2015
DOI: 10.1542/peds.2014-2015
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Potential Drug−Drug Interactions in Infant, Child, and Adolescent Patients in Children’s Hospitals

Abstract: BACKGROUND AND OBJECTIVES: Hospitalized infants, children, and adolescents are typically exposed to numerous distinct medications during inpatient admissions, increasing their risk of potential drug2drug interactions (PDDIs). We assessed the prevalence and characteristics of PDDI exposure of pediatric patients treated in children's hospitals.

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Cited by 101 publications
(130 citation statements)
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References 27 publications
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“…The present study was conducted with aim and objective to identify and evaluate the drug-drug interactions in paediatric outpatient department. In present study prevalence of DDIs were more in male as compare to females which was contrast to the study done by Feinstein J et al 10 showed equal occurrence of DDIs in male and female. It suggests that their prevalence could differ in individual gender.…”
Section: Discussioncontrasting
confidence: 99%
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“…The present study was conducted with aim and objective to identify and evaluate the drug-drug interactions in paediatric outpatient department. In present study prevalence of DDIs were more in male as compare to females which was contrast to the study done by Feinstein J et al 10 showed equal occurrence of DDIs in male and female. It suggests that their prevalence could differ in individual gender.…”
Section: Discussioncontrasting
confidence: 99%
“…In present study, the overall prevalence of DDIs was 16 % out of all DDIs. Prevalence rate was lower in compare to studies conducted by Feinstein et al 10 and Qorraj-Bytyqi et al, 12 they reported that paediatric patients exposed to DDI were 49% and 23% respectively. DDI severity criteria enhances decision making ability by assessing risk versus benefit alternatives.…”
Section: Decrease Sedative Effectmentioning
confidence: 54%
“…Pasien dengan jumlah kunjungan rawat inap terbanyak diketahui memiliki riwayat komorbiditas lompokkan berdasarkan klasifikasi berikut, 16 a. Tingkat keparahan…”
Section: Hasilunclassified
“…Disebutkan bahwa terdapat minimal satu pasang kombinasi obat yang berpotensi menyebabkan interaksi pada 887 resep (49,7%) menggunakan perangkat lunak pemindai interaksi obat Micromedex Drug Reax®. 16 Berdasarkan data 214 kunjungan rawat inap pada periode Januari -Desember 2014, diperoleh 107 pasang jenis obat yang dapat menyebabkan PIOO dengan total frekuensi kejadian sebanyak 1000 kasus. Angka kejadian PIOO yang tinggi dikhawatirkan dapat berakibat buruk terhadap pasien.…”
Section: Pembahasanunclassified
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