Postural Changes May Influence Popliteal Atherosclerosis by Modifying Local Circumferential Wall Tension

Gemignani, Tiago; Matos‐Souza, José R.; Coelho, Otávio Rizzi; Franchini, Kleber G.; Nadruz, Wilson

doi:10.1291/hypres.31.2059

Cited by 14 publications

(33 citation statements)

References 29 publications

(39 reference statements)

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“…Indeed, systolic BP following exposure to UV-A also tended to be lower than in the control trial suggesting that this small absolute increase in plasma nitrite was substantial enough to induce physiological effects. While we can only speculate as to mechanisms underpinning the reduction in nitrite during SHAM trials, it is well established that circumferential wall tension and arterial strain are reduced in the supine position compared to standing (Gemignani et al, 2008). A reduction in arterial shear stress is also associated with reduced NO production by the endothelial cells (Davies, 1995).…”

Section: Effects Of Uv-a Light On Plasma Nitrite and Blood Pressurementioning

confidence: 93%

Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

et al. 2015

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Dietary nitrate supplementation has been shown to increase nitric oxide (NO) metabolites, reduce blood pressure (BP) and enhance exercise performance. Acute exposure to ultraviolet (UV)-A light also increases NO bioavailability and reduces BP. We conducted a randomized, counterbalanced placebo-controlled trial to determine the effects of UV-A light alone and in combination with nitrate on the responses to sub-maximal steady-state exercise and time trial (TT) performance. Nine cyclists (VO2max 53.1 ± 4.4 ml/kg/min) completed five performance trials comprising 10 min submaximal steady-state cycling followed by a 16.1 km TT. s; d=0.28) compared to PLA + SHAM. These findings demonstrate that exposure to UV-A light alone does not alter the physiological responses to exercise or improve performance a laboratory setting. A combination of UV-A and NIT, however, does improve cycling TT performance in this environment which may be due to a larger increase in NO availability.

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Section: Effects Of Uv-a Light On Plasma Nitrite and Blood Pressurementioning

confidence: 93%

Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

et al. 2015

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“…Common carotid artery IMT and diameters as well ICRI were obtained as the average from both right and left arteries measurements. Carotid ultrasound and concomitant brachial blood pressure measurements were used to calculate Young’s Elastic Modulus, Artery Compliance and Stiffness Index [19] and peak and mean circumferential wall tension [20]. …”

Section: Methodsmentioning

confidence: 99%

Relationship between serum uric acid and internal carotid resistive index in hypertensive women: a cross-sectional study

Cipolli

Ferreira-Sae

Martins

et al. 2012

BMC Cardiovasc Disord

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BackgroundThe impact of serum uric acid (SUA) on arteries of hypertensive subjects remains to be fully established. This study investigated the relationship between SUA and carotid structural and hemodynamic parameters in hypertensive men and women.MethodsThree hundred and thirty eight patients (207 women and 131 men) were cross-sectionally evaluated by clinical, laboratory, hemodynamic and carotid ultrasound analysis. Common carotid diameters, circumferential wall tensions, Young’s Elastic Modulus, Stiffness Index, Arterial Compliance and intima-media thickness (IMT) were determined. Internal carotid artery resistive index (ICRI), a hemodynamic measure that reflects local vascular impedance and microangiopathy, was also assessed.ResultsUnivariate analysis showed no significant correlation of SUA with carotid diameters, elasticity/stiffness indexes, IMT and circumferential wall tensions in both genders. Conversely, SUA correlated with ICRI (r = 0.34; p < 0.001) in women, but not in men, and hyperuricemic women presented higher ICRI than normouricemic ones (0.684 ± 0.007 vs. 0.649 ± 0.004; p < 0.001). Stepwise and logistic regression analyses adjusted for potential confounding factors showed that ICRI was independently associated with SUA and hyperuricemia in women.ConclusionsThis study demonstrated that SUA was associated with ICRI in hypertensive women, suggesting that there might gender-related differences in the relationship between SUA and vascular damage in subjects with systemic hypertension.

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“…BP was measured by the same investigator in the upper and lower limbs using validated digital oscillometric devices (HEM-705CP; Omron Healthcare, Kyoto, Japan), with appropriate cuff sizes as previously described. 9 Two readings were averaged, and if they differed by >5 mm Hg, one additional measurement was performed and then averaged. BP was simultaneously measured with one device on the right arm and another device on the right calf with the subject lying in a supine position for 10 min.…”

Section: Original Contributionsmentioning

confidence: 99%

Leg Blood Pressure Measured in Orthostatic Posture Is Associated With Left Ventricular Mass in Normotensive Subjects

et al. 2012

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Postural Changes May Influence Popliteal Atherosclerosis by Modifying Local Circumferential Wall Tension

Cited by 14 publications

References 29 publications

Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

Relationship between serum uric acid and internal carotid resistive index in hypertensive women: a cross-sectional study

Leg Blood Pressure Measured in Orthostatic Posture Is Associated With Left Ventricular Mass in Normotensive Subjects

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