Potential Health Risks of Zn, Fe, and Pb in Medical Skin Creams and Cosmetic Products Derived from Plants in Iraq

Lawi, Dhuha Jalil; Abdulwhaab, Waleed Salah; Abojassim, Ali Abid

doi:10.1007/s12011-022-03493-z

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…However, especially since the age of the industrial revolution starting in the mid-18th century, anthropogenic activities have created a major problem with regard to the aspects of environmental pollution and the poisoning of food chains [ 1 , 2 ]. In particular, the accumulation of heavy metals that enter the organism as part of people’s daily activities, e.g., through food, cosmetics or the abovementioned increasing pollution of the environment, represents an ever-increasing problem [ 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

The Role of Trace Elements in Cardiovascular Diseases

Wechselberger,

Messner,

Bernhard

2023

Toxics

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Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.

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Section: Introductionmentioning

confidence: 99%

The Role of Trace Elements in Cardiovascular Diseases

Wechselberger,

Messner,

Bernhard

2023

Toxics

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Assessment of Heavy Metals in Biscuit Samples Available in Iraqi Markets

Taher,

Abojassim

2023

Biol Trace Elem Res

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Multivariate Statistical Analysis of Cosmetics Due to Potentially Toxic/Heavy Metal(loid) Contamination: Source Identification for Sustainability and Human Health Risk Assessment

Ahmed,

Ahmad,

Sohail

et al. 2024

Sustainability

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Cosmetics are a staple in daily beauty routines worldwide, embraced for their role in enhancing personal appearance and self-care. However, their direct application exposes the skin to a range of ingredients, including metal(loid)s, and these can have a hazardous impact on human health if they exceed the limits defined by regulatory agencies. As a result, it is important to evaluate metal(loid) levels to ensure the safety of these cosmetic products. This research aimed to analyze several cosmetic products (massage cream, cleaner, mud mask, skin polish, scrub, lipstick, foundation, lotion, face powder, and highlighter) for metalloids (Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, As, Sb, Cd, Pb, Bi, and Hg) by using inductively coupled plasma-optical emission spectrometry (ICP-OES). Multivariate and bivariate statistical approaches were used to interpret the sources and association between the metal(loid)s. The concentration ranges of metals were found to be Al (1.18–4.15 mg/kg), Cr (0.13–2.19 mg/kg), Mn (1.89–28.77 mg/kg), Fe (4.09–126.02 mg/kg), Co (0.19–31.62 mg/kg), Ni (0.11–5.39 mg/kg), Cu (0.08–0.19 mg/kg), Zn (1.99–47.81 mg/kg), Sr (0.99–10.34 mg/kg), Cd (0.16–1.50 mg/kg), Pb (0.29–2.44 mg/kg), Bi (0.23–2.18 mg/kg), and Hg (0.012–0.42 mg/kg), whereas the concentration ranges of metalloids were found to be As (0.011–0.051 mg/kg) and Sb (0.042–1.66 mg/kg). Among the tested cosmetic products for the metal(loid) levels, the estimation of the margin of safety (MOS < 100), hazard quotient (HQ > 1), hazard index (HI > 1), and cumulative cancer risk (LCR ≤ 1 × 10−3) indicated non-carcinogenic and carcinogenic health risks associated with the use of few products. Most of the cosmetics products under investigation are safe with respect to non-carcinogenic and carcinogenic health risks. By highlighting the need to limit excessive use and adhering to sustainable safety practices, this study underscores the importance of monitoring and regulating metal(loid) content to ensure consumer safety and mitigate environmental impact.

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Potential Health Risks of Zn, Fe, and Pb in Medical Skin Creams and Cosmetic Products Derived from Plants in Iraq

Cited by 3 publications

References 16 publications

The Role of Trace Elements in Cardiovascular Diseases

The Role of Trace Elements in Cardiovascular Diseases

Assessment of Heavy Metals in Biscuit Samples Available in Iraqi Markets

Multivariate Statistical Analysis of Cosmetics Due to Potentially Toxic/Heavy Metal(loid) Contamination: Source Identification for Sustainability and Human Health Risk Assessment

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