Potential of pulsed light technology for control of SARS-CoV-2 in hospital environments

Jean, Julie; Rodríguez-López, María Isabel; Jubinville, Éric; Núñez‐Delicado, Estrella; Gómez‐López, Vicente M.

doi:10.1016/j.jphotobiol.2020.112106

Cited by 9 publications

(6 citation statements)

References 100 publications

(102 reference statements)

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“…As a result, we end up with a supplementary surface and high distribution of UVC radiation through the whole volume of the contaminated fluids. This method of decontamination may be improved using the short pulses of UVC radiation [ 54 , 55 ]. Therefore, focusing the radiation inside the decontamination core and using the quartz metamaterials help us to optimize both of the intensity(number) of UVC sources for certain pathogens and exposition time and finally get a feasible critical intensity for almost complete decontamination, particularly, if using low-intensity lamps.…”

Section: Discussionmentioning

confidence: 99%

UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment

et al. 2022

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A semiclassical (light classical and molecule quantum) model describing the dependence of DNA/RNA dimerization rate as function of the ultraviolet C (UVC) radiation’s intensity is proposed. Particularly, a nonlinear model is developed based on the Raman-like processes in quantum optics. The main result of the theory shows that the process of dimerization in the DNA/RNA depends strongly on the UVC light’s intensity, thus proving a possible quantum microscopical mechanism of the interaction of UV light with the DNA. To corroborate the theoretical findings, we realize some experiments, by which want to investigate how the inactivation rate of the yeast colonies depends on the intensity of the UVC irradiation. The experimental results evidence a nonlinear decreasing of the residual yeast colonies as a function of the intensity in the irradiation process. The possibilities to optimize the intensity of UVC radiation in the considered decontamination equipment by using metamaterials are studied. The application of such equipment in disinfection of fluids (air, water, droplets, etc.), as well for the SARS-CoV-2-infected aerosols, is discussed.

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Section: Discussionmentioning

confidence: 99%

UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment

et al. 2022

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“…The same low inactivation rate was observed for coliphage MS2 inoculated on chopped mint, pepper, and garlic (Belliot et al., 2013). Comprehensive data on the level of inactivation obtained for 22 different viruses treated with pulsed light recently has been published (Jean et al., 2021). The rather limited efficacy of pulsed light in real food matrices versus in vitro studies is typical for light‐based inactivation technologies.…”

Section: Physical Control Measures: Mode Of Action and Efficiencymentioning

confidence: 99%

New food safety challenges of viral contamination from a global perspective: Conventional, emerging, and novel methods of viral control

Ezzatpanah

Gómez‐López

Koutchma

et al. 2022

Comp Rev Food Sci Food Safe

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Food‐ and waterborne viruses, such as human norovirus, hepatitis A virus, hepatitis E virus, rotaviruses, astroviruses, adenoviruses, and enteroviruses, are major contributors to all foodborne illnesses. Their small size, structure, and ability to clump and attach to inanimate surfaces make viruses challenging to reduce or eliminate, especially in the presence of inorganic or organic soils. Besides traditional wet and dry methods of disinfection using chemicals and heat, emerging physical nonthermal decontamination techniques (irradiation, ultraviolet, pulsed light, high hydrostatic pressure, cold atmospheric plasma, and pulsed electric field), novel virucidal surfaces, and bioactive compounds are examined for their potential to inactivate viruses on the surfaces of foods or food contact surfaces (tools, equipment, hands, etc.). Every disinfection technique is discussed based on its efficiency against viruses, specific advantages and disadvantages, and limitations. Structure, genomic organization, and molecular biology of different virus strains are reviewed, as they are key in determining these techniques effectiveness in controlling all or specific foodborne viruses. Selecting suitable viral decontamination techniques requires that their antiviral mechanism of action and ability to reduce virus infectivity must be taken into consideration. Furthermore, details about critical treatments parameters essential to control foodborne viruses in a food production environment are discussed, as they are also determinative in defining best disinfection and hygiene practices preventing viral infection after consuming a food product.

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“…Recent works have particularly shown the efficacy of UV-C in completely inactivating corona viruses, including SARS-CoV-2, on surfaces or aerosols [ 7 , 8 , 9 , 10 ]. Research on portable light sources emitting UV-C wavelengths has seen tremendous growth, especially due to demands for sterilizing surfaces [ 11 , 12 ]. It is expected that development of portable UV-C detectors would follow suit.…”

Section: Introductionmentioning

confidence: 99%

Ultraviolet-C Photoresponsivity Using Fabricated TiO2 Thin Films and Transimpedance-Amplifier-Based Test Setup

Cadatal-Raduban

Pope

Olejníček

et al. 2022

Sensors

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We report on fabricated titanium dioxide (TiO2) thin films along with a transimpedance amplifier (TIA) test setup as a photoconductivity detector (sensor) in the ultraviolet-C (UV-C) wavelength region, particularly at 260 nm. TiO2 thin films deposited on high-resistivity undoped silicon-substrate at thicknesses of 100, 500, and 1000 nm exhibited photoresponsivities of 81.6, 55.6, and 19.6 mA/W, respectively, at 30 V bias voltage. Despite improvements in the crystallinity of the thicker films, the decrease in photocurrent, photoconductivity, photoconductance, and photoresponsivity in thicker films is attributed to an increased number of defects. Varying the thickness of the film can, however, be leveraged to control the wavelength response of the detector. Future development of a chip-based portable UV-C detector using TiO2 thin films will open new opportunities for a wide range of applications.

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Potential of pulsed light technology for control of SARS-CoV-2 in hospital environments

Cited by 9 publications

References 100 publications

UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment

UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment

New food safety challenges of viral contamination from a global perspective: Conventional, emerging, and novel methods of viral control

Ultraviolet-C Photoresponsivity Using Fabricated TiO2 Thin Films and Transimpedance-Amplifier-Based Test Setup

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