Potentially -malignant disorders

Abstract

It is estimated that more than one million new oral cancer cases are being detected annually in the Indian subcontinent, of which 90% are oral squamous cell carcinoma (OSCC). Oral potentially malignant disorder (OPMD) are associated with increased rate of occurrence of OSCC of lips or oral cavity. Transformation of oral cancer from OPMD is common, especially in South Asian countries like India, where tobacco and arecanut consumption is prevalent. Early diagnosis and timely treatment of PMD’s may help to prevent its malignant transformation into oral cancer. The aim of the article is to highlight the risk factors, etiology, clinical presentation of PMD, thus helps in early detection and treatment, thereby reducing incidence of oral cancer.

Novel tetrahydrocurcumin integrated mucoadhesive nanocomposite κ-carrageenan/xanthan gum sponges: a strategy for effective local treatment of oral cancerous and precancerous lesions

“…Most OSCC arise from precancerous lesions in the oral mucosal lining (Oyapero et al., 2020 ; Habibi et al., 2023 ). Oral precancerous lesions (OPL) are morphologically altered tissues in which oral cancer is more likely to occur; they often present as either white or red patches, known as leukoplakia and erythroplakia, respectively (Shaji et al., 2022 ). OPL has gained attention because of the increased risk of cancer development in the oral cavity.…”