements for Priority and Essential Trace Elements and Methyl Mercury with Isotope Dilution Inductively Coupled Plasma-Mass Spectrometry for Seafood Safety Assessment and CRM Production

et al. 2019

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“…Due to heavy metals being widely spread in the environment, it is essential to hygienically assess heavy metals contents, both in food products and drinking water [4][5][6][7]. When exposure to contaminants in food products and drinking water is determined, it allows not only to identify probable outcomes for population health but also to indirectly trace migration routes for examined alien chemicals in the environment [8][9][10][11]. Previous research that focused on hygienic assessment of heavy metals and microelements in environmental objects substantiates a biochemical province concept and makes it necessary to explore peculiarities and essence of inter-media migration taking into account regional peculiarities [12][13][14][15].…”

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confidence: 99%

Hygienic assessment of population health risks caused by combined oral introduction of heavy metals

Boev¹,

Kryazhevа²,

Бегун³

et al. 2019

Health Risk Analysis

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There is a pressing issue related to combined oral introduction of heavy metals into a human body with drinking water and food products. It is caused by food products contamination, very high probability that metals migrate into water and plants from soils, ambient air, etc. The research goal was to hygienically assess combined oral introduction of heavy metals with drinking water and food products with subsequent population health risks assessment. The authors analyzed long-term data on structure and volumes of food products consumption and assessed population exposure under combined oral introduction of heavy metals (mercury, cadmium, arsenic, and lead) contained in drinking water and food products. Data were obtained from a regional information social-hygienic monitoring database and a regional office of the Federal Statistics Service. Both regional products and products delivered from other regions (or countries) were analyzed. It was detected that population in the region consumed food products per 1 person a year in a quantity which was by 93 kg higher than on average in the country. Calculated concentrations of the examined substances in food products and drinking water corresponded to hygienic standards. Dairy products had the first rank place as regards a contribution made into the overall exposure to lead, cadmium, and arsenic. The second and the third place belonged to vegetables and melons and grocery respectively. The first rank place as per a contribution made into the overall exposure to mercury belonged to vegetables and melons; the second place, to grocery; the third place, to dairy products. Non-carcinogenic risk assessment revealed that hazard quotients related to heavy metals contents in food products and drinking water were within acceptable risks limits. Total carcinogenic risk (TCR) was unacceptable (1.5Е-03.). A number of additional oncologic diseases in the region could reach 557 cases (during 70 years) under the worst scenario.

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“…В связи с широким распространением в окружающей среде тяжелых металлов особенно актуальной и своевременной является задача по гигиенической оценке тяжелых металлов как в продуктах питания, так и в питьевой воде [4][5][6][7]. Определение экспозиции от контаминантов в продуктах питания и питьевой воде позволяет не только выявить возможные последствия для здоровья населения, но и косвенно отследить путь миграции исследуемых чужеродных химических веществ в окружающей среде [8][9][10][11]. Ранее проведенные исследования по гигиенической оценке тяжелых металлов и микроэлементов в объектах окружающей среды обусловливают концепцию биогеохимических провинций и создают необходимость изучения особенностей и характера межсредовой миграции с учетом региональных особенностей [12][13][14][15].…”

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Hygienic assessment of population health risks caused by combined oral introduction of heavy metals

Boev¹,

Kryazheva²,

Бегун³

et al. 2019

Health Risk Analysis

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Проблема комбинированного перорального поступления тяжелых металлов с питьевой водой и пищевыми продуктами в организм человека является актуальной. Это связано с контаминацией продуктов, с большой вероятностью миграции металлов в воду и растения из почвы, атмосферного воздуха и т.п. Целью научного исследования явилась гигиеническая оценка комбинированного перорального поступления тяжелых металлов с питьевой водой и продуктами питания с последующей оценкой риска для здоровья населения. В работе проанализированы многолетние данные о структуре, объеме потребления продуктов и проведена оценка экспозиции населения при комбинированном пероральном поступлении тяжелых металлов (ртуть, кадмий, мышьяк, свинец), содержащихся в питьевой воде и продуктах питания. Источник данных-региональный информационный фонд социальногигиенического мониторинга, Территориальный орган Федеральной службы государственной статистики. Осуществлен анализ продуктов как регионального происхождения, так и привозных. Установлено, что население области потребляет на 93 кг продуктов питания (на одного человека) больше, чем в среднем по России. Рассчитанные концентрации веществ в продуктах питания и в питьевой воде соответствуют гигиеническим требованиям. Первое ранговое место по вкладу в общее значение экспозиции свинцом, кадмием и мышьяком занимают молочные продукты. Второе и третье места занимают овощи и бахчевые и хлебные продукты соответственно. Первое ранговое место по вкладу в общее значение экспозиции ртутью занимают овощи и бахчевые, второе-хлебные продукты, третье-молочные продукты. Оценка неканцерогенного риска показала, что коэффициенты опасности от содержания тяжелых металлов в продуктах питания и питьевой воде в пределах приемлемого риска. Общий канцерогенный риск (TCR) находится на неприемлемом уровне для населения (1,5Е-03). Число дополнительных случаев онкологических заболеваний в регионе при наихудшем сценарии может достигать 557 случаев (в течение 70 лет). Ключевые слова: продукты питания, питьевая вода, тяжелые металлы, оценка риска здоровью, неканцерогенный риск, онкологические заболевания, комбинированное действие, пероральное поступление.

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Potentially toxic elements in freshwater (Alburnus spp.) and marine (Sardina pilchardus) sardines from the Western Balkan Peninsula: An assessment of human health risk and management

Cited by 15 publications

References 30 publications

Reference Measurements for Priority and Essential Trace Elements and Methyl Mercury with Isotope Dilution Inductively Coupled Plasma-Mass Spectrometry for Seafood Safety Assessment and CRM Production

Reference Measurements for Priority and Essential Trace Elements and Methyl Mercury with Isotope Dilution Inductively Coupled Plasma-Mass Spectrometry for Seafood Safety Assessment and CRM Production

Hygienic assessment of population health risks caused by combined oral introduction of heavy metals

Hygienic assessment of population health risks caused by combined oral introduction of heavy metals

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