Abstract:Aim. Polypharmacy may increase the prevalence of potential multidrug
interactions (pMDIs), where one drug interacts with two or more other
drugs, possibly amplifying the risk of a potential adverse drug event
(pADE). The major goal of this study was to estimate the prevalence of
amplifying pMDIs in an ambulatory cohort of older patients. Methods.
Current medication lists of 22033 randomly chosen outpatients ≥50 years
old were extracted from the New York Presbyterian Hospital (NYP) data
warehouse. Network analy… Show more
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