Potential Applications of Carbon Nanotubes

Endo, Morinobu; Strano, Michael S.; Ajayan, Pulickel M.

doi:10.1007/978-3-540-72865-8_2

Cited by 399 publications

(249 citation statements)

References 199 publications

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“…[1][2][3][4] This is mainly due to their unusual electrical, thermal and mechanical properties. [1,2] The use of carbon nanotubes might open a new era in the design of supercapacitors and batteries, nanoscale sensors, electromechanical actuators, separation membranes, drug delivery systems or filled polymer composites. [2,3] For this reason the quality control of CNT materials and the employed CNT dispersions play a key role for an industrial application.…”

Section: Introductionmentioning

confidence: 99%

“…[1,2] The use of carbon nanotubes might open a new era in the design of supercapacitors and batteries, nanoscale sensors, electromechanical actuators, separation membranes, drug delivery systems or filled polymer composites. [2,3] For this reason the quality control of CNT materials and the employed CNT dispersions play a key role for an industrial application. [4][5][6] This means that the establishment of a fast and easy quality control method is essential for a successful product.…”

Section: Introductionmentioning

confidence: 99%

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New strategies for the chemical characterization of multi-walled carbon nanotubes and their derivatives

et al. 2012

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

New strategies for the chemical characterization of multi-walled carbon nanotubes and their derivatives

et al. 2012

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“…Recently, MWCNTs have been commercially supplied as an additive for Li-Ion batteries, fuel cells and capacitors (formerly known as condensers) produced by Japanese companies. The bulk volumes of manufactured MWCNTs have already reached a few hundred tons per year [8]. Investigations of potential medical applications are also being considered [9].…”

Section: Introductionmentioning

confidence: 99%

Cellular cytotoxic response induced by highly purified multi-wall carbon nanotube in human lung cells

Tsukahara

Haniu

2011

Mol Cell Biochem

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Carbon nanotubes, a promising nanomaterial with unique characteristics, have applications in a variety of fields. The cytotoxic effects of carbon nanotubes are partially due to the induction of oxidative stress; however, the detailed mechanisms of nanotube cytotoxicity and their interaction with cells remain unclear. In the present study, we focus on the acute toxicity of vapor-grown carbon fiber, HTT2800, which is one of the most highly purified multi-wall carbon nanotube (MWCNT) by high-temperature thermal treatment. We exposed human bronchial epithelial cells (BEAS-2B) to HTT2800 and measured the cellular uptake, mitochondrial function, cellular LDH release, apoptotic signaling, reactive oxygen species (ROS) generation and pro-inflammatory cytokine release. The HTT2800-exposed cells showed cellular uptake of the carbon nanotube, increased cell death, enhanced DNA damage and induced cytokine release. However, the exposed cells showed no obvious intracellular ROS generation. These cellular and molecular findings suggest that HTT2800 could cause a potentially adverse inflammatory response in BEAS-2B cells.

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“…In recent years, a wide range of different nanoscale drug delivery vectors have been evaluated (Pan et al, 2004;Chithrani et al, 2006;Endo et al, 2008). Notably, single-walled carbon nanotubes (SWCNTs) have attracted considerable interest in this regard, as they offer potential advantages over the more widely studied metal nanoparticle systems.…”

Section: Carbon Nanotubes and Their Impor-tance In Anticancer Drug Dementioning

confidence: 99%

Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review

Kushwaha¹,

Ghoshal²,

Kumar³

et al. 2013

Braz. J. Pharm. Sci.

114

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Carbon nanotubes (CNTs) were discovered in 1991 and shown to have certain unique physicochemical properties, attracting considerable interest in their application in various fields including drug delivery. The unique properties of CNTs such as ease of cellular uptake, high drug loading, thermal ablation, among others, render them useful for cancer therapy. Cancer is one of the most challenging diseases of modern times because its therapy involves distinguishing normal healthy cells from affected cells. Here, CNTs play a major role because phenomena such as EPR, allow CNTs to distinguish normal cells from affected ones, the Holy Grail in cancer therapy. Considerable work has been done on CNTs as drug delivery systems over the last two decades. However, concerns over certain issues such as biocompatibility and toxicity have been raised and warrant extensive research in this field.Uniterms: Carbon nanotubes/properties. Carbon nanotubes/use/drugs delivery. Single-Walled Carbon Nanotube. Multiwalled Carbon Nanotube. Anticancer drugs/delivery. Cancer/therapy. Drugs/delivery.Os nanotubos de carbono foram descobertos em 1991 e suas propriedades físico-químicas únicas demonstradas, despertando interesse em sua aplicação em vários campos, incluindo a entrega liberação de fármacos. As propriedades únicas dos nanotubos de carbono, tais como a facilidade de captação pela célula, carga alta de fármaco, ablação térmica, entre outras, tornaram-nos úteis para terapia de câncer, uma das doenças mais difíceis dos tempos modernos, pois sua terapia envolve a distinção entre as células normais saudáveis e as afetadas pela doença. Os nanotubos de carbono têm um papel importante nessa área porque fenômenos como EPR permitem que estes possam distinguir as células normais das afetadas, que é o Santo Graal na terapia do câncer. Trabalho considerável tem sido feito ao longo das duas últimas década com nanotubos de carbono, como sistemas de liberação de fármacos. No entanto, preocupações sobre algumas questões, como biocompatibilidade e toxicidade, surgiram ao longo do tempo, demandando extensas pesquisa nesse campo. Unitermos: Nanotubos de carbono/propriedades. Nanotubos de carbono/uso/liberação de fármacos. Nanotubo de carbono de parede única. Nanotubo de parede múltipla. Fármacos anticancer/liberação. Cancer/tratamento. Fármacos/liberação.

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Potential Applications of Carbon Nanotubes

Cited by 399 publications

References 199 publications

New strategies for the chemical characterization of multi-walled carbon nanotubes and their derivatives

New strategies for the chemical characterization of multi-walled carbon nanotubes and their derivatives

Cellular cytotoxic response induced by highly purified multi-wall carbon nanotube in human lung cells

Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review

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